Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Elucidating the biophysics of pre-fibrillar, toxic tau oligomers: from amino acid motifs to neuronal dysfunction
Sachs, J. N., Ashe, K. H., Nelson, K. & Yuan, S.
NIH NAT'L INSTITUTE ON AGING (NIA)
9/30/21 → 5/31/24
Project: Research project
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Understanding the structural dynamics of TNF receptors
NIH NIGMS NATL INST OF GENERAL
6/1/19 → 3/31/24
Project: Research project
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Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein
Braun, A. R., Kochen, N. N., Yuen, S. L., Liao, E. E., Cornea, R. L., Thomas, D. D. & Sachs, J. N., Jan 1 2023, In: ASN Neuro. 15Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery of a Non-competitive TNFR1 Antagonist Affibody with Picomolar Monovalent Potency That Does Not Affect TNFR2 Function
Vunnam, N., Been, M. J., Huber, E., Paulson, C., Szymonski, S., Hackel, B. J. & Sachs, J. N., Apr 3 2023, In: Molecular pharmaceutics. 20, 4, p. 1884-1897 14 p.Research output: Contribution to journal › Article › peer-review
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Indirubin Inhibits TRAIL-Induced Activation of Death Receptor 5 in Jurkat Cells
Young, M. C., Vunnam, N., Rebbeck, R. T., Yuen, S. L., Thomas, D. D. & Sachs, J. N., Jan 2023, In: Natural Product Communications. 18, 1Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †
Vunnam, N., Young, M. C., Liao, E. E., Lo, C. H., Huber, E., Been, M. J., Thomas, D. D. & Sachs, J. N., 2023, In: Cancer Biology and Therapy. 24, 1, 2176692.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
pH Effects Can Dominate Chemical Shift Perturbations in 1H,15N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions
Pandey, A. K., Buchholz, C. R., Nathan Kochen, N., Pomerantz, W. C. K., Braun, A. R. & Sachs, J. N., Feb 15 2023, In: ACS Chemical Neuroscience. 14, 4, p. 800-808 9 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations