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Daniel L Mueller

MD, Professor, Director Rheumatic and Autoimmune Diseases

1989 …2020

Research activity per year

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Personal profile

Personal profile

I am currently a Professor of Medicine and Director of Rheumatic and Autoimmune Diseases. I am also a Core Faculty member within the Center for Immunology, where I lead its Center for Autoimmune Diseases Research Program. Finally, I am an active clinician in the practice of Rheumatology, with a focus on inflammatory arthritis. I hold the John F. Finn Arthritis Foundation Land Grant Chair.

My research program examines the regulation of CD4 T cell and B cell antigen responsiveness and immune self-tolerance in individuals prone to the development of autoimmune arthritis. This includes the investigation of CD4 T cell anergy induction and Foxp3+ Treg cell generation in mouse models of arthritis (Martinez RJ et al.; Taylor JJ et al.; Kalekar L et al.), as well investigations of self-antigen driven B cell activation, Ig gene recombination, and differentiation in humans with rheumatoid arthritis (Lloyd KA et al.; Steen J. et al.; Titcombe PJ et al.).

Expertise related to UN SDGs

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research interests

  • Immunological Tolerance
  • Rheumatology


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