Research output per year
Research output per year
- 1 - 50 out of 181 results
Search results
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2024
Inducing positive inotropy in human iPSC-derived cardiac muscle by gene editing-based activation of the cardiac α-myosin heavy chain
Bedada, F. B., Thompson, B. R., Mikkila, J. L., Chan, S., Choi, S. H., Toso, E. A., Kyba, M. & Metzger, J. M., Dec 2024, In: Scientific reports. 14, 1, 3915.Research output: Contribution to journal › Article › peer-review
Open Access -
Skin muscle is the initial site of viral replication for arboviral bunyavirus infection
Schneider, C. A., Leung, J. M., Valenzuela-Leon, P. C., Golviznina, N. A., Toso, E. A., Bosnakovski, D., Kyba, M., Calvo, E. & Peterson, K. E., Dec 2024, In: Nature communications. 15, 1Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein
Bosnakovski, D., Toso, E. A., Ener, E. T., Gearhart, M. D., Yin, L., Lüttmann, F. F., Magli, A., Shi, K., Kim, J., Aihara, H. & Kyba, M., Oct 20 2023, In: iScience. 26, 10, 107823.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells
Ramabadran, R., Wang, J. H., Reyes, J. M., Guzman, A. G., Gupta, S., Rosas, C., Brunetti, L., Gundry, M. C., Tovy, A., Long, H., Gu, T., Cullen, S. M., Tyagi, S., Rux, D., Kim, J. J., Kornblau, S. M., Kyba, M., Stossi, F., Rau, R. E., Takahashi, K., & 2 others, Apr 2023, In: Nature Cell Biology. 25, 4, p. 528-539 12 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Erratum: Dual inhibition of MAPK and PI3K/AKT pathways enhances maturation of human iPSC-derived cardiomyocytes (Stem Cell Reports (2022) 17(9) (2005–2022), (S2213671122003629), (10.1016/j.stemcr.2022.07.003))
Garay, B. I., Givens, S., Abreu, P., Liu, M., Yücel, D., Baik, J., Stanis, N., Rothermel, T. M., Magli, A., Abrahante, J. E., Goloviznina, N. A., Soliman, H. A. N., Dhoke, N. R., Kyba, M., Alford, P. W., Dudley, S. C., van Berlo, J. H., Ogle, B. & Perlingeiro, R. R. C., Jan 10 2023, In: Stem Cell Reports. 18, 1, p. 411 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Facioscapulohumeral muscular dystrophy's game of homeodomains: therapy wants a biomarker as a sword wants a whetstone
Kyba, M. & Bosnakovski, D., 2023, In: Brain Communications. 5, 5, fcad235.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Genetically prolonged beige fat in male mice confers long-lasting metabolic health
Wu, R., Park, J., Qian, Y., Shi, Z., Hu, R., Yuan, Y., Xiong, S., Wang, Z., Yan, G., Ong, S. G., Song, Q., Song, Z., Mahmoud, A. M., Xu, P., He, C., Arpke, R. W., Kyba, M., Shu, G., Jiang, Q. & Jiang, Y., Dec 2023, In: Nature communications. 14, 1, 2731.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Proliferation and Maturation: Janus and the Art of Cardiac Tissue Engineering
Singh, B. N., Yucel, D., Garay, B. I., Tolkacheva, E. G., Kyba, M., Perlingeiro, R. C. R., Van Berlo, J. H. & Ogle, B. M., Feb 17 2023, In: Circulation research. 132, 4, p. 519-540 22 p.Research output: Contribution to journal › Review article › peer-review
7 Scopus citations -
The fibrotic niche impairs satellite cell function and muscle regeneration in mouse models of Marfan syndrome
Tomaz da Silva, M., Santos, A. R., Koike, T. E., Nascimento, T. L., Rozanski, A., Bosnakovski, D., Pereira, L. V., Kumar, A., Kyba, M. & Miyabara, E. H., Jan 2023, In: Acta Physiologica. 237, 1, e13889.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
The Satellite Cell Colony Forming Cell Assay as a Tool to Measure Self-Renewal and Differentiation Potential
Shams, A. S. & Kyba, M., 2023, Methods in Molecular Biology. Humana Press Inc., p. 45-55 11 p. (Methods in Molecular Biology; vol. 2640).Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
2022
Antiapoptotic Protein FAIM2 is targeted by miR-3202, and DUX4 via TRIM21, leading to cell death and defective myogenesis
Soliman, H. A. N., Toso, E. A., Darwish, I. E., Ali, S. M. & Kyba, M., Apr 2022, In: Cell Death and Disease. 13, 4, 405.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Baroreflex sensitivity in facioscapulohumeral muscular dystrophy
Anselmo, M., Coffman, S., Larson, M., Vera, K., Lee, E., McConville, M., Kyba, M. & Keller-Ross, M. L., Apr 2022, In: Physiological Reports. 10, 8, e15277.Research output: Contribution to journal › Article › peer-review
Open Access -
Corrigendum: Sarcopenic Obesity in Facioscapulohumeral Muscular Dystrophy (Front Physiol., (2020), 11, (1008), 10.3389/fphys.2020.01008)
Vera, K., McConville, M., Kyba, M. & Keller-Ross, M., Apr 28 2022, In: Frontiers in Physiology. 13, 908605.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Dual inhibition of MAPK and PI3K/AKT pathways enhances maturation of human iPSC-derived cardiomyocytes
Garay, B. I., Givens, S., Abreu, P., Liu, M., Yücel, D., Baik, J., Stanis, N., Rothermel, T. M., Magli, A., Abrahante, J. E., Goloviznina, N. A., Soliman, H. A. N., Dhoke, N. R., Kyba, M., Alford, P. W., Dudley, S. C., van Berlo, J. H., Ogle, B. & Perlingeiro, R. R. C., Sep 13 2022, In: Stem Cell Reports. 17, 9, p. 2005-2022 18 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Estradiol deficiency reduces the satellite cell pool by impairing cell cycle progression
Larson, A. A., Shams, A. S., Roloff, Z. A., Batchelor, E., Kyba, M., Lowe, D. A., McMillin, S. L., Sullivan, B. P. & Vue, C., Jun 2022, In: American Journal of Physiology - Cell Physiology. 322, 6, p. C1123-C1137Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Exercise Intolerance in Facioscapulohumeral Muscular Dystrophy
Vera, K. A., McConville, M., Glazos, A., Stokes, W., Kyba, M. & Keller-Ross, M., Jun 1 2022, In: Medicine and science in sports and exercise. 54, 6, p. 887-895 9 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages
Rowton, M., Perez-Cervantes, C., Hur, S., Jacobs-Li, J., Lu, E., Deng, N., Guzzetta, A., Hoffmann, A. D., Stocker, M., Steimle, J. D., Lazarevic, S., Oubaha, S., Yang, X. H., Kim, C., Yu, S., Eckart, H., Koska, M., Hanson, E., Chan, S. S. K., Garry, D. J., & 5 others, Sep 26 2022, In: Developmental Cell. 57, 18, p. 2181-2203.e9Research output: Contribution to journal › Article › peer-review
Open Access -
Laminin 411 mediates endothelial specification via multiple signaling axes that converge on β-catenin
Hall, M. L., Givens, S., Santosh, N., Iacovino, M., Kyba, M. & Ogle, B. M., Mar 8 2022, In: Stem Cell Reports. 17, 3, p. 569-583 15 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Not young but still immature: a HIF-1α-mediated maturation checkpoint in regenerating muscle
Salekeen, R. & Kyba, M., Dec 1 2022, In: Journal of Clinical Investigation. 132, 23, e165322.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
Persistent Fibroadipogenic Progenitor Expansion Following Transient DUX4 Expression Provokes a Profibrotic State in a Mouse Model for FSHD
Bosnakovski, D., Oyler, D., Mitanoska, A., Douglas, M., Ener, E. T., Shams, A. S. & Kyba, M., Feb 1 2022, In: International journal of molecular sciences. 23, 4, 1983.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
The chemokine receptor CXCR4 regulates satellite cell activation, early expansion, and self-renewal, in response to skeletal muscle injury
Shams, A. S., Arpke, R. W., Gearhart, M. D., Weiblen, J., Mai, B., Oyler, D., Bosnakovski, D., Mahmoud, O. M., Hassan, G. M. & Kyba, M., Sep 22 2022, In: Frontiers in Cell and Developmental Biology. 10, 949532.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Transplantation of PSC-derived myogenic progenitors counteracts disease phenotypes in FSHD mice
Azzag, K., Bosnakovski, D., Tungtur, S., Salama, P., Kyba, M. & Perlingeiro, R. C. R., Dec 2022, In: npj Regenerative Medicine. 7, 1, 43.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2021
B1 lymphocytes develop independently of Notch signaling during mouse embryonic development
Portilho, N. A., Scarfo, R., Bertesago, E., Ismailoglu, I., Kyba, M., Kobayashi, M., Ditadi, A. & Yoshimoto, M., Aug 2021, In: Development (Cambridge). 148, 15, dev199373.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Chromatin accessibility profiling identifies evolutionary conserved loci in activated human satellite cells
Chow, L. S., Bosnakovski, D., Mashek, D. G., Kyba, M., Perlingeiro, R. C. R. & Magli, A., Aug 2021, In: Stem Cell Research. 55, 102496.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Dux facilitates post-implantation development, but is not essential for zygotic genome activation
Bosnakovski, D., Gearhart, M. D., