Projects per year
Organization profile
Organization profile
Chronic illnesses, such as diabetes, cancer, cardiovascular disease, and asthma, afflict large numbers of people in the United States and other countries. These diseases are complex, and often include components of inflammation or pain.
Faculty in the Chronic Disease Bioscience research cluster are investigating the biological underpinnings of persistent or recurring diseases in animal cell lines and disease models. Their research uncovers roles for the genes, molecules, and cells involved in the initiation and progression of chronic disease states.
This information is then used to develop innovative therapeutic strategies to alleviate diseases of frequent recurrence or long duration in animals and people.
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Profiles
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David R Brown
Person: Faculty
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John P Collister
- Veterinary and Biomedical Sciences - Associate Professor
- Chronic Disease Biology
Person: Faculty
Projects and Grants
- 38 Finished
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Veterinary Summer Scholars in Comparative Medicine
NATIONAL INSTITUTES OF HEALTH (NIH)
4/15/17 → 3/31/24
Project: Research project
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Relative Contribution of Trypsin and Inflammation in Acu
UNIVERSITY OF MIAMI, NATIONAL INSTITUTES OF HEALTH (NIH)
4/1/17 → 3/31/22
Project: Research project
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Improving vascular function and bacterial clearance duri
Walcheck, B., Arndt, P. G., Rao, S. & Seelig, D.
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
4/1/16 → 3/31/21
Project: Research project
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Inhibition of cytochrome P450c17 reduces spinal astrocyte activation in a mouse model of neuropathic pain via regulation of p38 MAPK phosphorylation
Choi, S. R., Beitz, A. J. & Lee, J. H., Oct 2019, In: Biomedicine and Pharmacotherapy. 118, 109299.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
nNOS-PSD95 interactions activate the PKC-ε isoform leading to increased GluN1 phosphorylation and the development of neuropathic mechanical allodynia in mice
Choi, S. R., Han, H. J., Beitz, A. J. & Lee, J. H., Jun 11 2019, In: Neuroscience Letters. 703, p. 156-161 6 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Spinal interleukin-1β inhibits astrocyte cytochrome P450c17 expression which controls the development of mechanical allodynia in a mouse model of neuropathic pain
Choi, S. R., Han, H. J., Beitz, A. J. & Lee, J. H., Jun 21 2019, In: Frontiers in Molecular Neuroscience. 12, 153.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations