Jill M Siegfried

2020

Anti-EGFR Fibronectin Bispecific Chemically Self-Assembling Nanorings (CSANs) Induce Potent T Cell-Mediated Antitumor Responses and Downregulation of EGFR Signaling and PD-1/PD-L1 Expression

Kilic, O., De Souza, M. R. M., Almotlak, A. A., Wang, Y., Siegfried, J. M., Distefano, M. D. & Wagner, C. R., Sep 24 2020, In: Journal of medicinal chemistry. 63, 18, p. 10235-10245 11 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Inhibiting Pathways Predicted From a Steroid Hormone Gene Signature Yields Synergistic Antitumor Effects in NSCLC

Almotlak, A. A., Farooqui, M. & Siegfried, J. M., Jan 2020, In: Journal of Thoracic Oncology. 15, 1, p. 62-79 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Prevention of tobacco carcinogen-induced lung tumor development by a novel stat3 decoy inhibitor

Njatcha, C., Farooqui, M., Almotlak, A. A. & Siegfried, J. M., Sep 1 2020, In: Cancer Prevention Research. 13, 9, p. 735-746 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

2019

Lung adenocarcinoma syndecan-2 potentiates cell invasiveness

Tsoyi, K., Osorio, J. C., Chu, S. G., Fernandez, I. E., De Frias, S. P., Sholl, L., Cui, Y., Tellez, C. S., Siegfried, J. M., Belinsky, S. A., Perrella, M. A., El-Chemaly, S. & Rosas, I. O., Jun 2019, In: American journal of respiratory cell and molecular biology. 60, 6, p. 659-666 8 p.

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

2018

Gene promoter hypermethylation detected in sputum predicts FEV₁ decline and all-cause mortality in smokers

Leng, S., Diergaarde, B., Picchi, M. A., Wilson, D. O., Gilliland, F. D., Yuan, J. M., Siegfried, J. M. & Belinsky, S. A., Jul 15 2018, In: American journal of respiratory and critical care medicine. 198, 2, p. 187-196 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Preclinical Evidence for Combined Use of Aromatase Inhibitors and NSAIDs as Preventive Agents of Tobacco-Induced Lung Cancer

Stabile, L. P., Farooqui, M., Kanterewicz, B., Abberbock, S., Kurland, B. F., Diergaarde, B. & Siegfried, J. M., Mar 2018, In: Journal of Thoracic Oncology. 13, 3, p. 399-412 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer

Garon, E. B., Siegfried, J. M., Stabile, L. P., Young, P. A., Marquez-Garban, D. C., Park, D. J., Patel, R., Hu, E. H., Sadeghi, S., Parikh, R. J., Reckamp, K. L., Adams, B., Elashoff, R. M., Elashoff, D., Grogan, T., Wang, H. J., Dacic, S., Brennan, M., Valdes, Y., Davenport, S., & 4 othersDubinett, S. M., Press, M. F., Slamon, D. J. & Pietras, R. J., Sep 2018, In: Lung Cancer. 123, p. 91-98 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

STAT3 cyclic decoy demonstrates robust antitumor effects in non–small cell lung cancer

Njatcha, C., Farooqui, M., Kornberg, A., Johnson, D. E., Grandis, J. R. & Siegfried, J. M., Sep 2018, In: Molecular Cancer Therapeutics. 17, 9, p. 1917-1926 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

31 Scopus citations

Status of agents targeting the HGF/c-Met axis in lung cancer

Miranda, O., Farooqui, M. & Siegfried, J. M., Sep 2018, In: Cancers. 10, 9, 280.

