Alexandra Sobeck

Associate Professor, Molecular Biology (BMBB)
Assistant Professor, Biochemistry, Molecular Biology, and Biophysics (TMED)

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Expertise related to UN SDGs

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

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2 Active
5 Finished

Genetic mechanisms of Mitotic DNA synthesis in mammalian cells
Shima, N., Bielinsky, A. K. & Sobeck, A.
NIH NIGMS NATL INST OF GENERAL
9/1/20 → 6/30/24
Project: Research project
Functional crosstalk between the Fanconi Anemia and ATRX/DAXX histone chaperone pathways
Sobeck, A.
NIH NIGMS NATL INST OF GENERAL
5/1/19 → 4/30/23
Project: Research project
The Role of EMSY in the FA DNA repair pathway
Sobeck, A.
NIH NATIONAL CANCER INSTITUTE (NCI)
4/1/16 → 3/31/18
Project: Research project
Roles of the Fanconi Anemia protein FANCD2 in DNA replic
Sobeck, A.
AMERICAN CANCER SOCIETY, INC.
1/1/13 → 12/31/16
Project: Research project
Molecular mechanisms for maintaining genome stabili
Sobeck, A.
National Science Foundation
12/1/11 → 11/30/15
Project: Research project

22 Article
1 Chapter

Functional cross talk between the Fanconi anemia and ATRX/DAXX histone chaperone pathways promotes replication fork recovery
Raghunandan, M., Yeo, J. E., Walter, R., Saito, K., Harvey, A. J., Ittershagen, S., Lee, E. A., Yang, J., Hoatlin, M. E., Bielinsky, A. K., Hendrickson, E. A., Schärer, O. & Sobeck, A., May 8 2020, In: Human molecular genetics. 29, 7, p. 1083-1095 13 p.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10
Paulson, C. N., John, K., Baxley, R. M., Kurniawan, F., Orellana, K., Francis, R., Sobeck, A., Eichman, B. F., Chazin, W. J., Aihara, H., Georg, G. I., Hawkinson, J. E. & Bielinsky, A. K., Aug 1 2019, In: Open biology. 9, 8, 190117.
Research output: Contribution to journal › Article › peer-review

Open Access
3 Scopus citations
FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response
Thompson, E. L., Yeo, J. E., Lee, E. A., Kan, Y., Raghunandan, M., Wiek, C., Hanenberg, H., Schärer, O. D., Hendrickson, E. A. & Sobeck, A., Nov 16 2017, In: Nucleic acids research. 45, 20, p. 11837-11857 21 p.
Research output: Contribution to journal › Article › peer-review

Open Access
11 Scopus citations
FANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex
Raghunandan, M., Chaudhury, I., Kelich, S. L., Hanenberg, H. & Sobeck, A., Feb 1 2015, In: Cell Cycle. 14, 3, p. 342-353 12 p.
Research output: Contribution to journal › Article › peer-review
38 Scopus citations
FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2
Castella, M., Jacquemont, C., Thompson, E. L., Yeo, J. E., Cheung, R. S., Huang, J. W., Sobeck, A., Hendrickson, E. A. & Taniguchi, T., 2015, In: PLoS genetics. 11, 10, e1005563.
Research output: Contribution to journal › Article › peer-review
43 Scopus citations