Projects per year
Personal profile
Research interests
I am a physician-scientist with a strong interest and a translational approach to investigation of solid tumor malignancies at the cellular and molecular level. As a fellowship-trained and practicing medical oncologist and neuro-oncologist, I have a strong interest in a ‘bedside-to-bench-and-back’ approach to translational oncology and laboratory research. At the national level, I served on the American Society of Clinical Oncology (ASCO) Scientific Committee for GI Cancers (2012-15). Identifying pertinent clinical problems in oncology that can be investigated in the laboratory setting is a high priority for our research program and collaborative efforts. I am board-certified in medical oncology, neuro-oncology, and internal medicine.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research interests
- intercellular communication
- cancer
- tumor microenvironment
- cancer cell biology
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Collaborations and top research areas from the last five years
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Leveraging low oxygen environments for improved Natural Killer cell immunotherapy
Kennedy, P., Felices, M., Lou, E., Luo, X. & Miller, J. S.
5/1/21 → 10/31/24
Project: Research project
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University of Minnesota Clinical Center for the Study of Pancreatic Disease
Bellin, M. D., Armfield, M. A., Chinnakotla, S., Freeman, M. L., Lou, E., Schwarzenberg, S. J., Spilseth, B. D. & Trikudanathan, G. V.
NIH NATL INST OF DIABETES/DIG/KIDNEY DIS
9/3/20 → 6/30/25
Project: Research project
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TUMOR-AGNOSTIC PRECISION IMMUNOONCOLOGY AND SOMATIC TARGETING RATIONAL FOR YOU(TAPISTRY) PHASE II PLATFORM TRIAL (BO41932)
HOFFMANN-LA ROCHE PHARMACEUTICALS
6/9/20 → 6/30/25
Project: Research project
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Comparative Genomic Analysis of Pancreatic Acinar Cell Carcinoma (PACC) and Pancreatic Ductal Adenocarcinoma (PDAC) Unveils New Actionable Genomic Aberrations in PACC
Florou, V., Elliott, A., Bailey, M. H., Stone, D., Affolter, K., Soares, H. P., Nevala-Plagemann, C., Scaife, C., Walker, P., Korn, W. M., Lou, E., Shroff, R. T., Hosein, P. J. & Garrido-Laguna, I., Sep 1 2023, In: Clinical Cancer Research. 29, 17, p. 3408-3417 10 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Electrical properties of cancer cells: A next generation biophysical therapeutic target: Comment on “The distinguishing electrical properties of cancer cells” by Di Gregorio, Israel, Staelens, Tankel, Shankar, and Tuszyński
Sarkari, A. & Lou, E., Dec 2023, In: Physics of Life Reviews. 47, p. 110-112 3 p.Research output: Contribution to journal › Comment/debate › peer-review
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ERBB family fusions are recurrent and actionable oncogenic targets across cancer types
Schubert, L., Elliott, A., Le, A. T., Estrada-Bernal, A., Doebele, R. C., Lou, E., Borghaei, H., Demeure, M. J., Kurzrock, R., Reuss, J. E., Ou, S. H. I., Braxton, D. R., Thomas, C. A., Darabi, S., Korn, W. M., El-Deiry, W. S. & Liu, S. V., 2023, In: Frontiers in Oncology. 13, 1115405.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Immunotherapy Success for Microsatellite Stable Colorectal Cancers-Searching for the Horizon
Lou, E., May 18 2023, In: JAMA Oncology. 9, 5, p. 615-617 3 p.Research output: Contribution to journal › Comment/debate › peer-review
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Metastatic Prostate Cancers with BRCA2 versus ATM Mutations Exhibit Divergent Molecular Features and Clinical Outcomes
Hwang, J., Shi, X., Elliott, A., Arnoff, T. E., McGrath, J., Xiu, J., Walker, P., Bergom, H. E., Day, A., Ahmed, S., Tape, S., Makovec, A., Ali, A., Shaker, R. M., Toye, E., Passow, R., Lozada, J. R., Wang, J., Lou, E., Mouw, K. W., & 7 others , Jul 2023, In: Clinical Cancer Research. 29, 14, p. 2702-2713 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Press/Media
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6 Colon Cancer Symptoms That Are Easily Overlooked
5/8/20
1 item of Media coverage
Press/Media: Expert Comment