Research output: Contribution to journal › Review article › peer-review

Open Access

49 Scopus citations

2017

Clinical Utility of Chromosomal Aneusomy in Individuals at High Risk of Lung Cancer

Barón, A. E., Kako, S., Feser, W. J., Malinowski, H., Merrick, D., Garg, K., Malkoski, S., Pretzel, S., Siegfried, J. M., Franklin, W. A., Miller, Y., Wolf, H. J. & Varella-Garcia, M., Oct 2017, In: Journal of Thoracic Oncology. 12, 10, p. 1512-1523 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Gene methylation biomarkers in sputum as a classifier for lung cancer risk

Leng, S., Wu, G., Klinge, D. M., Thomas, C. L., Casas, E., Picchi, M. A., Stidley, C. A., Lee, S. J., Aisner, S., Siegfried, J. M., Ramalingam, S., Khuri, F. R., Karp, D. D. & Belinsky, S. A., 2017, In: Oncotarget. 8, 38, p. 63978-63985 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Interaction between the estrogen receptor and fibroblast growth factor receptor pathways in non-small cell lung cancer

Siegfried, J. M., Farooqui, M., Rothenberger, N. J., Dacic, S. & Stabile, L. P., 2017, In: Oncotarget. 8, 15, p. 24063-24076 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

KRAS and TP53 mutations in bronchoscopy samples from former lung cancer patients

Gao, W., Jin, J., Yin, J., Land, S., Gaither-Davis, A., Christie, N., Luketich, J. D., Siegfried, J. M. & Keohavong, P., Feb 1 2017, In: Molecular Carcinogenesis. 56, 2, p. 381-388 8 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Lung endothelial microRNA-1 regulates tumor growth and angiogenesis

Korde, A., Jin, L., Zhang, J. G., Ramaswamy, A., Hu, B., Kolahian, S., Guardela, B. J., Herazo-Maya, J., Siegfried, J. M., Stabile, L., Pisani, M. A., Herbst, R. S., Kaminski, N., Elias, J. A., Puchalski, J. T. & Takyar, S. S., Dec 1 2017, In: American journal of respiratory and critical care medicine. 196, 11, p. 1443-1455 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Myeloid STAT3 promotes lung tumorigenesis by transforming tumor immunosurveillance into tumor-promoting inflammation

Zhou, J., Qu, Z., Sun, F., Han, L., Li, L., Yan, S., Stabile, L. P., Chen, L. F., Siegfried, J. M. & Xiao, G., Mar 2017, In: Cancer Immunology Research. 5, 3, p. 257-268 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

58 Scopus citations

Phase 1/2 study of rilotumumab (AMG 102), a hepatocyte growth factor inhibitor, and erlotinib in patients with advanced non–small cell lung cancer

Tarhini, A. A., Rafique, I., Floros, T., Tran, P., Gooding, W. E., Villaruz, L. C., Burns, T. F., Friedland, D. M., Petro, D. P., Farooqui, M., Gomez-Garcia, J., Gaither-Davis, A., Dacic, S., Argiris, A., Socinski, M. A., Stabile, L. P. & Siegfried, J. M., Aug 1 2017, In: Cancer. 123, 15, p. 2936-2944 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

2016

A prospective and retrospective analysis of smoking behavior changes in ever smokers with high risk for lung cancer from New Mexico and Pennsylvania

Leng, S., Weissfeld, J. L., Picchi, M. A., Styn, M. A., Claus, E. D., Clark, V. P., Wu, G., Thomas, C. L., Gilliland, F. D., Yuan, J., Siegfried, J. M. & Belinsky, S. A., 2016, In: International Journal of Molecular Epidemiology and Genetics. 7, 2, p. 95-104 10 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

ATM protein is deficient in over 40% of lung adenocarcinomas

Villaruz, L. C., Jones, H., Dacic, S., Abberbock, S., Kurland, B. F., Stabile, L. P., Siegfried, J. M., Conrads, T. P., Smith, N. R., O'Connor, M. J., Pierce, A. J. & Bakkenist, C. J., 2016, In: Oncotarget. 7, 36, p. 57714-57725 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function

Sun, F., Qu, Z., Xiao, Y., Zhou, J., Burns, T. F., Stabile, L. P., Siegfried, J. M. & Xiao, G., May 5 2016, In: Oncogene. 35, 18, p. 2299-2310 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

2015

15q12 Variants, sputum gene promoter hypermethylation, and lung cancer risk: A GWAS in smokers

Leng, S., Liu, Y., Weissfeld, J. L., Thomas, C. L., Han, Y., Picchi, M. A., Edlund, C. K., Willink, R. P., Gaither Davis, A. L., Do, K. C., Nukui, T., Zhang, X., Burki, E. A., Van Den Berg, D., Romkes, M., Gauderman, W. J., Crowell, R. E., Tesfaigzi, Y., Stidley, C. A., Amos, C. I., & 3 othersSiegfried, J. M., Gilliland, F. D. & Belinsky, S. A., May 1 2015, In: Journal of the National Cancer Institute. 107, 5

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Epigenetic repression of CCDC37 and MAP1B links chronic obstructive pulmonary disease to lung cancer

Tessema, M., Yingling, C. M., Picchi, M. A., Wu, G., Liu, Y., Weissfeld, J. L., Siegfried, J. M., Tesfaigzi, Y. & Belinsky, S. A., Aug 1 2015, In: Journal of Thoracic Oncology. 10, 8, p. 1181-1188 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

39 Scopus citations

Expression of PAM50 Genes in Lung Cancer: Evidence that Interactions between Hormone Receptors and HER2/HER3 Contribute to Poor Outcome

Siegfried, J. M., Lin, Y., Diergaarde, B., Lin, H. M., Dacic, S., Pennathur, A., Weissfeld, J. L., Romkes, M., Nukui, T. & Stabile, L. P., 2015, In: Neoplasia (United States). 17, 11, p. 817-825 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma

Beumer, J. H., Fu, K. Y., Anyang, B. N., Siegfried, J. M. & Bakkenist, C. J., Oct 5 2015, In: BMC Cancer. 15, 1, 649.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Incidence of head and neck squamous cell carcinoma among subjects at high risk of lung cancer: Results from the Pittsburgh Lung Screening Study

Dixit, R., Weissfeld, J. L., Wilson, D. O., Balogh, P., Sufka, P., Siegfried, J. M., Grandis, J. R. & Diergaarde, B., May 1 2015, In: Cancer. 121, 9, p. 1431-1435 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Lung cancer risk prediction using common SNPs located in GWAS-identified susceptibility regions

Weissfeld, J. L., Lin, Y., Lin, H. M., Kurland, B. F., Wilson, D. O., Fuhrman, C. R., Pennathur, A., Romkes, M., Nukui, T., Yuan, J. M., Siegfried, J. M. & Diergaarde, B., Nov 1 2015, In: Journal of Thoracic Oncology. 10, 11, p. 1538-1545 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

