Research output per year
Research output per year
- 1 - 50 out of 82 results
Search results
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2023
BATF represses BIM to sustain tolerant T cells in the periphery
Titcombe, P. J., Morales, M. S., Zhang, N. & Mueller, D. L., Dec 4 2023, In: Journal of Experimental Medicine. 220, 12, e20230183.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
2022
Immune tolerance of food is mediated by layers of CD4+ T cell dysfunction
Hong, S. W., Krueger, P. D., Osum, K. C., Dileepan, T., Herman, A., Mueller, D. L. & Jenkins, M. K., Jul 28 2022, In: Nature. 607, 7920, p. 762-768 7 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
2020
Different Hierarchies of Anti–Modified Protein Autoantibody Reactivities in Rheumatoid Arthritis
Sahlström, P., Hansson, M., Steen, J., Amara, K., Titcombe, P. J., Forsström, B., Stålesen, R., Israelsson, L., Piccoli, L., Lundberg, K., Klareskog, L., Mueller, D. L., Catrina, A. I., Skriner, K., Malmström, V. & Grönwall, C., Oct 1 2020, In: Arthritis and Rheumatology. 72, 10, p. 1643-1657 15 p.Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance
ElTanbouly, M. A., Zhao, Y., Nowak, E., Li, J., Schaafsma, E., Le Mercier, I., Ceeraz, S., Lines, J. L., Peng, C., Carriere, C., Huang, X., Day, M., Koehn, B., Lee, S. W., Morales, M. S., Hogquist, K. A., Jameson, S. C., Mueller, D., Rothstein, J., Blazar, B. R., & 2 others, Jan 17 2020, In: Science. 367, 6475, eaay0524.Research output: Contribution to journal › Article › peer-review
Open Access139 Scopus citations -
2019
Adenosine 2a Receptor Signal Blockade of Murine Autoimmune Arthritis via Inhibition of Pathogenic Germinal Center–Follicular Helper T Cells
Schmiel, S. E., Kalekar, L. A., Zhang, N., Blankespoor, T. W., Robinson, L. J. & Mueller, D. L., May 2019, In: Arthritis and Rheumatology. 71, 5, p. 773-783 11 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Alum adjuvant is more effective than MF59 at prompting early germinal center formation in response to peptide-protein conjugates and enhancing efficacy of a vaccine against opioid use disorders
Robinson, C., Baehr, C., Schmiel, S. E., Accetturo, C., Mueller, D. L. & Pravetoni, M., Apr 3 2019, In: Human Vaccines and Immunotherapeutics. 15, 4, p. 909-917 9 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Differential ACPA binding to nuclear antigens reveals a PAD-independent pathway and a distinct subset of acetylation cross-reactive autoantibodies in rheumatoid arthritis
Lloyd, K. A., Wigerblad, G., Sahlström, P., Garimella, M. G., Chemin, K., Steen, J., Titcombe, P. J., Marklein, B., Zhou, D., Stålesen, R., Ossipova, E., Lundqvist, C., Ekwall, O., Rönnelid, J., Mueller, D. L., Karlsson, M. C. I., Kaplan, M. J., Skriner, K., Klareskog, L., Wermeling, F., & 2 others, 2019, In: Frontiers in immunology. 10, JAN, 3033.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
Recognition of Amino Acid Motifs, Rather Than Specific Proteins, by Human Plasma Cell–Derived Monoclonal Antibodies to Posttranslationally Modified Proteins in Rheumatoid Arthritis
Steen, J., Forsström, B., Sahlström, P., Odowd, V., Israelsson, L., Krishnamurthy, A., Badreh, S., Mathsson Alm, L., Compson, J., Ramsköld, D., Ndlovu, W., Rapecki, S., Hansson, M., Titcombe, P. J., Bang, H., Mueller, D. L., Catrina, A. I., Grönwall, C., Skriner, K., Nilsson, P., & 3 others, Feb 2019, In: Arthritis and Rheumatology. 71, 2, p. 196-209 14 p.Research output: Contribution to journal › Article › peer-review
Open Access87 Scopus citations -
2018
Anergy into T regulatory cells: An integration of metabolic cues and epigenetic changes at the Foxp3 conserved non-coding sequence 2.
Silva Morales, M. & Mueller, D. L., 2018, In: F1000Research. 7, 1938.Research output: Contribution to journal › Review article › peer-review
Open Access8 Scopus citations -
Pathogenic Citrulline-Multispecific B Cell Receptor Clades in Rheumatoid Arthritis
Titcombe, P. J., Wigerblad, G., Sippl, N., Zhang, N., Shmagel, A. K., Sahlström, P., Zhang, Y., Barsness, L. O., Ghodke-Puranik, Y., Baharpoor, A., Hansson, M., Israelsson, L., Skriner, K., Niewold, T. B., Klareskog, L., Svensson, C. I., Amara, K., Malmström, V. & Mueller, D. L., Dec 2018, In: Arthritis and Rheumatology. 70, 12, p. 1933-1945 13 p.Research output: Contribution to journal › Article › peer-review
Open Access60 Scopus citations -
Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: Implications for B-cell selection
Lloyd, K. A., Steen, J., Amara, K., Titcombe, P. J., Israelsson, L., Lundström, S. L., Zhou, D., Zubarev, R. A., Reed, E., Piccoli, L., Gabay, C., Lanzavecchia, A., Baeten, D., Lundberg, K., Mueller, D. L., Klareskog, L., Malmström, V. & Grönwall, C., Jun 2018, In: European Journal of Immunology. 48, 6, p. 1030-1045 16 p.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
2017
Cutting edge: Adenosine a2a receptor signals inhibit germinal center T follicular helper cell differentiation during the primary response to vaccination
Schmiel, S. E., Yang, J. A., Jenkins, M. K. & Mueller, D. L., Jan 15 2017, In: Journal of Immunology. 198, 2, p. 623-628 6 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Relationship between CD4 regulatory T cells and anergy in vivo
Kalekar, L. A. & Mueller, D. L., Apr 1 2017, In: Journal of Immunology. 198, 7, p. 2527-2533 7 p.Research output: Contribution to journal › Review article › peer-review
Open Access60 Scopus citations -
Role of bone marrow-derived CD11c+ dendritic cells in systolic overload-induced left ventricular inflammation, fibrosis and hypertrophy
Wang, H., Kwak, D., Fassett, J., Liu, X., Yao, W., Weng, X., Xu, X., Xu, Y., Bache, R. J., Mueller, D. L. & Chen, Y., May 1 2017, In: Basic research in cardiology. 112, 3, 25.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
2016
CD4+ T cell anergy prevents autoimmunity and generates regulatory T cell precursors
Kalekar, L. A., Schmiel, S. E., Nandiwada, S. L., Lam, W. Y., Barsness, L. O., Zhang, N., Stritesky, G. L., Malhotra, D., Pauken, K. E., Linehan, J. L., O'Sullivan, G., Fife, B. T., Hogquist, K. A., Jenkins, M. & Mueller, D. L., Feb 1 2016, In: Nature immunology. 17, 3, p. 304-314 11 p.Research output: Contribution to journal › Article › peer-review
Open Access158 Scopus citations -
2015
The frequency of naive and early-activated hapten-specific B cell subsets dictates the efficacy of a therapeutic vaccine against prescription opioid abuse
Laudenbach, M., Baruffaldi, F., Vervacke, J. S., Distefano, M. D., Titcombe, P. J., Mueller, D. L., Tubo, N. J., Griffith, T. S. & Pravetoni, M., Jun 15 2015, In: Journal of Immunology. 194, 12, p. 5926-5936 11 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
2013
Cutting edge: Type 1 diabetes occurs despite robust anergy among endogenous insulin-specific CD4 T cells in NOD mice
Pauken, K. E., Linehan, J. L., Spanier, J. A., Sahli, N. L., Kalekar, L. A., Binstadt, B. A., Moon, J. J., Mueller, D. L., Jenkins, M. K. & Fife, B. T., Nov 15 2013, In: Journal of Immunology. 191, 10, p. 4913-4917 5 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Macrophage scavenger receptor 1 (Msr1, SR-A) Influences b cell autoimmunity by regulating soluble autoantigen concentration
Haasken, S., Auger, J. L., Taylor, J. J., Hobday, P. M., Goudy, B. D., Titcombe, P. J., Mueller, D. L. & Binstadt, B. A., Aug 1 2013, In: Journal of Immunology. 191, 3, p. 1055-1062 8 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Murine thymic selection quantified using a unique method to capture deleted T cells
Stritesky, G. L., Xing, Y., Erickson, J. R., Kalekar, L. A., Wang, X., Mueller, D. L., Jameson, S. C. & Hogquist, K. A., Mar 19 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 12, p. 4679-4684 6 p.Research output: Contribution to journal › Article › peer-review
Open Access137 Scopus citations -
2012
Arthritogenic self-reactive CD4 + T cells acquire an FR4 hiCD73 hi anergic state in the presence of foxp3 + regulatory t cells
Martinez, R. J., Zhang, N., Thomas, S. R., Nandiwada, S. L., Jenkins, M., Binstadt, B. A. & Mueller, D. L., Jan 1 2012, In: Journal of Immunology. 188, 1, p. 170-181 12 p.Research output: Contribution to journal › Article › peer-review
Open Access72 Scopus citations -
Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen
Taylor, J. J., Martinez, R. J., Titcombe, P. J., Barsness, L. O., Thomas, S. R., Zhang, N., Katzman, S. D., Jenkins, M. & Mueller, D. L., Oct 2012, In: Journal of Experimental Medicine. 209, 11, p. 2065-2077 13 p.Research output: Contribution to journal › Article › peer-review
95 Scopus citations -
2011
On the trail of arthritogenic T cells
Jenkins, M. K. & Mueller, D., Oct 2011, In: Arthritis and rheumatism. 63, 10, p. 2851-2853 3 p.Research output: Contribution to journal › Editorial › peer-review
2 Scopus citations -
Pregnancy and rheumatoid arthritis: Insights into the immunology of fetal tolerance and control of autoimmunity
Amin, S., Peterson, E. J., Reed, A. M. & Mueller, D. L., Oct 2011, In: Current rheumatology reports. 13, 5, p. 449-455 7 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
2010
Mechanisms maintaining peripheral tolerance
Mueller, D. L., Jan 2010, In: Nature immunology. 11, 1, p. 21-27 7 p.Research output: Contribution to journal › Review article › peer-review
339 Scopus citations -
2009
Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memory
Agarwal, P., Raghavan, A., Nandiwada, S. L., Curtsinger, J. M., Bohjanen, P. R., Mueller, D. L. & Mescher, M. F., Aug 1 2009, In: Journal of Immunology. 183, 3, p. 1695-1704 10 p.Research output: Contribution to journal › Article › peer-review
170 Scopus citations -
2008
Casitas B-lineage lymphoma b inhibits antigen recognition and slows cell cycle progression at late times during CD4+ T cell clonal expansion
Zhang, R., Zhang, N. & Mueller, D. L., 2008, In: Journal of Immunology. 181, 8, p. 5331-5339 9 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Langerhans cells are not required for efficient skin graft rejection
Obhrai, J. S., Oberbarnscheidt, M., Zhang, N., Mueller, D. L., Shlomchik, W. D., Lakkis, F. G., Shlomchik, M. J. & Kaplan, D. H., Aug 2008, In: Journal of Investigative Dermatology. 128, 8, p. 1950-1955 6 p.Research output: Contribution to journal › Article › peer-review
56 Scopus citations -
Proliferating CD4+ T cells undergo immediate growth arrest upon cessation of TCR signaling in vivo
Yarke, C. A., Dalheimer, S. L., Zhang, N., Catron, D. M., Jenkins, M. & Mueller, D. L., Jan 1 2008, In: Journal of Immunology. 180, 1, p. 156-162 7 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
2007
Allopeptide-specific CD4+ T cells facilitate the differentiation of directly alloreactive graft-infiltrating CD8+ T cells
Richards, D. M., Zhang, N., Dalheimer, S. L. & Mueller, D. L., Oct 2007, In: American Journal of Transplantation. 7, 10, p. 2269-2278 10 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Molecular mechanisms supporting peripheral T cell tolerance: Potential therapeutic approaches to autoimmunity and allograft rejection
Mueller, D. L., Jun 2007, In: Seminars in Immunology. 19, 3, p. 139 1 p.Research output: Contribution to journal › Editorial › peer-review
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mTOR at the crossroads of T cell proliferation and tolerance
Mondino, A. & Mueller, D. L., Jun 2007, In: Seminars in Immunology. 19, 3, p. 162-172 11 p.Research output: Contribution to journal › Review article › peer-review
90 Scopus citations -
mTOR at the crossroads of T cell proliferation and tolerance
Mondino, A. & Mueller, D. L., Jun 2007, In: Seminars in Immunology. 19, 3, p. 162-172 11 p.Research output: Contribution to journal › Review article › peer-review
90 Scopus citations -
2006
CD25+Foxp3+ regulatory T cells facilitate CD4 + T cell clonal anergy induction during the recovery from lymphopenia
Vanasek, T. L., Nandiwada, S. L., Jenkins, M. & Mueller, D. L., May 15 2006, In: Journal of Immunology. 176, 10, p. 5880-5889 10 p.Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
Linking diacylglycerol kinase to T cell anergy
Mueller, D. L., Nov 2006, In: Nature immunology. 7, 11, p. 1132-1134 3 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
p300/cyclic AMP-responsive element binding-binding protein mediates transcriptional coactivation by the CD28 T cell costimulatory receptor
Nandiwada, S. L., Li, W., Zhang, R. & Mueller, D. L., Jul 1 2006, In: Journal of Immunology. 177, 1, p. 401-413 13 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Prolonged TCR/CD28 engagement drives IL-2-independent T cell clonal expansion through signaling mediated by the mammalian target of rapamycin
