Gyeoung-Jin Kang

2023

Ethacrynic acid suppresses B7-H4 expression involved in epithelial-mesenchymal transition of lung adenocarcinoma cells via inhibiting STAT3 pathway

Yu, L., Ji Kim, H., Kim, B., Jung Byun, H., Minh Nguyen, T., Ji Kim, E., Huy Phùng, H., Hyeon Kim, Y., Rahman, M., Yun Jang, J., Bae Rho, S., Jin Kang, G., Lee, H., Lee, K., Kyung Han, H., Kyung Park, M. & Hoon Lee, C., Jun 2023, In: Biochemical Pharmacology. 212, 115537.

Research output: Contribution to journal › Article › peer-review

Inflammatory Macrophage Interleukin-1β Mediates High-Fat Diet-Induced Heart Failure With Preserved Ejection Fraction

Liu, H., Huang, Y., Zhao, Y., Kang, G. J., Feng, F., Wang, X., Liu, M., Shi, G., Revelo, X., Bernlohr, D. & Dudley, S. C., Feb 2023, In: JACC: Basic to Translational Science. 8, 2, p. 174-185 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Lysosomal Ca²⁺ flux modulates automaticity in ventricular cardiomyocytes and correlates with arrhythmic risk

Xie, A., Kang, G. J., Kim, E. J., Feng, F., Givens, S. E., Ogle, B. M. & Dudley, S. C., Jun 1 2023, In: PNAS Nexus. 2, 6, pgad174.

Research output: Contribution to journal › Article › peer-review

Open Access

miR-448 regulates potassium voltage-gated channel subfamily A member 4 (KCNA4) in ischemia and heart failure

Kang, G. J., Xie, A., Kim, E. & Dudley, S. C., May 2023, In: Heart Rhythm. 20, 5, p. 730-736 7 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Targeting PERK to treat arrhythmias

Liu, M., Kang, G. J. & Dudley, S. C., Aug 2023, In: Trends in Molecular Medicine. 29, 8, p. 583 1 p.

Research output: Contribution to journal › Letter › peer-review

2022

Loss of EMP2 Inhibits Melanogenesis of MNT1 Melanoma Cells via Regulation of TRP-2

Enkhtaivan, E., Kim, H. J., Kim, B., Byun, H. J., Yu, L., Nguyen, T. M., Nguyen, T. H., Do, P. A., Kim, E. J., Kim, K. S., Huy, H. P., Rahman, M., Jang, J. Y., Rho, S. B., Lee, H., Kang, G. J., Park, M. K., Kim, N. H., Choi, C. I., Lee, K., & 4 othersHan, H. K., Cho, J., Lee, A. Y. & Lee, C. H., Mar 2022, In: Biomolecules and Therapeutics. 30, 2, p. 203-211 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Preventing unfolded protein response-induced ion channel dysregulation to treat arrhythmias

Liu, M., Kang, G. J. & Dudley, S. C., Jun 2022, In: Trends in Molecular Medicine. 28, 6, p. 443-451 9 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

5 Scopus citations

PRR16/Largen Induces Epithelial-Mesenchymal Transition through the Interaction with ABI2 Leading to the Activation of ABL1 Kinase

Kang, G. J., Park, J. H., Kim, H. J., Kim, E. J., Kim, B., Byun, H. J., Yu, L., Nguyen, T. M., Nguyen, T. H., Kim, K. S., Huy, H. P., Rahman, M., Kim, Y. H., Jang, J. Y., Park, M. K., Lee, H., Choi, C. I., Lee, K., Han, H. K., Cho, J., & 2 othersRho, S. B. & Lee, C. H., Jul 2022, In: Biomolecules and Therapeutics. 30, 4, p. 340-347 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Reduced sarcoplasmic reticulum Ca²⁺ pump activity is antiarrhythmic in ischemic cardiomyopathy

Xie, A., Liu, H., Kang, G. J., Feng, F. & Dudley, S. C., Dec 2022, In: Heart Rhythm. 19, 12, p. 2107-2114 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2021

Ethacrynic acid, a loop diuretic, suppresses epithelial-mesenchymal transition of A549 lung cancer cells via blocking of NDP-induced WNT signaling

Yu, L., Kim, H. J., Park, M. K., Byun, H. J., Kim, E. J., Kim, B., Nguyen, M. T., Kim, J. H., Kang, G. J., Lee, H., Kim, S. Y., Rho, S. B. & Lee, C. H., Jan 2021, In: Biochemical Pharmacology. 183, 114339.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Inhibition of the unfolded protein response reduces arrhythmia risk after myocardial infarction

Liu, M., Liu, H., Parthiban, P., Kang, G. J., Shi, G., Feng, F., Zhou, A., Gu, L., Karnopp, C., Tolkacheva, E. G. & Dudley, S. C., Sep 15 2021, In: Journal of Clinical Investigation. 131, 18, e147836.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Lw1497, an inhibitor of malate dehydrogenase, suppresses tgf-β1-induced epithelial-mesenchymal transition in lung cancer cells by downregulating slug

Kim, H. J., Park, M. K., Byun, H. J., Kim, M., Kim, B., Yu, L., Nguyen, T. M., Nguyen, T. H., Do, P. A., Kim, E. J., Kim, J. H., Enkhtaivan, E., Kim, K. S., Jang, J. Y., Kang, G. J., Lee, H., Won, M., Lee, K., Cho, J. & Lee, C. H., Nov 2021, In: Antioxidants. 10, 11, 1674.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Magnesium deficiency causes a reversible, metabolic, diastolic cardiomyopathy

Liu, M., Liu, H., Feng, F., Xie, A., Kang, G. J., Zhao, Y., Hou, C. R., Zhou, X. & Dudley, S. C., 2021, In: Journal of the American Heart Association. 10, 12, e020205.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Resolvin d1 suppresses h₂ o₂-induced senescence in fibroblasts by inducing autophagy through the mir-1299/arg2/arl1 axis

Kim, H. J., Kim, B., Byun, H. J., Yu, L., Nguyen, T. M., Nguyen, T. H., Do, P. A., Kim, E. J., Cheong, K. A., Kim, K. S., Phùng, H. H., Rahman, M., Jang, J. Y., Rho, S. B., Kang, G. J., Park, M. K., Lee, H., Lee, K., Cho, J., Han, H. K., & 3 othersKim, S. G., Lee, A. Y. & Lee, C. H., Dec 2021, In: Antioxidants. 10, 12, 1924.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

2020

MIR448 antagomir reduces arrhythmic risk after myocardial infarction by upregulating the cardiac sodium channel

Kang, G. J., Xie, A., Liu, H. & Dudley, S. C., Dec 3 2020, In: JCI Insight. 5, 23, e140759.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

SARNP, a participant in mRNA splicing and export, negatively regulates E-cadherin expression via interaction with pinin

Kang, G. J., Park, M. K., Byun, H. J., Kim, H. J., Kim, E. J., Yu, L., Kim, B., Shim, J. G., Lee, H. & Lee, C. H., Feb 1 2020, In: Journal of cellular physiology. 235, 2, p. 1543-1555 13 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Therapeutic effects of specialized pro-resolving lipids mediators on cardiac fibrosis via nrf2 activation

Kang, G. J., Kim, E. J. & Lee, C. H., Dec 2020, In: Antioxidants. 9, 12, p. 1-27 27 p., 1259.

Research output: Contribution to journal › Review article › peer-review

Open Access

19 Scopus citations

2019

YDJC Induces Epithelial-Mesenchymal Transition via Escaping from Interaction with CDC16 through Ubiquitination of PP2A

Kim, E. J., Park, M. K., Kang, G. J., Byun, H. J., Kim, H. J., Yu, L., Kim, B., Chae, H. S., Chin, Y. W., Shim, J. G., Lee, H. & Lee, C. H., 2019, In: Journal of Oncology. 2019, 3542537.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2018

HuR-mediated SCN5A messenger RNA stability reduces arrhythmic risk in heart failure

Zhou, A., Xie, A., Kim, T. Y., Liu, H., Shi, G., Kang, G. J., Jiang, N., Liu, M., Jeong, E. M., Choi, B. R. & Dudley, S. C., Jul 2018, In: Heart Rhythm. 15, 7, p. 1072-1080 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Over-activation of AKT signaling leading to 5-Fluorouracil resistance in SNU-C5/5-FU cells

Kim, E. J., Kang, G. J., Kang, J. I., Boo, H. J., Hyun, J. W., Koh, Y. S., Chang, W. Y., Kim, Y. R., Kwon, J. M., Maeng, Y. H., Yoo, E. S., Lee, C. H. & Kang, H. K., Apr 13 2018, In: Oncotarget. 9, 28, p. 19911-19928 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

RNA binding protein, HuR, regulates SCN5A expression through stabilizing MEF2C transcription factor mRNA

Zhou, A., Shi, G., Kang, G. J., Xie, A., Liu, H., Jiang, N., Liu, M., Jeong, E. M. & Dudley, S. C., May 1 2018, In: Journal of the American Heart Association. 7, 9, e007802.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

YdjC chitooligosaccharide deacetylase homolog induces keratin reorganization in lung cancer cells: Involvement of interaction between YDJC and CDC16

Kim, E. J., Park, M. K., Byun, H. J., Kang, G. J., Yu, L., Kim, H. J., Shim, J. G., Lee, H. & Lee, C. H., May 1 2018, In: Oncotarget. 9, 33, p. 22915-22928 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

2017

Novel involvement of miR-522-3p in high-mobility group box 1-induced prostaglandin reductase 1 expression and reduction of phagocytosis

Kang, G. J., Lee, H. J., Byun, H. J., Kim, E. J., Kim, H. J., Park, M. K. & Lee, C. H., Apr 1 2017, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1864, 4, p. 625-633 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Novel involvement of RhebL1 in sphingosylphosphorylcholineinduced keratin phosphorylation and reorganization: Binding to and activation of AKT1

Kim, H. J., Byun, H. J., Park, M. K., Kim, E. J., Kang, G. J. & Lee, C. H., 2017, In: Oncotarget. 8, 13, p. 20851-20864 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2016

Epithelial membrane protein 2 regulates sphingosylphosphorylcholine-induced keratin 8 phosphorylation and reorganization: Changes of PP2A expression by interaction with alpha4 and caveolin-1 in lung cancer cells

Lee, E. J., Park, M. K., Kim, H. J., Kim, E. J., Kang, G. J., Byun, H. J. & Lee, C. H., Jun 1 2016, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1863, 6, p. 1157-1169 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Leukotriene B4 induces EMT and vimentin expression in PANC-1 pancreatic cancer cells: Involvement of BLT2 via ERK2 activation

Kim, Y. R., Park, M. K., Kang, G. J., Kim, H. J., Kim, E. J., Byun, H. J., Lee, M. Y. & Lee, C. H., Dec 1 2016, In: Prostaglandins Leukotrienes and Essential Fatty Acids. 115, p. 67-76 10 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Novel effects of FTY720 on perinuclear reorganization of keratin network induced by sphingosylphosphorylcholine: Involvement of protein phosphatase 2A and G-protein-coupled receptor-12

Park, M. K., Park, S., Kim, H. J., Kim, E. J., Kim, S. Y., Kang, G. J., Byun, H. J., Kim, S. H., Lee, H. & Lee, C. H., Mar 15 2016, In: European Journal of Pharmacology. 775, p. 86-95 10 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Novel effects of sphingosylphosphorylcholine on invasion of breast cancer: Involvement of matrix metalloproteinase-3 secretion leading to WNT activation

Kim, H. J., Kang, G. J., Kim, E. J., Park, M. K., Byun, H. J., Nam, S., Lee, H. & Lee, C. H., Sep 1 2016, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1862, 9, p. 1533-1543 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

2015

Cardamonin suppresses TGF-β1-induced epithelial mesenchymal transition via restoring protein phosphatase 2A expression

Kim, E. J., Kim, H. J., Park, M. K., Kang, G. J., Byun, H. J., Lee, H., Lee, C. H. & Lee, C. H., Mar 1 2015, In: Biomolecules and Therapeutics. 23, 2, p. 141-148 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Dieckol, a component of ecklonia cava, suppresses the production of MDC/CCL22 via down-regulating STAT1 pathway in interferon-γ stimulated HaCaT human keratinocytes

Kang, N. J., Koo, D. H., Kang, G. J., Han, S. C., Lee, B. W., Koh, Y. S., Hyun, J. W., Lee, N. H., Ko, M. H., Kang, H. K. & Yoo, E. S., 2015, In: Biomolecules and Therapeutics. 23, 3, p. 238-244 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

Diphlorethohydroxycarmalol inhibits interleukin-6 production by regulating NF-κB, STAT5 and SOCS1 in lipopolysaccharide-stimulated RAW264.7 cells

Kang, N. J., Han, S. C., Kang, G. J., Koo, D. H., Koh, Y. S., Hyun, J. W., Lee, N. H., Ko, M. H., Kang, H. K. & Yoo, E. S., Apr 1 2015, In: Marine Drugs. 13, 4, p. 2141-2157 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

43 Scopus citations

Docosahexaenoic acid alleviates atopic dermatitis by generating tregs and IL-10/TGF-β-modified macrophages via a TGF-β-dependent mechanism

Han, S. C., Koo, D. H., Kang, N. J., Yoon, W. J., Kang, G. J., Kang, H. K. & Yoo, E. S., Jan 1 2015, In: Journal of Investigative Dermatology. 135, 6, p. 1556-1564 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

High-mobility group box 1 suppresses resolvin D1-induced phagocytosis via induction of resolvin D1-inactivating enzyme, 15-hydroxyprostaglandin dehydrogenase

Kang, G. J., Lee, H. J., Kang, Y. P., Kim, E. J., Kim, H. J., Byun, H. J., Park, M. K., Cho, H., Kwon, S. W. & Lee, C. H., Sep 1 2015, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1852, 9, p. 1981-1988 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

2014

Quercetagetin inhibits macrophage-derived chemokine in HaCaT human keratinocytes via the regulation of signal transducer and activator of transcription 1, suppressor of cytokine signalling 1 and transforming growth factor-β1

Kang, G. J., Han, S. C., Kang, N. J., Koo, D. H., Park, D. B., Eun, S. Y., Kang, H. K. & Yoo, E. S., Sep 1 2014, In: British Journal of Dermatology. 171, 3, p. 512-523 12 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

2013

Anti-inflammatory effect of quercetagetin, an active component of immature Citrus unshiu, in HaCaT human keratinocytes

Kang, G. J., Han, S. C., Ock, J. W., Kang, H. K. & Yoo, E. S., 2013, In: Biomolecules and Therapeutics. 21, 2, p. 138-145 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

Ceramium boydenii, a red alga, inhibits MDC/CCL22 production via suppression of STAT1 activation in HaCaT keratinocyte

Kang, N. J., Kang, G. J., Han, S. C., Hyun, E. A., Koo, D. H., Koh, Y. S., Ko, M. H., Hyun, J. W., Kang, H. K. & Yoo, E. S., 2013, In: Korean Journal of Pharmacognosy. 44, 2, p. 154-160 7 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Methyl 5-chloro-4,5-didehydrojasmonate (J7) inhibits macrophage- derived chemokine production via down-regulation of the signal transducers and activators of transcription 1 pathway in HaCaT human keratinocytes

Kang, G. J., Dang, H. T., Han, S. C., Kang, N. J., Koo, D. H., Koh, Y. S., Hyun, J. W., Kang, H. K., Jung, J. H. & Yoo, E. S., Oct 2013, In: Chemical and Pharmaceutical Bulletin. 61, 10, p. 1002-1008 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Sargaquinoic acid isolated from Sargassum siliquastrum inhibits lipopolysaccharide-induced nitric oxide production in macrophages via modulation of nuclear factor-κB and c-Jun N-terminal kinase pathways

Kang, G. J., Han, S. C., Yoon, W. J., Koh, Y. S., Hyun, J. W., Kang, H. K., Youl Cho, J. & Yoo, E. S., Feb 2013, In: Immunopharmacology and Immunotoxicology. 35, 1, p. 80-87 8 p.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

2012

Anti-inflammatory effect of sargachromanol G isolated from Sargassum siliquastrum in RAW 264.7 cells

Yoon, W. J., Heo, S. J., Han, S. C., Lee, H. J., Kang, G. J., Kang, H. K., Hyun, J. W., Koh, Y. S. & Yoo, E. S., Aug 2012, In: Archives of Pharmacal Research. 35, 8, p. 1421-1430 10 p.

