Photo of Kathleen Boris-Lawrie

Kathleen Boris-Lawrie

Professor and Chair

Accepting PhD Students

PhD projects

RNA viruses that cause cancer and AIDS

Willing to speak to media

1987 …2020

Research activity per year

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Personal profile

Research interests

D. Boris-Lawrie has extensive expertise in the fields of retrovirology and gene expression and training graduate students that are successful in the biomedical workforce. She has had the opportunity to lead (PI) or collaborate (co-I) on NIH funded grants (R01, P50, P01) and establish a track record in team building, which has resulted in several publications in peer-reviewed journals. Her research is focused on unraveling genetic, biochemical and biophysical interactions of ribonucleoprotein complexes using viral models to understand progression to cancer and productive infections. In ground-breaking work, Dr. Boris-Lawrie and her lab group discovered and characterized of the necessary role of RNA helicase A/DHX9 in the translation of selected viral and host mRNAs, which has led to the realization nuclear RNA-binding proteins regulate protein synthesis in the cytoplasm. These studies also led to the discovery of the functional and structural conservation of the DHX9-responsive element across the Retroviridae and in RNAs expressed by animals and humans. Dr. Boris-Lawrie's mechanistic studies are exposing non-coding RNA-based therapeutic target to control disorders caused by viruses and transformed cells. 

 

Research interests

Retroviruses, Oncogenic viruses, Viral vectors, RNA structural biology, RNA-protein interactions

Professional Information

Fellow, American Academy of Microbiology

Fellow, AAAS

 

Expertise related to UN SDGs

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 12 - Responsible Consumption and Production

External Positions

NIH Recombinant DNA Advisory Committee, NIH

Aug 1 2016Jul 31 2020

Research interests

  • Virology
  • Molecular Biology
  • Cancer
  • RNA Structural Biology

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