Projects per year
Personal profile
Education/Academic qualification
PhD, University of Minnesota Twin Cities
Award Date: Jul 31 2012
Research interests
- DNA damage
- DNA
- Nuclear
- Transcription
- Post translational modification
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Therapeutic targeting of R-loop response pathways in spliceosome mutant MDS
9/1/23 → 8/31/26
Project: Research project
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Delineating ATR response in U2AF1 mutant hematologic malignancies
AMERICAN ASSOCIATION FOR CANCER RESEARCH
7/1/22 → 6/30/25
Project: Research project
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Implications of PARP1 in myelodysplastic syndromes and targeted therapy
Nguyen, H. D., Sarver, A. L. & Zhang, L.
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
5/20/22 → 4/30/27
Project: Research project
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Functional characterization of mis-spliced ATR transcript in myelodysplastic syndromes
AMERICAN SOCIETY OF HEMATOLOGY
7/1/21 → 6/30/24
Project: Research project
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Summer Research at the University of Minnesota Medical S
Campbell, C. R., Henke, C. A. & Nguyen, H. D.
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
6/1/18 → 5/31/24
Project: Research project
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R-Loop Accumulation in Spliceosome Mutant Leukemias Confers Sensitivity to PARP1 Inhibition by Triggering Transcription–Replication Conflicts
Liu, Z. S., Sinha, S., Bannister, M., Song, A., Arriaga-Gomez, E., McKeeken, A. J., Bonner, E. A., Hanson, B. K., Sarchi, M., Takashima, K., Zong, D., Corral, V. M., Nguyen, E., Yoo, J., Chiraphapphaiboon, W., Leibson, C., McMahon, M. C., Rai, S., Swisher, E. M., Sachs, Z., & 10 others , 2024, In: Cancer Research. 84, 4, p. 577-597 21 p.Research output: Contribution to journal › Article › peer-review
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PARP1 associates with R-loops to promote their resolution and genome stability
Laspata, N., Kaur, P., Mersaoui, S. Y., Muoio, D., Liu, Z. S., Bannister, M. H., Nguyen, H. D., Curry, C., Pascal, J. M., Poirier, G. G., Wang, H., Masson, J. Y. & Fouquerel, E., Mar 21 2023, In: Nucleic acids research. 51, 5, p. 2215-2237 23 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Saracatinib synergizes with enzalutamide to downregulate AR activity in CRPC
White, R. E., Bannister, M., Day, A., Bergom, H. E., Tan, V. M., Hwang, J., Dang Nguyen, H. & Drake, J. M., 2023, In: Frontiers in Oncology. 13, 1210487.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of Formaldehyde-Induced DNA-RNA Cross-Links in the A/J Mouse Lung Tumorigenesis Model
Dator, R. P., Murray, K. J., Luedtke, M. W., Jacobs, F. C., Kassie, F., Nguyen, H. D., Villalta, P. W. & Balbo, S., Nov 21 2022, In: Chemical research in toxicology. 35, 11, p. 2025-2036 12 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
ATR Protects the Genome against R Loops through a MUS81-Triggered Feedback Loop
Matos, D. A., Zhang, J. M., Ouyang, J., Nguyen, H. D., Genois, M. M. & Zou, L., Feb 6 2020, In: Molecular Cell. 77, 3, p. 514-527.e4Research output: Contribution to journal › Article › peer-review
Open Access84 Scopus citations