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

Diphlorethohydroxycarmalol, isolated from Ishige okamurae, increases prostaglandin E₂ through the expression of cyclooxygenase-1 and -2 in HaCaT human keratinocytes

Kang, G. J., Han, S. C., Koh, Y. S., Kang, H. K., Jeon, Y. J. & Yoo, E. S., 2012, In: Biomolecules and Therapeutics. 20, 6, p. 520-525 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

External application of fermented olive flounder (Paralichthys Olivaceus) oil alleviates inflammatory responses in 2,4-dinitrochlorobenzene- induced atopic dermatitis mouse model

Han, S. C., Kang, G. J., Ko, Y. J., Kang, H. K., Moon, S. W., Ann, Y. S. & Yoo, E. S., 2012, In: Toxicological Research. 28, 3, p. 159-164 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Fermented fish oil suppresses T helper 1/2 cell response in a mouse model of atopic dermatitis via generation of CD4⁺CD25⁺Foxp3⁺ T cells

Han, S. C., Kang, G. J., Ko, Y. J., Kang, H. K., Moon, S. W., Ann, Y. S. & Yoo, E. S., Aug 9 2012, In: BMC Immunology. 13, 44.

Research output: Contribution to journal › Article › peer-review

Open Access

52 Scopus citations

In vitro stability and in vivo anti-inflammatory efficacy of synthetic jasmonates

Dang, H. T., Lee, Y. M., Kang, G. J., Yoo, E. S., Hong, J., Lee, S. M., Lee, S. K., Pyee, Y., Chung, H. J., Moon, H. R., Kim, H. S. & Jung, J. H., Jul 1 2012, In: Bioorganic and Medicinal Chemistry. 20, 13, p. 4109-4116 8 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Sargachromanol G regulates the expression of osteoclastogenic factors in human osteoblast-like MG-63 cells

Yoon, W. J., Heo, S. J., Han, S. C., Lee, H. J., Kang, G. J., Yang, E. J., Park, S. S., Kang, H. K. & Yoo, E. S., Sep 2012, In: Food and Chemical Toxicology. 50, 9, p. 3273-3279 7 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

The chloroform fraction of Carpinus tschonoskii leaves inhibits the production of inflammatory mediators in HaCaT keratinocytes and RAW264.7 macrophages

Kang, G. J., Kang, N. J., Han, S. C., Koo, D. H., Kang, H. K., Yoo, B. S. & Yoo, E. S., Dec 2012, In: Toxicological Research. 28, 4, p. 255-262 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

2011

Anti-inflammatory effect of methyl dehydrojasmonate (J2) is mediated by the NF-κB pathway

Lee, H. J., Maeng, K., Dang, H. T., Kang, G. J., Ryou, C., Jung, J. H., Kang, H. K., Prchal, J. T., Yoo, E. S. & Yoon, D., Jan 2011, In: Journal of Molecular Medicine. 89, 1, p. 83-90 8 p.

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Evaluation of endogenous fatty acid amides and their synthetic analogues as potential anti-inflammatory leads

Dang, H. T., Kang, G. J., Yoo, E. S., Hong, J., Choi, J. S., Kim, H. S., Chung, H. Y. & Jung, J. H., Feb 15 2011, In: Bioorganic and Medicinal Chemistry. 19, 4, p. 1520-1527 8 p.

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

The inhibitory effect of premature citrus unshiu extract on atopic dermatitis in vitro and in vivo

Kang, G. J., Han, S. C., Yi, E. J., Kang, H. K. & Yoo, E. S., Sep 2011, In: Toxicological Research. 27, 3, p. 173-180 8 p.

Research output: Contribution to journal › Short survey › peer-review

Open Access

17 Scopus citations

2010

Effects of horse bone extracts on the induced postmenopausal osteoporosis in rats

Park, S. S., Lee, H. J., Yoon, W. J., Kang, G. J., Yang, E. J., Kim, H. S., Choo, C. S., Kang, H. K. & Yoo, E. S., Sep 2010, In: Korean Journal of Pharmacognosy. 41, 3, p. 204-209 6 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

2009

Anti-Inflammatory effect of Dangyuja (Citrus grandis osbeck) Leaves in LPS-Stimulated RAW 264.7 Cells

Yang, E. J., Lee, H. J., Kang, G. J., Park, S. S., Yoon, W. J., Kang, H. K., Cho, S. K. & Yoo, E. S., Oct 2009, In: Food Science and Biotechnology. 18, 5, p. 1063-1070 8 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Gyeoung-Jin Kang

Research output

Search results