2014

Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

Collisson, E. A., Campbell, J. D., Brooks, A. N., Berger, A. H., Lee, W., Chmielecki, J., Beer, D. G., Cope, L., Creighton, C. J., Danilova, L., Ding, L., Getz, G., Hammerman, P. S., Hayes, D. N., Hernandez, B., Herman, J. G., Heymach, J. V., Jurisica, I., Kucherlapati, R., Kwiatkowski, D., & 290 othersLadanyi, M., Robertson, G., Schultz, N., Shen, R., Sinha, R., Sougnez, C., Tsao, M. S., Travis, W. D., Weinstein, J. N., Wigle, D. A., Wilkerson, M. D., Chu, A., Cherniack, A. D., Hadjipanayis, A., Rosenberg, M., Weisenberger, D. J., Laird, P. W., Radenbaugh, A., Ma, S., Stuart, J. M., Byers, L. A., Baylin, S. B., Govindan, R., Meyerson, M., Gabriel, S. B., Cibulskis, K., Kim, J., Stewart, C., Lichtenstein, L., Lander, E. S., Lawrence, M. S., Getz, E., Fulton, R., Fulton, L. L., McLellan, M. D., Wilson, R. K., Ye, K., Fronick, C. C., Maher, C. A., Miller, C. A., Wendl, M. C., Cabanski, C., Mardis, E., Wheeler, D., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Chuah, E., Dhalla, N., Guin, R., Hirst, C., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Varhol, R., Robertson, A. G., Wye, N., Thiessen, N., Holt, R. A., Jones, S. J. M., Marra, M. A., Imielinski, M., Onofrio, R. C., Hodis, E., Zack, T., Helman, E., Pedamallu, C. S., Mesirov, J., Saksena, G., Schumacher, S. E., Carter, S. L., Garraway, L., Beroukhim, R., Lee, S., Mahadeshwar, H. S., Pantazi, A., Protopopov, A., Ren, X., Seth, S., Song, X., Tang, J., Yang, L., Zhang, J., Chen, P. C., Parfenov, M., Xu, A. W., Santoso, N., Chin, L., Park, P. J., Hoadley, K. A., Auman, J. T., Meng, S., Shi, Y., Buda, E., Waring, S., Veluvolu, U., Tan, D., Mieczkowski, P. A., Jones, C. D., Simons, J. V., Soloway, M. G., Bodenheimer, T., Jefferys, S. R., Roach, J., Hoyle, A. P., Wu, J., Balu, S., Singh, D., Prins, J. F., Marron, J. S., Parker, J. S., Perou, C. M., Liu, J., Maglinte, D. T., Lai, P. H., Bootwalla, M. S., Van Den Berg, D. J., Triche, T., Cho, J., DiCara, D., Heiman, D., Lin, P., Mallard, W., Voet, D., Zhang, H., Zou, L., Noble, M. S., Gehlenborg, N., Thorvaldsdottir, H., Nazaire, M. D., Robinson, J., Aksoy, B. A., Ciriello, G., Taylor, B. S., Dresdner, G., Gao, J., Gross, B., Seshan, V. E., Reva, B., Sumer, S. O., Weinhold, N., Sander, C., Ng, S., Zhu, J., Benz, C. C., Yau, C., Haussler, D., Spellman, P. T., Kimes, P. K., Broom, B. M., Wang, J., Lu, Y., Ng, P. K. S., Diao, L., Liu, W., Amos, C. I., Akbani, R., Mills, G. B., Curley, E., Paulauskis, J., Lau, K., Morris, S., Shelton, T., Mallery, D., Gardner, J., Penny, R., Saller, C., Tarvin, K., Richards, W. G., Cerfolio, R., Bryant, A., Raymond, D. P., Pennell, N. A., Farver, C., Czerwinski, C., Huelsenbeck-Dill, L., Iacocca, M., Petrelli, N., Rabeno, B., Brown, J., Bauer, T., Dolzhanskiy, C. O., Potapova, O., Rotin, D., Voronina, O., Nemirovich-Danchenko, E., Fedosenko, K. V., Gal, A., Behera, M., Ramalingam, S. S., Sica, G., Flieder, D., Boyd, J., Weaver, J. E., Kohl, B., Thinh, D. H. Q., Sandusky, G., Juhl, H., Duhig, E., Illei, P., Gabrielson, E., Shin, J., Lee, B., Rogers, K., Trusty, D., Brock, M. V., Williamson, C., Burks, E., Rieger-Christ, K., Holway, A., Sullivan, T., Asiedu, M. K., Kosari, F., Rekhtman, N., Zakowski, M., Rusch, V. W., Zippile, P., Suh, J., Pass, H., Goparaju, C., Owusu-Sarpong, Y., Bartlett, J. M. S., Kodeeswaran, S., Parfitt, J., Sekhon, H., Albert, M., Eckman, J., Myers, J. B., Morrison, C., Gaudioso, C., Borgia, J. A., Bonomi, P., Pool, M., Liptay, M. J., Moiseenko, F., Zaytseva, I., Dienemann, H., Meister, M., Schnabel, P. A., Muley, T. R., Peifer, M., Gomez-Fernandez, C., Herbert, L., Egea, S., Huang, M., Thorne, L. B., Boice, L., Salazar, A. H., Funkhouser, W. K., Rathmell, W. K., Dhir, R., Yousem, S. A., Dacic, S., Schneider, F., Siegfried, J. M., Hajek, R., Watson, M. A., McDonald, S., Meyers, B., Clarke, B., Yang, I. A., Fong, K. M., Hunter, L., Windsor, M., Bowman, R. V., Peters, S., Letovanec, I., Khan, K. Z., Jensen, M. A., Snyder, E. E., Srinivasan, D., Kahn, A. B., Baboud, J., Pot, D. A., Shaw, K. R. M., Sheth, M., Davidsen, T., Demchok, J. A., Yang, L., Wang, Z., Tarnuzzer, R., Zenklusen, J. C., Ozenberger, B. A., Sofia, H. J. & Cheney, R., 2014, In: Nature. 511, 7511, p. 543-550 8 p.

