Pharmacy Research and Graduate Education

Kyzer, J. L., Noman, M. A. A., Cuellar, R. A. D., Chung, S. S. W., Maitra, S., Naqvi, T., Hawkinson, J. E., Wolgemuth, D. J. & Georg, G. I., Jul 2023, In: Archiv der Pharmazie. 356, 7, 2300031.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Long-term reversal of chronic pain behavior in rodents through elevation of spinal agmatine

Peterson, C. D., Waataja, J. J., Kitto, K. F., Erb, S. J., Verma, H., Schuster, D. J., Churchill, C. C., Riedl, M. S., Belur, L. R., Wolf, D. A., McIvor, R. S., Vulchanova, L., Wilcox, G. L. & Fairbanks, C. A., Apr 5 2023, In: Molecular Therapy. 31, 4, p. 1123-1135 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Strategies for developing retinoic acid receptor alpha-selective antagonists as novel agents for male contraception

Al Noman, M. A., Cuellar, R. A. D., Kyzer, J. L., Chung, S. S. W., Cheryala, N., Holth, T. A. D., Maitra, S., Naqvi, T., Wong, H. L., Schönbrunn, E., Hawkinson, J. E., Wolgemuth, D. J. & Georg, G. I., Dec 5 2023, In: European Journal of Medicinal Chemistry. 261, 115821.

Research output: Contribution to journal › Article › peer-review

The opioid receptor: emergence through millennia of pharmaceutical sciences

Fairbanks, C. A. & Peterson, C. D., 2023, In: Frontiers in Pain Research. 4, 960389.

Research output: Contribution to journal › Short survey › peer-review

Open Access

2022

Central Nervous System Distribution of an Opioid Agonist Combination with Synergistic Activity

Griffith, J. I., Kim, M., Bruce, D. J., Peterson, C. D., Kitto, K. F., Mohammad, A. S., Rathi, S., Fairbanks, C. A., Wilcox, G. L. & Elmquist, W. F., Jan 1 2022, In: Journal of Pharmacology and Experimental Therapeutics. 380, 1, p. 34-46 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Targeting the somatosensory system with AAV9 and AAV2retro viral vectors

Skorput, A. G. J., Gore, R., Schorn, R., Riedl, M. S., de Velasco, E. M. F., Hadlich, B., Kitto, K. F., Fairbanks, C. A. & Vulchanova, L., Mar 2022, In: PloS one. 17, 3 March, e0264938.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

2021

Agmatine requires GluN2B-containing NMDA receptors to inhibit the development of neuropathic pain

Peterson, C. D., Kitto, K. F., Verma, H., Pflepsen, K., Delpire, E., Wilcox, G. L. & Fairbanks, C. A., 2021, In: Molecular Pain. 17

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Biodistribution of Adeno-Associated Virus Serotype 5 Viral Vectors following Intrathecal Injection

Pflepsen, K. R., Peterson, C. D., Kitto, K. F., Riedl, M. S., McIvor, R. S., Wilcox, G. L., Vulchanova, L. & Fairbanks, C. A., Oct 4 2021, In: Molecular pharmaceutics. 18, 10, p. 3741-3749 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Comparative Effectiveness of Intracerebroventricular, Intrathecal, and Intranasal Routes of AAV9 Vector Administration for Genetic Therapy of Neurologic Disease in Murine Mucopolysaccharidosis Type I

Belur, L. R., Romero, M., Lee, J., Podetz-Pedersen, K. M., Nan, Z., Riedl, M. S., Vulchanova, L., Kitto, K. F., Fairbanks, C. A., Kozarsky, K. F., Orchard, P. J., Frey, W. H., Low, W. C. & McIvor, R. S., May 10 2021, In: Frontiers in Molecular Neuroscience. 14, 618360.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Expression of and correlational patterns among neuroinflammatory, neuropeptide, and neuroendocrine molecules from cerebrospinal fluid in cerebral palsy

Goracke-Postle, C. J., Burkitt, C. C., Panoskaltsis-Mortari, A., Ehrhardt, M., Wilcox, G. L., Graupman, P., Partington, M. & Symons, F. J., Dec 2021, In: BMC neurology. 21, 1, 384.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2020

Novel M₂-selective, G_i-biased agonists of muscarinic acetylcholine receptors

Randáková, A., Nelic, D., Ungerová, D., Nwokoye, P., Su, Q., Doležal, V., El-Fakahany, E. E., Boulos, J. & Jakubík, J., May 1 2020, In: British Journal of Pharmacology. 177, 9, p. 2073-2089 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Partial Dehydration of Levothyroxine Sodium Pentahydrate in a Drug Product Environment: Structural Insights into Stability

Kaur, N., Young, V. G., Su, Y. & Suryanarayanan, R., Oct 5 2020, In: Molecular pharmaceutics. 17, 10, p. 3915-3929 15 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Profound tabletability deterioration of microcrystalline cellulose by magnesium stearate

Dun, J., Chen, H. & Sun, C. C., Nov 30 2020, In: International journal of pharmaceutics. 590, 119927.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Sustained-release buprenorphine induces acute opioid tolerance in the mouse

Larson, C. M., Peterson, C. D., Kitto, K. F., Wilcox, G. L. & Fairbanks, C. A., Oct 15 2020, In: European Journal of Pharmacology. 885, 173330.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2019

AAV-mediated gene delivery to the enteric nervous system by intracolonic injection

Gore, R., Riedl, M. S., Kitto, K. F., Fairbanks, C. A. & Vulchanova, L., 2019, Methods in Molecular Biology. Humana Press Inc., p. 407-415 9 p. (Methods in Molecular Biology; vol. 1950).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

4 Scopus citations

AAV-mediated gene delivery to the spinal cord by intrathecal injection

Peterson, C. D., Skorput, A. G. J., Kitto, K. F., Wilcox, G. L., Vulchanova, L. & Fairbanks, C. A., 2019, Methods in Molecular Biology. Humana Press Inc., p. 199-207 9 p. (Methods in Molecular Biology; vol. 1950).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Scopus citations

Agmatine preferentially antagonizes GluN2B-containing N-methyl-D-aspartate receptors in spinal cord

Waataja, J. J., Peterson, C. D., Verma, H., Goracke-Postle, C. J., Séguéla, P., Delpire, E., Wilcox, G. L. & Fairbanks, C. A., Feb 2019, In: Journal of neurophysiology. 121, 2, p. 662-671 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Analysis of equilibrium binding of an orthosteric tracer and two allosteric modulators

Jakubík, J., Randáková, A., El-Fakahany, E. E. & Doležal, V., Mar 2019, In: PloS one. 14, 3, e0214255.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Combination of a δ-opioid Receptor Agonist and Loperamide Produces Peripherally-mediated Analgesic Synergy in Mice

Bruce, D. J., Peterson, C. D., Kitto, K. F., Akgün, E., Lazzaroni, S., Portoghese, P. S., Fairbanks, C. A. & Wilcox, G. L., Sep 1 2019, In: Anesthesiology. 131, 3, p. 649-663 15 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Defining and Managing Pain in Stroke and Traumatic Brain Injury Research

Larson, C. M., Wilcox, G. L. & Fairbanks, C. A., Dec 1 2019, In: Comparative Medicine. 69, 6, p. 510-519 10 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Detailed method for intrathecal delivery of gene therapeutics by direct lumbar puncture in mice

Pflepsen, K. R., Peterson, C. D., Kitto, K. F., Vulchanova, L., Wilcox, G. L. & Fairbanks, C. A., 2019, Methods in Molecular Biology. Humana Press Inc., p. 305-312 8 p. (Methods in Molecular Biology; vol. 1937).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

8 Scopus citations

Direct Compression Tablet Containing 99% Active Ingredient—A Tale of Spherical Crystallization

Chen, H., Aburub, A. & Sun, C. C., Apr 2019, In: Journal of Pharmaceutical Sciences. 108, 4, p. 1396-1400 5 p.

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Identification and Screening of Selective WEE2 Inhibitors to Develop Non-Hormonal Contraceptives that Specifically Target Meiosis

Hanna, C. B., Yao, S., Martin, M., Schönbrunn, E., Georg, G. I., Jensen, J. T. & Cuellar, R. A. D., Dec 6 2019, In: ChemistrySelect. 4, 45, p. 13363-13369 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Inhibition of HINT1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice

Shah, R. M., Peterson, C., Strom, A., Dillenburg, M., Finzel, B., Kitto, K. F., Fairbanks, C., Wilcox, G. & Wagner, C. R., Oct 16 2019, In: ACS Chemical Neuroscience. 10, 10, p. 4385-4393 9 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

The Study of Pain in Rats and Mice

Larson, C. M., Wilcox, G. L. & Fairbanks, C. A., Dec 2019, In: Comparative Medicine. 69, 6, p. 555-570 16 p.

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

2018

Involvement of the VGF-derived peptide TLQP-62 in nerve injury induced hypersensitivity and spinal neuroplasticity

Skorput, A. G. J., Zhang, X., Waataja, J. J., Peterson, C. D., Riedl, M. S., Kitto, K. F., Truong, H., Huffman, C., Salton, S. R., Fairbanks, C. A., Honda, C. N. & Vulchanova, L., Sep 1 2018, In: Pain. 159, 9, p. 1802-1813 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Screening serine/threonine and tyrosine kinase inhibitors for histidine kinase inhibition

Wilke, K. E., Fihn, C. A. & Carlson, E. E., Oct 15 2018, In: Bioorganic and Medicinal Chemistry. p. 5322-5326 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2017

Adherence to treatment guidelines: The association between stroke risk stratified comparing CHADS₂ and CHA₂DS₂-VASc score levels and warfarin prescription for adult patients with atrial fibrillation

Chapman, S. A., St Hill, C. A., Little, M. M., Swanoski, M. T., Scheiner, S. R., Ware, K. B. & Lutfiyya, M. N., Feb 11 2017, In: BMC Health Services Research. 17, 1, 127.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria

Guo, Z., Sevrioukova, I. F., Denisov, I. G., Zhang, X., Chiu, T. L., Thomas, D. G., Hanse, E. A., Cuellar, R. A. D., Grinkova, Y. V., Langenfeld, V. W., Swedien, D. S., Stamschror, J. D., Alvarez, J., Luna, F., Galván, A., Bae, Y. K., Wulfkuhle, J. D., Gallagher, R. I., Petricoin, E. F., Norris, B., & 17 othersFlory, C. M., Schumacher, R. J., O'Sullivan, M. G., Cao, Q., Chu, H., Lipscomb, J. D., Atkins, W. M., Gupta, K., Kelekar, A., Blair, I. A., Capdevila, J. H., Falck, J. R., Sligar, S. G., Poulos, T. L., Georg, G. I., Ambrose, E. & Potter, D. A., Oct 19 2017, In: Cell Chemical Biology. 24, 10, p. 1259-1275.e6

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

2016

Development of an interprofessional and interdisciplinary collaborative research practice for clinical faculty

Hager, K., St Hill, C., Prunuske, J., Swanoski, M., Anderson, G. & Lutfiyya, M. N., Mar 3 2016, In: Journal of interprofessional care. 30, 2, p. 265-267 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2015

An epidemiological analysis of potential associations between C-reactive protein, inflammation, and prostate cancer in the male US population using the 2009-2010 National Health and Nutrition Examination Survey (NHANES) data

St. Hill, C. A. & Lutfiyya, M. N., 2015, In: Frontiers in Chemistry. 3, AUG, 55.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2014

Changes in Membrane Cholesterol Differentially Influence Preferential and Non-preferential Signaling of the M1 and M3 Muscarinic Acetylcholine Receptors

Michal, P., El-Fakahany, E. E. & Doležal, V., May 13 2014, In: Neurochemical Research. 40, 10, p. 2068-2077 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Long-term activation upon brief exposure to xanomleline is unique to M ₁and M₄ subtypes of muscarinic acetylcholine receptors

Sǎntrů̌ckóva, E., Doležal, V., El-Fakahany, E. E. & Jakubiḱ, J., Feb 18 2014, In: PloS one. 9, 2, e88910.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Molecular mechanisms of methoctramine binding and selectivity at muscarinic acetylcholine receptors

Jakubík, J., Zimčík, P., Randáková, A., Fuksová, K., El-Fakahany, E. E. & Doležal, V., Aug 2014, In: Molecular Pharmacology. 86, 2, p. 180-192 13 p.

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Outline of therapeutic interventions with muscarinic receptor-mediated transmission

Jakubík, J., Šantrůcková, E., Randáková, A., Janíčková, H., Zimčík, P., Rudajev, V., Michal, P., El-Fakahany, E. E. & Doležal, V., Mar 10 2014, In: Physiological Research. 63, SUPPL., p. S177-S189

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

2013

Uncoupling of M1 muscarinic receptor/G-protein interaction by amyloid β_1-42

Janíčková, H., Rudajev, V., Zimčík, P., Jakubík, J., Tanila, H., El-Fakahany, E. E. & Doležal, V., Apr 2013, In: Neuropharmacology. 67, p. 272-283 12 p.

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

2011

Negative cooperativity in binding of muscarinic receptor agonists and GDP as a measure of agonist efficacy

Jakubík, J., Janíčková, H., El-Fakahany, E. E. & Doležal, V., Mar 2011, In: British Journal of Pharmacology. 162, 5, p. 1029-1044 16 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

2007

Agmatine transport into spinal nerve terminals is modulated by polyamine analogs

Goracke-Postle, C. J., Overland, A. C., Stone, L. S. & Fairbanks, C. A., Jan 2007, In: Journal of Neurochemistry. 100, 1, p. 132-141 10 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Potassium- and capsaicin-induced release of agmatine from spinal nerve terminals

Goracke-Postle, C. J., Overland, A. C., Riedl, M. S., Stone, L. S. & Fairbanks, C. A., Sep 2007, In: Journal of Neurochemistry. 102, 6, p. 1738-1748 11 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

ST91 [2-(2,6-diethylphenylamino)-2-imidazoline hydrochloride]-mediated spinal antinociception and synergy with opioids persists in the absence of functional α-2A- or α-2C-adrenergic receptors

Stone, L. S., Kitto, K. F., Eisenach, J. C., Fairbanks, C. A. & Wilcox, G. L., Dec 2007, In: Journal of Pharmacology and Experimental Therapeutics. 323, 3, p. 899-906 8 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

2006

Release of tritiated agmatine from spinal synaptosomes

Goracke-Postle, C. J., Nguyen, H. O. X., Stone, L. S. & Fairbanks, C. A., Jan 2006, In: Neuroreport. 17, 1, p. 13-17 5 p.

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Supraspinally administered agmatine prevents the development of supraspinal morphine analgesic tolerance

Kitto, K. F. & Fairbanks, C. A., Apr 24 2006, In: European Journal of Pharmacology. 536, 1-2, p. 133-137 5 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

2005

Pharmacodynamic and pharmacokinetic studies of agmatine after spinal administration in the mouse

Roberts, J. C., Grocholski, B. M., Kitto, K. F. & Fairbanks, C. A., Sep 2005, In: Journal of Pharmacology and Experimental Therapeutics. 314, 3, p. 1226-1233 8 p.

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Transcutaneous electrical nerve stimulation activates peripherally located alpha-2A adrenergic receptors

King, E. W., Audette, K., Athman, G. A., Nguyen, H. O. X., Sluka, K. A. & Fairbanks, C. A., Jun 2005, In: Pain. 115, 3, p. 364-373 10 p.

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

2003

DPDPE-UK14,304 synergy is retained in mu opioid receptor knockout mice

Guo, X. H., Fairbanks, C. A., Stone, L. S. & Loh, H. H., Jul 2003, In: Pain. 104, 1-2, p. 209-217 9 p.

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Pharmacy Research and Graduate Education

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