Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Linking ex vivo to in vivo patient-specific models of malignant peripheral nerve sheath tumors
Wood, D. K. & Largaespada, D. A.
1/1/24 → 12/31/26
Project: Research project
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Deconvoluting the Ewing sarcoma genetic program using ancestry-informed human iPSC modeling
Webber, B. R., Dutton, J. R., Largaespada, D. A. & Spector, L. G.
NIH NATIONAL CANCER INSTITUTE (NCI)
4/7/23 → 3/31/28
Project: Research project
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Mechanistic insight into genome stability pathways
UNIVERSITY OF VIRGINIA, NIH NIGMS NATL INST OF GENERAL
11/15/22 → 5/31/26
Project: Research project
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Radiation Therapy and Myeloid-Derived Suppressor Cells: Breaking Down Their Cancerous Partnership
Bergerud, K. M. B., Berkseth, M., Pardoll, D. M., Ganguly, S., Kleinberg, L. R., Lawrence, J., Odde, D. J., Largaespada, D. A., Terezakis, S. A. & Sloan, L., 2024, (Accepted/In press) In: International Journal of Radiation Oncology Biology Physics.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
A Call for Discovery and Therapeutic Development for Cutaneous Neurofibromas
2022 NTAP Cutaneous Neurofibroma Symposium Participants, Aug 2023, In: Journal of Investigative Dermatology. 143, 8, p. 1351-1357 7 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon RB function in malignant peripheral nerve sheath tumors
Wang, J., Calizo, A., Zhang, L., Pino, J. C., Lyu, Y., Pollard, K., Zhang, X., Larsson, A. T., Conniff, E., Llosa, N. J., Wood, D. K., Largaespada, D. A., Moody, S. E., Gosline, S. J., Hirbe, A. C. & Pratilas, C. A., Nov 24 2023, In: Science Advances. 9, 47, p. eadg8876Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Combining nonsense mutation suppression therapy with nonsense-mediated decay inhibition in neurofibromatosis type 1
Osum, S. H., Oribamise, E. I., Corbière, S. M. A. S., Taisto, M., Jubenville, T., Coutts, A., Kirstein, M. N., Fisher, J., Moertel, C., Du, M., Bedwell, D., Largaespada, D. A. & Watson, A. L., Sep 12 2023, In: Molecular Therapy - Nucleic Acids. 33, p. 227-239 13 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Cutaneous Neurofibroma Heterogeneity: Factors that Influence Tumor Burden in Neurofibromatosis Type 1
Jiang, C., McKay, R. M., Lee, S. Y., Romo, C. G., Blakeley, J. O., Haniffa, M., Serra, E., Steensma, M. R., Largaespada, D. & Le, L. Q., Aug 2023, In: Journal of Investigative Dermatology. 143, 8, p. 1369-1377 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations
Press/Media
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HI’s new chief of staff looking to help build the Institute to even loftier heights
Elizabeth Fedie, Ann M Bode, Donna E Seabloom, Daniel F Voytas & David A Largaespada
7/15/20
1 item of Media coverage
Press/Media: Expert Comment