Colombetti, S., Basso, V., Mueller, D. L. & Mondino, A., Mar 1 2006, In: Journal of Immunology. 176, 5, p. 2730-2738 9 p.Research output: Contribution to journal › Article › peer-review
Open Access114 Scopus citations -
Sustained B7/CD28 interactions and resultant phosphatisylinositol 3-kinase activity maintain G1→S phase transitions at an optimal rate
Bonnevier, J. L., Yarke, C. A. & Mueller, D. L., Jun 2006, In: European Journal of Immunology. 36, 6, p. 1583-1597 15 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
2005
E3 ubiquitin ligases and their control of T cell autoreactivity
Bonnevier, J. L., Zhang, R. & Mueller, D. L., Dec 2005, In: Arthritis Research and Therapy. 7, 6, p. 233-242 10 p.Research output: Contribution to journal › Review article › peer-review
13 Scopus citations -
Gene expression profiling in murine obliterative airway disease
Lande, J. D., Dalheimer, S. L., Mueller, D. L., Hertz, M. I. & King, R. A., Sep 2005, In: American Journal of Transplantation. 5, 9, p. 2170-2184 15 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Sharing of class I MHC molecules between donor and host promotes the infiltration of allografts by mHAg-reactive CD8+ T cells
Dalheimer, S. L., Richards, D. M. & Mueller, D. L., Apr 2005, In: American Journal of Transplantation. 5, 4 I, p. 832-838 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
2004
E3 ubiquitin ligases as T cell anergy factors
Mueller, D. L., Sep 2004, In: Nature immunology. 5, 9, p. 883-890 8 p.Research output: Contribution to journal › Review article › peer-review
192 Scopus citations -
Indirect Minor Histocompatibility Antigen Presentation by Allograft Recipient Cells in the Draining Lymph Node Leads to the Activation and Clonal Expansion of CD4+ T Cells that Cause Obliterative Airways Disease
Richards, D. M., Dalheimer, S. L., Ehst, B. D., Vanasek, T. L., Jenkins, M., Hertz, M. I. & Mueller, D. L., Mar 15 2004, In: Journal of Immunology. 172, 6, p. 3469-3479 11 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
Visualizing the first 50 hr of the primary immune response to a soluble antigen
Catron, D. M., Itano, A. A., Pape, K. A., Mueller, D. L. & Jenkins, M., Sep 2004, In: Immunity. 21, 3, p. 341-347 7 p.Research output: Contribution to journal › Review article › peer-review
144 Scopus citations -
2003
Trachea Allograft Class I Molecules Directly Activate and Retain CD8 + T Cells That Cause Obliterative Airways Disease
Richards, D. M., Dalheimer, S. L., Hertz, M. I. & Mueller, D. L., Dec 15 2003, In: Journal of Immunology. 171, 12, p. 6919-6928 10 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Tuning the immune system: Competing positive and negative feedback loops
Mueller, D. L., Mar 1 2003, In: Nature immunology. 4, 3, p. 210-211 2 p.Research output: Contribution to journal › Comment/debate › peer-review
18 Scopus citations -
2002
Constitutive active p21ras enhances primary T cell responsiveness to Ca2+ signals without interfering with the induction of clonal anergy
Crespi, D., Massa, S., Basso, V., Colombetti, S., Mueller, D. L. & Mondino, A., Sep 2002, In: European Journal of Immunology. 32, 9, p. 2500-2509 10 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Cutting edge: B7/CD28 interactions regulate cell cycle progression independent of the strength of TCR signaling
Bonnevier, J. L. & Mueller, D. L., Dec 15 2002, In: Journal of Immunology. 169, 12, p. 6659-6663 5 p.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
2001
Antagonistic roles for CTLA-4 and the mammalian target of rapamycin in the regulation of clonal anergy: Enhanced cell cycle progression promotes recall antigen responsiveness
Vanasek, T. L., Khoruts, A., Zell, T. & Mueller, D. L., Nov 15 2001, In: Journal of Immunology. 167, 10, p. 5636-5644 9 p.Research output: Contribution to journal › Article › peer-review
Open Access74 Scopus citations -
CD28 signaling augments Elk-1-dependent transcription at the c-fos gene during antigen stimulation
Li, W., Whaley, C. D., Bonnevier, J. L., Mondino, A., Martin, M. E., Aagaard-Tillery, K. M. & Mueller, D. L., Jul 15 2001, In: Journal of Immunology. 167, 2, p. 827-835 9 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
In vivo activation of antigen-specific CD4 T cells
Jenkins, M., Khoruts, A., Ingulli, E., Mueller, D. L., McSorley, S. J., Lee Reinhardt, R., Itano, A. & Pape, K. A., 2001, In: Annual Review of Immunology. 19, p. 23-45 23 p.Research output: Contribution to journal › Review article › peer-review
403 Scopus citations