Biochemistry, Molecular Biology, and Biophysics (TMED)

Research output

Research output per year 1966 1996 2000 2001 2002 2003 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024

• 2611 Article
• 142 Review article
• 67 Chapter
• 50 Comment/debate
• 90 More
  • 28 Letter
  • 23 Editorial
  • 13 Short survey
  • 9 Conference contribution
  • 6 Conference article
  • 4 Other contribution
  • 3 Paper
  • 2 Book
  • 2 Foreword/postscript

Research output per year

Research output per year

Search results

• 2024

  Age-associated accumulation of B cells promotes macrophage inflammation and inhibits lipolysis in adipose tissue during sepsis

  Carey, A., Nguyen, K., Kandikonda, P., Kruglov, V., Bradley, C., Dahlquist, K. J. V., Cholensky, S., Swanson, W., Badovinac, V. P., Griffith, T. S. & Camell, C. D., Mar 26 2024, In: Cell reports. 43, 3, 113967.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• AI-designed RF pulses enable fast pulsing heteronuclear multiple quantum coherence NMR experiment at high and ultra-high magnetic fields

  Subrahmanian, M. V. & Veglia, G., Feb 2 2024, In: Chemical Communications. 60, 16, p. 2240-2243 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Compound Metabolite 100%
  • Heteronuclear Multiple Quantum Coherence 97%
  • Nuclear magnetic resonance spectroscopy 95%
  • Organic compounds 88%
  • Biopolymers 87%

• A trapped covalent intermediate as a key catalytic element in the hydrolysis of a GH3 β-glucosidase: An X-ray crystallographic and biochemical study

  Hu, C., Wang, Y., Wang, W., Cui, W., Jia, X., Mayo, K. H., Zhou, Y., Su, J. & Yuan, Y., Apr 2024, In: International Journal of Biological Macromolecules. 265, 131131.

  Research output: Contribution to journal › Article › peer-review

• Chemi-Northern: a versatile chemiluminescent northern blot method for analysis and quantitation of RNA molecules

  Mckenney, K. M., Connacher, R. P., Dunshee, E. B. & Goldstrohm, A. C., Apr 2024, In: RNA. 30, 4, p. 448-462 15 p.

  Research output: Contribution to journal › Article › peer-review

• Contrasting views on the role of AMPK in autophagy

  Kim, D. H., Mar 2024, In: BioEssays. 46, 3, 2300211.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Deletion of exons 2 and 3 from Actb and cell immortalization lead to widespread, β-actin independent alterations in gene expression associated with cell cycle control

  Sundby, L. J., Southern, W. M., Sun, J., Patrinostro, X., Zhang, W., Yong, J. & Ervasti, J. M., Jun 2024, In: European Journal of Cell Biology. 103, 2, 151397.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cell Cycle Checkpoints 100%
  • Actins 86%
  • Exons 85%
  • Gene Expression 61%
  • Proteins 37%

• ent-Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2^-/- Mice^S

  Gochman, A., Do, T. Q., Kim, K., Schwarz, J. A., Thorpe, M. P., Blackwell, D. J., Ritschel, P. A., Smith, A. N., Rebbeck, R. T., Akers, W. S., Cornea, R. L., Laver, D. R., Johnston, J. N. & Knollmann, B. C., Mar 1 2024, In: Molecular Pharmacology. 105, 3, p. 194-201 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • verticilide 100%
  • Ryanodine Receptor Calcium Release Channel 47%
  • Sudden Cardiac Death 10%
  • Biological Products 9%
  • Cardiac Myocytes 9%

• Epigenome-wide association study of total nicotine equivalents in multiethnic current smokers from three prospective cohorts

  Huang, B. Z., Binder, A. M., Quon, B., Patel, Y. M., Lum-Jones, A., Tiirikainen, M., Murphy, S. E., Loo, L., Maunakea, A. K., Haiman, C. A., Wilkens, L. R., Koh, W. P., Cai, Q., Aldrich, M. C., Siegmund, K. D., Hecht, S. S., Yuan, J. M., Blot, W. J., Stram, D. O., Le Marchand, L., & 1 othersPark, S. L., Mar 7 2024, In: American Journal of Human Genetics. 111, 3, p. 456-472 17 p.

  Research output: Contribution to journal › Article › peer-review

• Galactan induces macrophage M0 to M1 conversion to combat colon cancer

  Meng, Y., Yang, G., Ren, A., Qu, Y., Wang, X., Mayo, K. H., Zhou, Y. & Song, C., 2024, In: Food Science and Technology Research. 30, 1, p. 75-82 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Galactans 100%
  • Macrophage 76%
  • Macrophages 71%
  • Galactan 63%
  • galactans 57%

• Inflammaging and fatty acid oxidation in monocytes and macrophages

  Kruglov, V., Jang, I. H. & Camell, C. D., Jan 19 2024, In: Immunometabolism (United States). 6, 1, p. E00038

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Fatty Acids 100%
  • Monocytes 97%
  • Macrophages 82%
  • Pyrin Domain 21%
  • Receptor for Advanced Glycation End Products 19%

• Isomerization of proline-46 in the N-terminal tail of galectin-3 enhances T cell apoptosis via the ROS-ERK pathway

  Zhao, Z., Wang, M., Miller, M. C., He, Z., Xu, X., Zhou, Y., Mayo, K. H. & Tai, G., Jan 2024, In: International Journal of Biological Macromolecules. 256, 128304.

  Research output: Contribution to journal › Article › peer-review

  • Galectin 3 100%
  • MAP Kinase Signaling System 83%
  • Proline 80%
  • Isomerization 59%
  • T-Lymphocytes 46%

• Measuring Poly-Adenosine Tail Length of RNAs by High-Resolution Northern Blotting Coupled with RNase H Cleavage

  Arvola, R. M. & Goldstrohm, A. C., 2024, Methods in Molecular Biology. Humana Press Inc., p. 93-111 19 p. (Methods in Molecular Biology; vol. 2723).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Ribonuclease H 100%
  • Northern Blotting 68%
  • Adenosine 68%
  • RNA 48%
  • Messenger RNA 39%

• Mesoscale DNA features impact APOBEC3A and APOBEC3B deaminase activity and shape tumor mutational landscapes

  Sanchez, A., Ortega, P., Sakhtemani, R., Manjunath, L., Oh, S., Bournique, E., Becker, A., Kim, K., Durfee, C., Temiz, N. A., Chen, X. S., Harris, R., Lawrence, M. S. & Buisson, R., Dec 2024, In: Nature communications. 15, 1, 2370.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

  MISEV Consortium, Feb 2024, In: Journal of Extracellular Vesicles. 13, 2, e12404.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  20 Scopus citations

• Preface

  Valkov, E. & Goldstrohm, A. C., 2024, In: Methods in Molecular Biology. 2723, p. v

  Research output: Contribution to journal › Editorial › peer-review

• Preparation and identification of galacto-mannooligosaccharides generated from guar gum by a recombinant β-mannanase from Bacteroides fragilis (BF0736)

  Wang, X., Yan, X., Liu, Y., Song, Z., Mayo, K. H., Sun, L., Cui, L. & Zhou, Y., Jul 2024, In: Food Hydrocolloids. 152, 109893.

  Research output: Contribution to journal › Article › peer-review

  • guar gum 100%
  • Bacteroides fragilis 87%
  • beta-mannosidase 85%
  • Galactose 67%
  • Glycoside Hydrolases 65%

• Preparation of β-galacto-oligosaccharides using a novel endo-1,4-β-galactanase from Penicillium oxalicum

  Yan, X., Wang, Y., Zhang, Y., Wang, X., Liu, Y., Cui, J., Mayo, K. H., Zhou, Y. & Cui, L., Jan 2024, In: International Journal of Biological Macromolecules. 254, 127966.

  Research output: Contribution to journal › Article › peer-review

  • Galactans 100%
  • Galactan 84%
  • Penicillium 77%
  • Oligosaccharides 63%
  • Solanum tuberosum 37%

• Retention of stress susceptibility in the mdx mouse model of Duchenne muscular dystrophy after PGC-1α overexpression or ablation of IDO1 or CD38

  Johnson, E. E., Michael Southern, W., Doud, B., Steiger, B., Razzoli, M., Bartolomucci, A. & Ervasti, J. M., Apr 1 2024, In: Human molecular genetics. 33, 7, p. 594-611 18 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Senotherapeutic drug treatment ameliorates chemotherapy-induced cachexia

  Englund, D. A., Jolliffe, A. M., Hanson, G. J., Aversa, Z., Zhang, X., Jiang, X., White, T. A., Zhang, L., Monroe, D. G., Robbins, P. D., Niedernhofer, L. J., Kamenecka, T. M., Khosla, S. & LeBrasseur, N. K., Jan 2024, In: JCI Insight. 9, 2, e169512.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cachexia 100%
  • Cellular Senescence 89%
  • Skeletal Muscle 64%
  • Drug Therapy 48%
  • Pharmaceutical Preparations 33%
  1 Scopus citations

• The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance

  Caswell, D. R., Gui, P., Mayekar, M. K., Law, E. K., Pich, O., Bailey, C., Boumelha, J., Kerr, D. L., Blakely, C. M., Manabe, T., Martinez-Ruiz, C., Bakker, B., De Dios Palomino Villcas, J., I. Vokes, N., Dietzen, M., Angelova, M., Gini, B., Tamaki, W., Allegakoen, P., Wu, W., & 65 othersHumpton, T. J., Hill, W., Tomaschko, M., Lu, W. T., Haderk, F., Al Bakir, M., Nagano, A., Gimeno-Valiente, F., de Carné Trécesson, S., Vendramin, R., Barbè, V., Mugabo, M., Weeden, C. E., Rowan, A., McCoach, C. E., Almeida, B., Green, M., Gomez, C., Nanjo, S., Barbosa, D., Moore, C., Przewrocka, J., Black, J. R. M., Grönroos, E., Suarez-Bonnet, A., Priestnall, S. L., Zverev, C., Lighterness, S., Cormack, J., Olivas, V., Cech, L., Andrews, T., Rule, B., Jiao, Y., Zhang, X., Ashford, P., Durfee, C., Venkatesan, S., Temiz, N. A., Tan, L., Larson, L. K., Argyris, P. P., Brown, W. L., Yu, E. A., Rotow, J. K., Guha, U., Roper, N., Yu, J., Vogel, R. I., Thomas, N. J., Marra, A., Selenica, P., Yu, H., Bakhoum, S. F., Chew, S. K., Reis-Filho, J. S., Jamal-Hanjani, M., Vousden, K. H., McGranahan, N., Van Allen, E. M., Kanu, N., Harris, R. S., Downward, J., Bivona, T. G. & Swanton, C., Jan 2024, In: Nature Genetics. 56, 1, p. 60-73 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ErbB Receptors 100%
  • Non-Small Cell Lung Carcinoma 93%
  • Lung 67%
  • Apolipoproteins B 46%
  • Neoplasms 40%
  4 Scopus citations

• Thrombospondin proteins – Versatile extracellular proteins with multiple biological functions

  Adolph, K. W., Mar 1 2024, In: Seminars in Cell and Developmental Biology. 155, p. 1-2 2 p.

  Research output: Contribution to journal › Editorial › peer-review

• ULK1 seen at the single-molecule level during autophagy initiation

  Banerjee, C., Puchner, E. M. & Kim, D. H., 2024, In: Autophagy. 20, 3, p. 707-708 2 p.

  Research output: Contribution to journal › Article › peer-review
• 2023

  2019 Association of Biomolecular Resource Facilities Multi-Laboratory Data-Independent Acquisition Proteomics Study

  Kirkpatrick, J., Stemmer, P. M., Searle, B. C., Herring, L. E., Martin, L. R., Midha, M. K., Phinney, B. S., Shan, B., Palmblad, M., Wang, Y., Jagtap, P. D. & Neely, B. A., Jul 1 2023, In: Journal of Biomolecular Techniques. 34, 2, 3fc1f5fe.9b78d780.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteomics 100%
  • Datasets 86%
  • Benchmarking 58%
  • Libraries 48%
  • Ions 44%

• ACOT1 deficiency attenuates high-fat diet–induced fat mass gain by increasing energy expenditure

  Heden, T. D., Franklin, M. P., Dailey, C., Mashek, M. T., Chen, C. & Mashek, D. G., 2023, In: JCI Insight. 8, 18, e160987.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Acyl Coenzyme A 100%
  • Energy Metabolism 67%
  • Fats 56%
  • Uncoupling Protein 2 55%
  • Obesity 34%
  2 Scopus citations

• Acute expression of human APOBEC3B in mice results in RNA editing and lethality

  Alonso de la Vega, A., Temiz, N. A., Tasakis, R., Somogyi, K., Salgueiro, L., Zimmer, E., Ramos, M., Diaz-Jimenez, A., Chocarro, S., Fernández-Vaquero, M., Stefanovska, B., Reuveni, E., Ben-David, U., Stenzinger, A., Poth, T., Heikenwälder, M., Papavasiliou, N., Harris, R. S. & Sotillo, R., Dec 2023, In: Genome biology. 24, 1, 267.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • RNA Editing 100%
  • RNA editing 97%
  • RNA 74%
  • mice 41%
  • cytosine deaminase 24%
  2 Scopus citations

• Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein

  Braun, A. R., Kochen, N. N., Yuen, S. L., Liao, E. E., Cornea, R. L., Thomas, D. D. & Sachs, J. N., Jan 1 2023, In: ASN Neuro. 15

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Energy Transfer 100%
  • Biosensing Techniques 92%
  • alpha-Synuclein 91%
  • Fluorescence 62%
  • Proanthocyanidins 30%
  1 Scopus citations

• A Galaxy of informatics resources for MS-based proteomics

  Mehta, S., Bernt, M., Chambers, M., Fahrner, M., Föll, M. C., Gruening, B., Horro, C., Johnson, J. E., Loux, V., Rajczewski, A. T., Schilling, O., Vandenbrouck, Y., Gustafsson, O. J. R., Thang, W. C. M., Hyde, C., Price, G., Jagtap, P. D. & Griffin, T. J., 2023, In: Expert Review of Proteomics. 20, 11, p. 251-266 16 p.

  Research output: Contribution to journal › Review article › peer-review

  • Galaxies 100%
  • Informatics 76%
  • Ecosystem 71%
  • Proteomics 55%
  • Mass Spectrometry 54%
  1 Scopus citations

• Aging and chronic inflammation: highlights from a multidisciplinary workshop

  Saavedra, D., Añé-Kourí, A. L., Barzilai, N., Caruso, C., Cho, K. H., Fontana, L., Franceschi, C., Frasca, D., Ledón, N., Niedernhofer, L. J., Pereira, K., Robbins, P. D., Silva, A., Suarez, G. M., Berghe, W. V., von Zglinicki, T., Pawelec, G. & Lage, A., Dec 2023, In: Immunity and Ageing. 20, 1, 25.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Cellular Senescence 100%
  • Education 57%
  • Inflammation 53%
  • Psychological Phenomena 40%
  • Cytomegalovirus 30%
  13 Scopus citations

• Analyzing somatic mutations by single-cell whole-genome sequencing

  Zhang, L., Lee, M., Maslov, A. Y., Montagna, C., Vijg, J. & Dong, X., 2023, (Accepted/In press) In: Nature Protocols.

  Research output: Contribution to journal › Article › peer-review

  • Whole Genome Sequencing 100%
  • Mutation 72%
  • Displacement 29%
  • Cell Separation 25%
  • Cell Nucleus 22%
  1 Scopus citations

• An efficient protocol for preparing linear β-manno-oligosaccharides

  Cui, L., Wang, X., Wang, C., Yan, Y., Zhang, M., Mayo, K. H., Sun, L. & Zhou, Y., Oct 2023, In: Carbohydrate Research. 532, 108895.

  Research output: Contribution to journal › Article › peer-review

  • Oligosaccharides 100%
  • Polysaccharide Structure 70%
  • High-Performance Anion-Exchange Chromatography With Pulsed Amperometric Detection 69%
  • Polymerization Reaction 53%
  • Matrix Assisted Laser Desorption Ionization - Time of Flight (MALDI-TOF) 51%
  2 Scopus citations

• An NMR portrait of functional and dysfunctional allosteric cooperativity in cAMP-dependent protein kinase A

  Olivieri, C., Walker, C., Veliparambil Subrahmanian, M., Porcelli, F., Taylor, S. S., Bernlohr, D. A. & Veglia, G., Apr 2023, In: FEBS Letters. 597, 8, p. 1055-1072 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Cyclic AMP-Dependent Protein Kinases 100%
  • Magnetic Resonance Spectroscopy 80%
  • Protein Kinase C 75%
  • NMR Spectroscopy 64%
  • Phosphotransferases 62%
  4 Scopus citations

• An optimized workflow for MS-based quantitative proteomics of challenging clinical bronchoalveolar lavage fluid (BALF) samples

  Weise, D. O., Kruk, M. E., Higgins, L. A., Markowski, T. W., Jagtap, P. D., Mehta, S., Mickelson, A., Parker, L. L., Wendt, C. H. & Griffin, T. J., Dec 2023, In: Clinical Proteomics. 20, 1, 14.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Workflow 100%
  • Bronchoalveolar Lavage Fluid 97%
  • Proteomics 83%
  • Mass Spectrometry 81%
  • Protein 37%

• An Oral Galectin Inhibitor in COVID-19—A Phase II Randomized Controlled Trial

  Sigamani, A., Mayo, K. H., Miller, M. C., Chen-Walden, H., Reddy, S. & Platt, D., Apr 2023, In: Vaccines. 11, 4, 731.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Galectins 100%
  • SARS Virus 85%
  • Clearance 78%
  • Galectin 3 76%
  • Antagonist 67%
  4 Scopus citations

• A paradigm shift: AMPK negatively regulates ULK1 activity

  Park, J. M. & Kim, D. H., 2023, (Accepted/In press) In: Autophagy.

  Research output: Contribution to journal › Article › peer-review

  • Adenosine Monophosphate 100%
  • Protein Kinases 82%
  • Phosphotransferases 69%
  • Autophagy 47%
  • Class III Phosphatidylinositol 3-Kinases 35%
  2 Scopus citations

• APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer

  McCann, J. L., Cristini, A., Law, E. K., Lee, S. Y., Tellier, M., Carpenter, M. A., Beghè, C., Kim, J. J., Sanchez, A., Jarvis, M. C., Stefanovska, B., Temiz, N. A., Bergstrom, E. N., Salamango, D. J., Brown, M. R., Murphy, S., Alexandrov, L. B., Miller, K. M., Gromak, N. & Harris, R. S., Oct 2023, In: Nature Genetics. 55, 10, p. 1721-1734 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • R-Loop Structures 100%
  • Mutagenesis 61%
  • Single-Stranded DNA 25%
  • Neoplasms 20%
  • Deamination 13%
  4 Scopus citations

• APOBEC3 degradation is the primary function of HIV-1 Vif determining virion infectivity in the myeloid cell line THP-1

  Ikeda, T., Shimizu, R., Nasser, H., Carpenter, M. A., Cheng, A. Z., Brown, W. L., Sauter, D. & Harris, R., Aug 31 2023, In: mBio. 14, 4, p. e0078223

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myeloid Cells 100%
  • Virion 93%
  • HIV-1 85%
  • Cell Line 57%
  • THP-1 Cells 55%
  2 Scopus citations

• A report on the International Society for Cell & Gene Therapy 2022 Scientific Signature Series, “Therapeutic advances with native and engineered human extracellular vesicles”

  Toh, W. S., Yarani, R., El Andaloussi, S., Cho, B. S., Choi, C., Corteling, R., De Fougerolles, A., Gimona, M., Herz, J., Khoury, M., Robbins, P. D., Williams, D., Weiss, D. J., Rohde, E., Giebel, B. & Lim, S. K., Aug 2023, In: Cytotherapy. 25, 8, p. 810-814 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Extracellular Vesicles 100%
  • Cell- and Tissue-Based Therapy 80%
  • Genetic Therapy 78%
  • Therapeutics 13%
  • Animal Disease Models 11%
  5 Scopus citations

• Association of Urinary Biomarkers of Smoking-Related Toxicants with Lung Cancer Incidence in Smokers: The Multiethnic Cohort Study

  Cigan, S. S., Murphy, S. E., Stram, D. O., Hecht, S. S., Le Marchand, L., Stepanov, I. & Park, S. L., Mar 1 2023, In: Cancer Epidemiology Biomarkers and Prevention. 32, 3, p. 306-314 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Smokers 100%
  • Lung Neoplasms 93%
  • Smoking 85%
  • Cohort Studies 80%
  • hydroxycotinine 78%
  2 Scopus citations

• Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used

  Harrison, D. E., Strong, R., Reifsnyder, P., Rosenthal, N., Korstanje, R., Fernandez, E., Flurkey, K., Ginsburg, B. C., Murrell, M. D., Javors, M. A., Lopez-Cruzan, M., Nelson, J. F., Willcox, B. J., Allsopp, R., Watumull, D. M., Watumull, D. G., Cortopassi, G., Kirkland, J. L., Tchkonia, T., Choi, Y. G., & 9 othersYousefzadeh, M. J., Robbins, P. D., Mitchell, J. R., Acar, M., Sarnoski, E. A., Bene, M. R., Salmon, A., Kumar, N. & Miller, R. A., 2023, (Accepted/In press) In: GeroScience.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • dimethyl fumarate 100%
  • Meclizine 92%
  • fisetin 83%
  • 4-phenylbutyric acid 80%
  • Dimethyl Fumarate 80%
  1 Scopus citations

• Avidity-Based Method for the Efficient Generation of Monoubiquitinated Recombinant Proteins

  Nelson, S. L., Li, Y., Chen, Y. & Deshmukh, L., Apr 12 2023, In: Journal of the American Chemical Society. 145, 14, p. 7748-7752 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Recombinant proteins 100%
  • Recombinant Proteins 57%
  • Proteins 52%
  • Amyloidogenic Proteins 29%
  • Protein 23%
  5 Scopus citations

• Cardiac calcium regulation in human induced pluripotent stem cell cardiomyocytes: Implications for disease modeling and maturation

  Ernst, P., Bidwell, P. A., Dora, M., Thomas, D. D. & Kamdar, F., Jan 18 2023, In: Frontiers in Cell and Developmental Biology. 10, 986107.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Induced Pluripotent Stem Cells 100%
  • Cardiac Myocytes 82%
  • Calcium 60%
  • Technology 16%
  • Drug-Related Side Effects and Adverse Reactions 11%
  1 Scopus citations

• Cardiomyopathy-associated variants alter the structure and function of the α-actinin-2 actin-binding domain

  Atang, A. E., Rebbeck, R. T., Thomas, D. D. & Avery, A. W., Aug 30 2023, In: Biochemical and Biophysical Research Communications. 670, p. 12-18 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Actinin 100%
  • Cardiomyopathies 71%
  • Actins 62%
  • Mutation 62%
  • Thickening 45%

• CD11c regulates neutrophil maturation

  Hou, L., Voit, R. A., Shibamura-Fujiogi, M., Koutsogiannaki, S., Li, Y., Chen, Y., Luo, H., Sankaran, V. G. & Yuki, K., Apr 11 2023, In: Blood Advances. 7, 7, p. 1312-1325 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neutrophils 100%
  • Sepsis 39%
  • Bone Marrow 14%
  • Apoptosis 11%
  • Dendritic Cells 8%
  5 Scopus citations

• Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities

  Silwal, P., Nguyen-Thai, A. M., Mohammad, H. A., Wang, Y., Robbins, P. D., Lee, J. Y. & Vo, N. V., Apr 2023, In: Biomolecules. 13, 4, 686.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Intervertebral Disc Degeneration 100%
  • Cellular Senescence 87%
  • Disorder 68%
  • Catabolic 52%
  • Mechanical Stress 50%
  16 Scopus citations

• Compartment-specific protein interactions in beryllium lung disease

  Li, L., Vestal, B., Mroz, M. M., Liu, S., Macphail, K., Griffin, T. J., Yang, I. V., Maier, L. A. & Bhargava, M., 2023, In: ERJ Open Research. 9, 6, 00138-2023.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  1 Scopus citations

• Corrigendum to: A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A (The EMBO Journal, (2022), 41, 21, 10.15252/embj.2021110393)

  Simon, M., Yang, J., Gigas, J., Earley, E. J., Hillpot, E., Zhang, L., Zagorulya, M., Tombline, G., Gilbert, M., Yuen, S. L., Pope, A., Van Meter, M., Emmrich, S., Firsanov, D., Athreya, A., Biashad, S. A., Han, J., Ryu, S., Tare, A., Zhu, Y., & 11 othersHudgins, A., Atzmon, G., Barzilai, N., Wolfe, A., Moody, K., Garcia, B. A., Robbins, P. D., Vijg, J., Seluanov, A., Suh, Y. & Gorbunova, V., Feb 1 2023, In: EMBO Journal. 42, 3, e113326.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Lamin Type A 100%
  • Aged, 80 and over 87%
  • Deacetylation 84%
  • Genomic Instability 78%
  • Error 53%
  1 Scopus citations

• COVID-19 and cellular senescence

  Schmitt, C. A., Tchkonia, T., Niedernhofer, L. J., Robbins, P. D., Kirkland, J. L. & Lee, S., Apr 2023, In: Nature Reviews Immunology. 23, 4, p. 251-263 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Coronavirus 100%
  • Cellular Senescence 87%
  • SARS Virus 66%
  • Clinical Deterioration 14%
  • Extracellular Matrix 9%
  46 Scopus citations

• Desmoglein 2 Functions as a Receptor for Fatty Acid Binding Protein 4 in Breast Cancer Epithelial Cells

  Chen, D., Wirth, K. M., Kizy, S., Muretta, J. M., Markowski, T. W., Yong, P., Sheka, A., Abdelwahab, H., Hertzel, A. V., Ikramuddin, S., Yamamoto, M. & Bernlohr, D. A., Aug 1 2023, In: Molecular Cancer Research. 21, 8, p. 836-848 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Desmoglein 2 100%
  • Fatty Acid-Binding Proteins 73%
  • Mitogen-Activated Protein Kinase 3 44%
  • Mitogen-Activated Protein Kinase 1 42%
  • Epithelial Cells 40%
  1 Scopus citations

• Developing A Baseline Metabolomic Signature Associated with COVID-19 Severity: Insights from Prospective Trials Encompassing 13 U.S. Centers

  Yang, K., Kang, Z., Guan, W., Lotfi-Emran, S., Mayer, Z. J., Guerrero, C. R., Steffen, B. T., Puskarich, M. A., Tignanelli, C. J., Lusczek, E. & Safo, S. E., Nov 2023, In: Metabolites. 13, 11, 1107.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Metabolomics 100%
  • MAP Kinase Kinase 5 92%
  • Dihydroceramide 80%
  • Metabolic 73%
  • Metabolite 63%

• Discovery of Modified Metabolites, Secondary Metabolites, and Xenobiotics by Structure-Oriented LC-MS/MS

  Murray, K. J., Villalta, P. W., Griffin, T. J. & Balbo, S., Nov 20 2023, In: Chemical research in toxicology. 36, 11, p. 1666-1682 17 p.

  Research output: Contribution to journal › Review article › peer-review

  • Xenobiotic Agent 100%
  • Workflow 95%
  • Xenobiotics 94%
  • Liquid Chromatography 90%
  • Mass Spectrometry 77%