Research output: Contribution to journal › Article › peer-review

3972 Scopus citations

Co-targeting c-Met and COX-2 leads to enhanced inhibition of lung tumorigenesis in a murine model with heightened airway HGF

Stabile, L. P., Rothstein, M. E., Gubish, C. T., Cunningham, D. E., Lee, N. & Siegfried, J. M., Sep 2014, In: Journal of Thoracic Oncology. 9, 9, p. 1285-1293 9 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Dosing to rash: A phase II trial of the first-line erlotinib for patients with advanced non-small-cell lung cancer an Eastern Cooperative Oncology Group Study (E3503)

Brahmer, J. R., Lee, J. W., Traynor, A. M., Hidalgo, M. M., Kolesar, J. M., Siegfried, J. M., Guaglianone, P. P., Patel, J. D., Keppen, M. D. & Schiller, J. H., Jan 2014, In: European Journal of Cancer. 50, 2, p. 302-308 7 p.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Erlotinib, erlotinib-sulindac versus placebo: A randomized, double-blind, placebo-controlled window trial in operable head and neck cancer

Gross, N. D., Bauman, J. E., Gooding, W. E., Denq, W., Thomas, S. M., Wang, L., Chiosea, S., Hood, B. L., Flint, M. S., Sun, M., Conrads, T. P., Ferris, R. L., Johnson, J. T., Kim, S., Argiris, A., Wirth, L., Nikiforova, M. N., Siegfried, J. M. & Grandis, J. R., Jun 15 2014, In: Clinical Cancer Research. 20, 12, p. 3289-3298 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

44 Scopus citations

Estrongenic Steroid Hormones in Lung Cancer

Siegfried, J. M. & Stabile, L. P., Feb 2014, In: Seminars in Oncology. 41, 1, p. 5-16 12 p.

Research output: Contribution to journal › Article › peer-review

93 Scopus citations

Increased methylation of lung cancer-associated genes in sputum DNA of former smokers with chronic mucous hypersecretion

Bruse, S., Petersen, H., Weissfeld, J., Picchi, M., Willink, R., Do, K., Siegfried, J., Belinsky, S. A. & Tesfaigzi, Y., Jan 9 2014, In: Respiratory research. 15, 1, 2.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Inherited variation in the ATP-binding cassette transporter ABCB1 and survival after chemotherapy for stage III-IV lung cancer

Weissfeld, J. L., Diergaarde, B., Nukui, T., Buch, S., Pennathur, A., Socinski, M. A., Siegfried, J. M. & Romkes, M., Sep 2014, In: Journal of Thoracic Oncology. 9, 9, p. 1264-1271 8 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Matrix metalloproteinase-19 promotes metastatic behavior in vitro and is associated with increased mortality in non-small cell lung cancer

Yu, G., Herazo-Maya, J. D., Nukui, T., Romkes, M., Parwani, A., Juan-Guardela, B. M., Robertson, J., Gauldie, J., Siegfried, J. M., Kaminski, N. & Kass, D. J., Oct 1 2014, In: American journal of respiratory and critical care medicine. 190, 7, p. 780-790 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

49 Scopus citations

Pan-erbB inhibition potentiates BRAF inhibitors for melanoma treatment

Ng, Y. K., Lee, J. Y., Supko, K. M., Khan, A., Torres, S. M., Berwick, M., Ho, J., Kirkwood, J. M., Siegfried, J. M. & Stabile, L. P., Jun 2014, In: Melanoma research. 24, 3, p. 207-218 12 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

RET rearrangements in lung adenocarcinoma and radiation

Dacic, S., Luvison, A., Evdokimova, V., Kelly, L., Siegfried, J. M., Villaruz, L. C., Socinski, M. A. & Nikiforov, Y. E., Jan 2014, In: Journal of Thoracic Oncology. 9, 1, p. 118-120 3 p.

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Smoking out reproductive hormone actions in lung cancer

Siegfried, J. M., Jan 2014, In: Molecular Cancer Research. 12, 1, p. 24-31 8 p.

Research output: Contribution to journal › Review article › peer-review

30 Scopus citations

Validation of a blood protein signature for non-small cell lung cancer

Mehan, M. R., Williams, S. A., Siegfried, J. M., Bigbee, W. L., Weissfeld, J. L., Wilson, D. O., Pass, H. I., Rom, W. N., Muley, T., Meister, M., Franklin, W., Miller, Y. E., Brody, E. N. & Ostroff, R. M., Aug 1 2014, In: Clinical Proteomics. 11, 1, 32.

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

2013

Computerized identification of airway wall in CT examinations using a 3D active surface evolution approach

Gu, S., Fuhrman, C., Meng, X., Siegfried, J. M., Gur, D., Leader, J. K., Sciurba, F. C. & Pu, J., Apr 2013, In: Medical Image Analysis. 17, 3, p. 283-296 14 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Correction: c-Src activation mediates erlotinib resistance in head and neck cancer by stimulating c-Met (Clinical Cancer Research (2013) 19, (380-392))

Stabile, L. P., He, G., Lui, V. W., Thomas, S., Henry, C., Gubish, C. T., Joyce, S., Quesnelle, K. M., Siegfried, J. M. & Grandis, Jul 1 2013, In: Clinical Cancer Research. 19, 13, p. 3715 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

C-Src activation mediates erlotinib resistance in head and neck cancer by stimulating c-Met

Stabile, L. P., He, G., Lui, V. W. Y., Henry, C., Gubish, C. T., Joyce, S., Quesnelle, K. M., Siegfried, J. M. & Grandis, J. R., Jan 15 2013, In: Clinical Cancer Research. 19, 2, p. 380-392 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

86 Scopus citations

Elevated gastrin-releasing peptide receptor mRNA expression in buccal mucosa: Association with head and neck squamous cell carcinoma

Egloff, A. M., Liu, X., Davis, A. L. G., Trevelline, B. K., Vuga, M., Siegfried, J. M. & Grandis, J. R., Feb 2013, In: Head and Neck. 35, 2, p. 270-279 10 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Genetic variation in ESR2 and estrogen receptor-beta expression in lung tumors

Song, J. Y., Siegfried, J. M., Diergaarde, B., Land, S. R., Bowser, R., Stabile, L. P., Dacic, S., Dhir, R., Nukui, T., Romkes, M. & Weissfeld, J. L., Aug 2013, In: Cancer Epidemiology. 37, 4, p. 518-522 5 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Optimal threshold in CT quantification of emphysema

Wang, Z., Gu, S., Leader, J. K., Kundu, S., Tedrow, J. R., Sciurba, F. C., Gur, D., Siegfried, J. M. & Pu, J., Apr 2013, In: European Radiology. 23, 4, p. 975-984 10 p.

Research output: Contribution to journal › Article › peer-review

106 Scopus citations

Phase I trial of carboplatin and etoposide in combination with panobinostat in patients with lung cancer

Tarhini, A. A., Zahoor, H., Mclaughlin, B., Gooding, W. E., Schmitz, J. C., Siegfried, J. M., Socinski, M. A. & Argiris, A., Oct 2013, In: Anticancer Research. 33, 10, p. 4475-4482 8 p.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

The prognostic and predictive value of KRAS oncogene substitutions in lung adenocarcinoma

Villaruz, L. C., Socinski, M. A., Cunningham, D. E., Chiosea, S. I., Burns, T. F., Siegfried, J. M. & Dacic, S., Jun 15 2013, In: Cancer. 119, 12, p. 2268-2274 7 p.

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

2012

A multiplexed serum biomarker immunoassay panel discriminates clinical lung cancer patients from high-risk individuals found to be cancer-free by CT screening

Bigbee, W. L., Gopalakrishnan, V., Weissfeld, J. L., Wilson, D. O., Dacic, S., Lokshin, A. E. & Siegfried, J. M., Apr 2012, In: Journal of Thoracic Oncology. 7, 4, p. 698-708 11 p.

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

Anatomic segmentectomy for the solitary pulmonary nodule and early-stage lung cancer

Schuchert, M. J., Abbas, G., Awais, O., Pennathur, A., Nason, K. S., Wilson, D. O., Siegfried, J. M., Luketich, J. D. & Landreneau, R. J., Jun 1 2012, In: Annals of Thoracic Surgery. 93, 6, p. 1780-1787 8 p.

Research output: Contribution to journal › Article › peer-review

103 Scopus citations

Automated lobe-based airway labeling

Gu, S., Wang, Z., Siegfried, J. M., Wilson, D., Bigbee, W. L. & Pu, J., 2012, In: International Journal of Biomedical Imaging. 2012, 382806.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Combining the multitargeted tyrosine kinase inhibitor vandetanib with the antiestrogen fulvestrant enhances its antitumor effect in non-small cell lung cancer

Siegfried, J. M., Gubish, C. T., Rothstein, M. E., Henry, C. & Stabile, L. P., Mar 2012, In: Journal of Thoracic Oncology. 7, 3, p. 485-495 11 p.

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Comprehensive genomic characterization of squamous cell lung cancers

Hammerman, P. S., Voet, D., Lawrence, M. S., Voet, D., Jing, R., Cibulskis, K., Sivachenko, A., Stojanov, P., McKenna, A., Lander, E. S., Gabriel, S., Getz, G., Imielinski, M., Helman, E., Hernandez, B., Pho, N. H., Meyerson, M., Chu, A., Hye-Chun, J. E., Mungall, A. J., & 320 othersPleasance, E., Robertson, A. G., Sipahimalani, P., Stoll, D., Balasundaram, M., Birol, I., Butterfield, Y. S. N., Chuah, E., Coope, R. J. N., Corbett, R., Dhalla, N., Guin, R., He, A., Hirst, C., Hirst, M., Holt, R. A., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, K., Nip, K. M., Olshen, A., Schein, J. E., Slobodan, J. R., Tam, A., Thiessen, N., Varhol, R., Zeng, T., Zhao, Y., Jones, S. J. M., Marra, M. A., Saksena, G., Cherniack, A. D., Schumacher, S. E., Tabak, B., Carter, S. L., Nguyen, H., Onofrio, R. C., Crenshaw, A., Ardlie, K., Beroukhim, R., Winckler, W., Protopopov, A., Zhang, J., Hadjipanayis, A., Lee, S., Xi, R., Yang, L., Ren, X., Zhang, H., Shukla, S., Chen, P. C., Haseley, P., Lee, E., Chin, L., Park, P. J., Kucherlapati, R., Socci, N. D., Liang, Y., Schultz, N., Borsu, L., Lash, A. E., Viale, A., Sander, C., Ladanyi, M., Auman, J. T., Hoadley, K. A., Wilkerson, M. D., Shi, Y., Liquori, C., Meng, S., Li, L., Turman, Y. J., Topal, M. D., Tan, D., Waring, S., Buda, E., Walsh, J., Jones, C. D., Mieczkowski, P. A., Singh, D., Wu, J., Gulabani, A., Dolina, P., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Stuart, J., Mose, L. E., Jefferys, S. R., Balu, S., O'Connor, B. D., Chiang, D., Liu, J., Chiang, D. Y., Hayes, D. N., Perou, C. M., Cope, L., Weisenberger, D., Danilova, L., Weisenberger, D. J., Maglinte, D. T., Pan, F., Van Den Berg, D. J., Triche, T., Herman, J. G., Baylin, S. B., Laird, P. W., Noble, M., Gehlenborg, N., DiCara, D., Zhang, J., Wu, C. J., Liu, S. Y., Zou, L., Lin, P., Cho, J., Nazaire, M. D., Robinson, J., Thorvaldsdottir, H., Mesirov, J., Sinha, R., Ciriello, G., Cerami, E., Gross, B., Jacobsen, A., Gao, J., Aksoy, B. A., Weinhold, N., Ramirez, R., Taylor, B. S., Antipin, Y., Reva, B., Mo, Q., Seshan, V., Paik, P. K., Akbani, R., Zhang, N., Broom, B. M., Casasent, T., Unruh, A., Wakefield, C., Cason, R. C., Baggerly, K. A., Weinstein, J. N., Haussler, D., Benz, C. C., Stuart, J. M., Zhu, J., Szeto, C., Scott, G. K., Yau, C., Ng, S., Goldstein, T., Waltman, P., Sokolov, A., Collisson, E., Ellrott, K., Collisson, E. A., Zerbino, D., Ma, S., Craft, B., Du, Y., Cabanski, C., Walter, V., Marron, J. S., Liu, Y., Wang, K., Prins, J. F., Creighton, C. J., Zhang, Y., Travis, W. D., Rekhtman, N., Yi, J., Aubry, M. C., Cheney, R., Dacic, S., Flieder, D., Funkhouser, W., Illei, P., Myers, J., Tsao, M. S., Penny, R., Mallery, D., Shelton, T., Hatfield, M., Morris, S., Yena, P., Shelton, C., Sherman, M., Paulauskis, J., Govindan, R., Azodo, I., Beer, D., Bose, R., Byers, L. A., Carbone, D., Chang, L. W., Chun, E., Ding, L., Heymach, J., Ida, C., Johnson, B., Jurisica, I., Kaufman, J., Kosari, F., Kwiatkowski, D., Maher, C. A., Mungall, A., Pao, W., Peifer, M., Robertson, G., Rusch, V., Siegfried, J., Sougnez, C., Thomas, R. K., Tomaszek, S., Vaske, C., Wheeler, D., Wigle, D. A., Wilks, C., Zhang, J. J., Jensen, M. A., Sfeir, R., Kahn, A. B., Chu, A. L., Kothiyal, P., Wang, Z., Snyder, E. E., Pontius, J., Pihl, T. D., Ayala, B., Backus, M., Walton, J., Baboud, J., Berton, D. L., Nicholls, M. C., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P. A., Alonso, S., Sanbhadti, R. N., Barletta, S. P., Greene, J. M., Pot, D. A., Bandarchi-Chamkhaleh, B., Boyd, J., Weaver, J., Azodo, I. A., Tomaszek, S. C., Aubry, M. C., Ida, C. M., Yang, P., Brock, M. V., Rogers, K., Rutledge, M., Brown, T., Lee, B., Shin, J., Trusty, D., Dhir, R., Siegfried, J. M., Potapova, O., Fedosenko, K. V., Nemirovich-Danchenko, E., Zakowski, M., Iacocca, M. V., Brown, J., Rabeno, B., Czerwinski, C., Petrelli, N., Fan, Z., Todaro, N., Eckman, J., Rathmell, W. K., Thorne, L. B., Huang, M., Boice, L., Hill, A., Curley, E., Morrison, C., Gaudioso, C., Bartlett, J. M. S., Kodeeswaran, S., Zanke, B., Sekhon, H., David, K., Juhl, H., Le, X. V., Kohl, B., Thorp, R., Tien, N. V., Bang, N. V., Sussman, H., Phu, B. D., Hajek, R., Hung, N. P., Khan, K. Z., Muley, T., Mills Shaw, K. R., Sheth, M., Yang, L., Buetow, K., Davidsen, T., Demchok, J. A., Eley, G., Ferguson, M., Dillon, L. A. L., Schaefer, C., Guyer, M. S., Ozenberger, B. A., Palchik, J. D., Peterson, J., Sofia, H. J., Thomson, E., Johnson, B. E. & Shen, R., Sep 27 2012, In: Nature. 489, 7417, p. 519-525 7 p.

Research output: Contribution to journal › Article › peer-review

3122 Scopus citations

Jill M Siegfried

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