Mahsa Abassi

2023

5-Flucytosine Longitudinal Antifungal Susceptibility Testing of Cryptococcus neoformans: A Substudy of the EnACT Trial Testing Oral Amphotericin

ENACT Trial Team, Dec 1 2023, In: Open Forum Infectious Diseases. 10, 12, ofad596.

Research output: Contribution to journal › Article › peer-review

Open Access

Cryptococcal meningitis

Tugume, L., Ssebambulidde, K., Kasibante, J., Ellis, J., Wake, R. M., Gakuru, J., Lawrence, D. S., Abassi, M., Rajasingham, R., Meya, D. B. & Boulware, D. R., Dec 2023, In: Nature Reviews Disease Primers. 9, 1, 62.

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Diagnosis and management of cryptococcal meningitis in HIV-infected adults

McHale, T. C., Boulware, D. R., Kasibante, J., Ssebambulidde, K., Skipper, C. P. & Abassi, M., 2023, In: Clinical microbiology reviews. 36, 4

Research output: Contribution to journal › Review article › peer-review

Oral Lipid Nanocrystal Amphotericin B for Cryptococcal Meningitis: A Randomized Clinical Trial

Boulware, D. R., Atukunda, M., Kagimu, E., Musubire, A. K., Akampurira, A., Tugume, L., Ssebambulidde, K., Kasibante, J., Nsangi, L., Mugabi, T., Gakuru, J., Kimuda, S., Kasozi, D., Namombwe, S., Turyasingura, I., Rutakingirwa, M. K., Mpoza, E., Kigozi, E., Muzoora, C., Ellis, J., & 9 othersSkipper, C. P., Matkovits, T., Williamson, P. R., Williams, D. A., Fieberg, A., Huppler Hullsiek, K., Abassi, M., Dai, B. & Meya, D. B., Dec 15 2023, In: Clinical Infectious Diseases. 77, 12, p. 1659-1667 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Outpatient Cryptococcal Antigen Screening Is Associated With Favorable Baseline Characteristics and Improved Survival in Persons With Cryptococcal Meningitis in Uganda

Levin, A. E., Bangdiwala, A. S., Nalintya, E., Kagimu, E., Kasibante, J., Rutakingirwa, M. K., Mpoza, E., Jjunju, S., Nuwagira, E., Naluyima, R., Kirumira, P., Hou, C., Ssebambulidde, K., Musubire, A. K., Williams, D. A., Abassi, M., Muzoora, C., Huppler Hullsiek, K., Rajasingham, R., Meya, D. B., & 2 othersBoulware, D. R. & Skipper, C. P., Feb 1 2023, In: Clinical Infectious Diseases. 76, 3, p. E759-E765

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Recurrence of Symptoms following Cryptococcal Meningitis: Characterizing a Diagnostic Conundrum with Multiple Etiologies

Bahr, N. C., Skipper, C. P., Huppler-Hullsiek, K., Ssebambulidde, K., Morawski, B. M., Engen, N. W., Nuwagira, E., Quinn, C. M., Ramachandran, P. S., Evans, E. E., Lofgren, S. M., Abassi, M., Muzoora, C., Wilson, M. R., Meya, D. B., Rhein, J. & Boulware, D. R., Mar 15 2023, In: Clinical Infectious Diseases. 76, 6, p. 1080-1087 8 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Sterile Cerebrospinal Fluid Culture at Cryptococcal Meningitis Diagnosis Is Associated with High Mortality

Skipper, C. P., Huppler Hullsiek, K., Stadelman, A., Williams, D. A., Ssebambulidde, K., Okafor, E., Tugume, L., Nuwagira, E., Akampurira, A., Musubire, A. K., Abassi, M., Muzoora, C., Rhein, J., Boulware, D. R. & Meya, D. B., Jan 2023, In: Journal of Fungi. 9, 1, 46.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

2022

Fluvoxamine for the treatment of COVID-19

Boulware, D. R. & Abassi, M., Mar 2022, In: The Lancet Global Health. 10, 3, p. e329

Research output: Contribution to journal › Letter › peer-review

Open Access

4 Scopus citations

Therapeutic Lumbar Punctures in Human Immunodeficiency Virus-Associated Cryptococcal Meningitis: Should Opening Pressure Direct Management?

Kagimu, E., Engen, N., Ssebambulidde, K., Kasibante, J., Kiiza, T. K., Mpoza, E., Tugume, L., Nuwagira, E., Nsangi, L., Williams, D. A., Hullsiek, K. H., Boulware, D. R., Meya, D. B., Rhein, J., Abassi, M. & Musubire, A. K., Sep 2022, In: Open Forum Infectious Diseases. 9, 9, ofac416.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

2021

Cerebrospinal Fluid Lactate as a Prognostic Marker of Disease Severity and Mortality in Cryptococcal Meningitis

Abassi, M., Bangdiwala, A. S., Nuwagira, E., Kandole Tadeo, K., Okirwoth, M., Williams, D. A., Mpoza, E., Tugume, L., Ssebambulidde, K., Huppler Hullsiek, K., Musubire, A. K., Muzoora, C., Rhein, J., Meya, D. B. & Boulware, D. R., Nov 1 2021, In: Clinical Infectious Diseases. 73, 9, p. E3077-E3082

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Hydroxychloroquine as Pre-exposure Prophylaxis for Coronavirus Disease 2019 (COVID-19) in Healthcare Workers: A Randomized Trial

COVID PREP team, Jun 1 2021, In: Clinical Infectious Diseases. 72, 11, p. E835-E843

Research output: Contribution to journal › Article › peer-review

Open Access

75 Scopus citations

Lessons Learned from Conducting Internet-Based Randomized Clinical Trials during a Global Pandemic

Pullen, M. F., Pastick, K. A., Williams, D. A., Nascene, A. A., Bangdiwala, A. S., Okafor, E. C., Hullsiek, K. H., Skipper, C. P., Lofgren, S. M., Engen, N., Abassi, M., Mcdonald, E. G., Lee, T. C., Rajasingham, R. & Boulware, D. R., 2021, In: Open Forum Infectious Diseases. 8, 2, ofaa602.

Research output: Contribution to journal › Review article › peer-review

Open Access

5 Scopus citations

2020

A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19

Boulware, D. R., Pullen, M. F., Bangdiwala, A. S., Pastick, K., Lofgren, S. M., Okafor, E., Skipper, C. P., Nascene, A., Nicol, M. R., Abassi, M., Wyman Engen, N., Cheng, M. P., Lother, S. A., MacKenzie, L. J., Drobot, G., Marten, N., Zarychanski, R., Kelly, L. E., Schwartz, I. S., McDonald, E. G., & 3 othersRajasingham, R., Lee, T. C. & Huppler Hullsiek, K., Jun 3 2020, In: New England Journal of Medicine.

Research output: Contribution to journal › Article › peer-review

Open Access

966 Scopus citations

Baseline Serum C-Reactive Protein Level Predicts Mortality in Cryptococcal Meningitis

Chesdachai, S., Engen, N. W., Rhein, J., Tugume, L., Kiiza Kandole, T., Abassi, M., Ssebambulidde, K., Kasibante, J., Williams, D. A., Skipper, C. P., Hullsiek, K. H., Musubire, A. K., Rajasingham, R., Meya, D. B. & Boulware, D. R., Dec 1 2020, In: Open Forum Infectious Diseases. 7, 12, ofaa530.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Cerebrospinal fluid early fungicidal activity as a surrogate endpoint for cryptococcal meningitis survival in clinical trials

ASTRO-CM Team, Oct 1 2020, In: Clinical Infectious Diseases. 71, 7, p. E45-E49

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19: A Randomized Trial

Skipper, C. P., Pastick, K. A., Engen, N. S., Bangdiwala, A. S., Abassi, M., Lofgren, S. M., Williams, D. A., Okafor, E. C., Pullen, M. F., Nicol, M. R., Nascene, A. A., Huppler Hullsiek, K., Cheng, M. P., Luke, D., Lother, S. A., MacKenzie, L. J., Drobot, G., Kelly, L. E., Schwartz, I. S., Zarychanski, R., & 4 othersMcDonald, E. G., Lee, T. C., Rajasingham, R. & Boulware, D. R., Oct 20 2020, In: Annals of Internal Medicine. 173, 8, p. 623-631 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

380 Scopus citations

Phase I EnACT trial of the safety and tolerability of a novel oral formulation of amphotericin B

Skipper, C. P., Atukunda, M., Stadelman, A., Engen, N. W., Bangdiwala, A. S., Hullsiek, K. H., Abassi, M., Rhein, J., Nicol, M. R., Laker, E., Williams, D. A., Mannino, R., Matkovits, T., Meya, D. B. & Boulware, D. R., Oct 2020, In: Antimicrobial agents and chemotherapy. 64, 10, e00838.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Post-exposure prophylaxis or pre-emptive therapy for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): study protocol for a pragmatic randomized-controlled trial

Lother, S. A., Abassi, M., Agostinis, A., Bangdiwala, A. S., Cheng, M. P., Drobot, G., Engen, N., Hullsiek, K. H., Kelly, L. E., Lee, T. C., Lofgren, S. M., MacKenzie, L. J., Marten, N., McDonald, E. G., Okafor, E. C., Pastick, K. A., Pullen, M. F., Rajasingham, R., Schwartz, I., Skipper, C. P., & 3 othersTurgeon, A. F., Zarychanski, R. & Boulware, D. R., Sep 1 2020, In: Canadian Journal of Anesthesia. 67, 9, p. 1201-1211 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Review: Hydroxychloroquine and chloroquine for treatment of SARS-CoV-2 (COVID-19)

Pastick, K. A., Okafor, E. C., Wang, F., Lofgren, S. M., Skipper, C. P., Nicol, M. R., Pullen, M. F., Rajasingham, R., McDonald, E. G., Lee, T. C., Schwartz, I. S., Kelly, L. E., Lother, S. A., Mitjà, O., Letang, E., Abassi, M. & Boulware, D. R., Mar 16 2020, In: Open Forum Infectious Diseases. 7, 4, ofaa130.

Research output: Contribution to journal › Review article › peer-review

Open Access

148 Scopus citations

Safety of Hydroxychloroquine among Outpatient Clinical Trial Participants for COVID-19

Lofgren, S. M., Nicol, M. R., Bangdiwala, A. S., Pastick, K. A., Okafor, E. C., Skipper, C. P., Pullen, M. F., Engen, N. W., Abassi, M., Williams, D. A., Nascene, A. A., Axelrod, M. L., Lother, S. A., MacKenzie, L. J., Drobot, G., Marten, N., Cheng, M. P., Zarychanski, R., Schwartz, I. S., Silverman, M., & 7 othersChagla, Z., Kelly, L. E., McDonald, E. G., Lee, T. C., Hullsiek, K. H., Boulware, D. R. & Rajasingham, R., Nov 1 2020, In: Open Forum Infectious Diseases. 7, 11, ofaa500.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Symptoms of COVID-19 outpatients in the United States

Pullen, M. F., Skipper, C. P., Huppler Hullsiek, K., Bangdiwala, A. S., Pastick, K. A., Okafor, E. C., Lofgren, S. M., Rajasingham, R., Engen, N. S., Galdys, A. L., Williams, D. A., Abassi, M. & Boulware, D. R., Jul 1 2020, In: Open Forum Infectious Diseases. 7, 7, ofaa271.

Research output: Contribution to journal › Article › peer-review

Open Access

42 Scopus citations

2019

Adjunctive sertraline for HIV-associated cryptococcal meningitis: a randomised, placebo-controlled, double-blind phase 3 trial

ASTRO-CM Team, Rhein, J., Huppler Hullsiek, K., Pastick, K. A., Williams, D. A., Bangdiwala, A. S., Abassi, M., Nicol, M. R., Meya, D. B. & Boulware, D. R., Aug 2019, In: The Lancet Infectious Diseases. 19, 8, p. 843-851 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

82 Scopus citations

Diagnosis and management of central nervous system cryptococcal infections in HIV-infected adults

Skipper, C., Abassi, M. & Boulware, D. R., Sep 2019, In: Journal of Fungi. 5, 3, 65.

Research output: Contribution to journal › Review article › peer-review

Open Access

21 Scopus citations

HIV-Associated cryptococcal meningitis occurring at relatively higher CD4 counts

Tugume, L., Rhein, J., Hullsiek, K. H., Mpoza, E., Kiggundu, R., Ssebambulidde, K., Schutz, C., Taseera, K., Williams, D. A., Abassi, M., Muzoora, C., Musubire, A. K., Meintjes, G., Meya, D. B., Boulware, D. R., Nabeta, H. W., Ndyetukira, J. F., Ahimbisibwe, C., Kugonza, F., Namuju, C., & 28 othersSadiq, A., Namudde, A., Mwesigye, J., Kandole, T. K., Kwizera, R., Kirumira, P., Okirwoth, M., Akampurira, A., Luggya, T., Kaboggoza, J., Laker, E., Atwine, L., Muganzi, D., Evans, E. E., Bridge, S. C., Velamakanni, S. S., Rajasingham, R., Pastick, K., Stadelman, A., Flynn, A., Fujita, A. W., Mukaremera, L., Lofgren, S. M., Morawski, B. M., Bangdiwala, A., Nielsen, K., Bohjanen, P. R. & Kambugu, A., Feb 23 2019, In: Journal of Infectious Diseases. 219, 6, p. 877-883 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

Letter to the Editor

Abassi, M. & Sacktor, N., Dec 1 2019, In: Journal of neurovirology. 25, 6, p. 897-898 2 p.

Research output: Contribution to journal › Letter › peer-review

Minimum Inhibitory Concentration Distribution of Fluconazole Against Cryptococcus Species and the Fluconazole Exposure Prediction Model

Chesdachai, S., Rajasingham, R., Nicol, M. R., Meya, D. B., Bongomin, F., Abassi, M., Skipper, C., Kwizera, R., Rhein, J. & Boulware, D. R., Sep 30 2019, In: Open Forum Infectious Diseases. 6, 10, ofz369.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Pharmacokinetics-pharmacodynamics of sertraline as an antifungal in HIV-infected Ugandans with cryptococcal meningitis

ASTRO-CM Study Team, Dec 1 2019, In: Journal of Pharmacokinetics and Pharmacodynamics. 46, 6, p. 565-576 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Seizures in Human Immunodeficiency Virus-Associated Cryptococcal Meningitis: Predictors and Outcomes

Pastick, K., Bangdiwala, A. S., Abassi, M., Flynn, A. G., Morawski, B. M., Musubire, A. K., Eneh, P. C., Schutz, C., Taseera, K., Rhein, J., Huppler Hullsiek, K., Nicol, M. R., Vidal, J. E., Nakasujja, N., Meintjes, G., Muzoora, C., Meya, D. B. & Boulware, D. R., Nov 1 2019, In: Open Forum Infectious Diseases. 6, 11, OFZ478.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Symptomatic Cryptococcal Antigenemia Presenting as Early Cryptococcal Meningitis with Negative Cerebral Spinal Fluid Analysis

For the Adjunctive Sertraline for Treatment of HIV-associated Cryptococcal Meningitis Team, Jun 2019, In: Clinical Infectious Diseases. 68, 12, p. 2094-2098 5 p., ciy817.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

The conundrum of clinical trials and standard of care in sub-Saharan Africa – the research nurse perspective

Frances Ndyetukira, J., Kwizera, R., Kugonza, F., Ahimbisibwe, C., Namujju, C., Sadiq, A., Namudde, A., Williams, D., Abassi, M., Rhein, J., Boulware, D. R. & Meya, D. B., Dec 1 2019, In: Journal of Research in Nursing. 24, 8, p. 649-660 12 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2018

Cerebral oximetry for detecting high-mortality risk patients with cryptococcal meningitis

ASTRO-CM Trial Team, Jun 1 2018, In: Open Forum Infectious Diseases. 5, 6

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Cryptococcal Disease in the Era of "test and Treat": Is There Cause for Concern?

Abassi, M., Rhein, J., Meya, D. B. & Boulware, D. R., Jan 1 2018, In: Open Forum Infectious Diseases. 5, 1, ofx274.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Detrimental outcomes of unmasking cryptococcal meningitis with recent ARt initiation

ASTRO-CM Study Team, Aug 1 2018, In: Open Forum Infectious Diseases. 5, 8

Research output: Contribution to journal › Article › peer-review

Open Access

46 Scopus citations

Emerging fluconazole resistance: Implications for the management of cryptococcal meningitis

Mpoza, E., Rhein, J. & Abassi, M., Mar 2018, In: Medical Mycology Case Reports. 19, p. 30-32 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

30 Scopus citations

Evaluation of a point-of-care immunoassay test kit ‘StrongStep’ for cryptococcal antigen detection

Mpoza, E., Mukaremera, L., Kundura, D. A., Akampurira, A., Luggya, T., Tadeo, K. K., Pastick, K. A., Bridge, S. C., Tugume, L., Kiggundu, R., Musubire, A. K., Williams, D. A., Muzoora, C., Nalintya, E., Rajasingham, R., Rhein, J., Boulware, D. R., Meya, D. B. & Abassi, M., Jan 2018, In: PloS one. 13, 1, e0190652.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

2017

Cerebrospinal fluid biomarkers and HIV-associated neurocognitive disorders in HIV-infected individuals in Rakai, Uganda

Abassi, M., Morawski, B. M., Nakigozi, G., Nakasujja, N., Kong, X., Meya, D. B., Robertson, K., Gray, R., Wawer, M. J., Sacktor, N. & Boulware, D. R., Jun 1 2017, In: Journal of neurovirology. 23, 3, p. 369-375 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

48 Scopus citations

Differences in immunologic factors among patients presenting with altered mental status during cryptococcal meningitis

Lofgren, S., Hullsiek, K. H., Morawski, B. M., Nabeta, H. W., Kiggundu, R., Taseera, K., Musubire, A., Schutz, C., Abassi, M., Bahr, N. C., Tugume, L., Muzoora, C., Williams, D. A., Rolfes, M. A., Velamakanni, S. S., Rajasingham, R., Meintjes, G., Rhein, J., Meya, D. B. & Boulware, D. R., Mar 1 2017, In: Journal of Infectious Diseases. 215, 5, p. 693-697 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Prognostic implications of baseline anaemia and changes in haemoglobin concentrations with amphotericin B therapy for cryptococcal meningitis

Tugume, L., Morawski, B., Abassi, M., Bahr, N., Kiggundu, R., Nabeta, H., Hullsiek, K., Taseera, K., Musubire, A., Schutz, C., Muzoora, C., Williams, D., Rolfes, M., Meintjes, G., Rhein, J., Meya, D. & Boulware, D., Jan 1 2017, In: HIV Medicine. 18, 1, p. 13-20 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Recent advances in AIDS-related cryptococcal meningitis treatment with an emphasis on resource limited settings

Lofgren, S., Abassi, M., Rhein, J. & Boulware, D. R., Apr 3 2017, In: Expert review of anti-infective therapy. 15, 4, p. 331-340 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

13 Scopus citations

2016

Effects of Tenofovir and Amphotericin B Deoxycholate Coadministration on Kidney Function in Patients Treated for Cryptococcal Meningitis

ASTRO-CM Team & Boulware, D. R., Jan 1 2016, In: Journal of Acquired Immune Deficiency Syndromes. 71, 1, p. 65-69 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Efficacy of adjunctive sertraline for the treatment of HIV-associated cryptococcal meningitis: An open-label dose-ranging study

Rhein, J., Morawski, B. M., Hullsiek, K. H., Nabeta, H. W., Kiggundu, R., Tugume, L., Musubire, A., Akampurira, A., Smith, K. D., Alhadab, A., Williams, D. A., Abassi, M., Bahr, N. C., Velamakanni, S. S., Fisher, J., Nielsen, K., Meya, D. B. & Boulware, D. R., Jul 1 2016, In: The Lancet Infectious Diseases. 16, 7, p. 809-818 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

137 Scopus citations

2015

Cryptococcal Meningitis: Diagnosis and Management Update

Abassi, M., Boulware, D. R. & Rhein, J., Jun 1 2015, In: Current Tropical Medicine Reports. 2, 2, p. 90-99 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

102 Scopus citations

Increased antifungal drug resistance in clinical isolates of Cryptococcus neoformans in Uganda

Smith, K. D., Achan, B., Hullsiek, K. H., McDonald, T. R., Okagaki, L. H., Alhadab, A. A., Akampurira, A., Rhein, J. R., Meya, D. B., Boulware, D. R., Nielsen, K., Musubire, A., Nabeta, H. W., Williams, D. A., Morawski, B., Rolfes, M. A., Ndyetukira, J. F., Ahimbisibwe, C., Kugonza, F., Sadiq, A., & 22 othersDyal, J., Neborak, J. M., King, A. M., Yueh, N., Velamakanni, S. S., Namudde, A., Kandole, T. K., Kaboggoza, J., Laker, E., Luggya, T., Tugume, L., Abassi, M., Birkenkamp, K., Butler, E. K., Fujita, A. W., Halupnick, R., Strain, A. K., Vedula, P., Rajasingham, R., Kambugu, A., Bohjanen, P. R. & on behalf of the ASTRO-CM/COAT Team, Dec 1 2015, In: Antimicrobial agents and chemotherapy. 59, 12, p. 7197-7204 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

142 Scopus citations

Mahsa Abassi

Research output

Search results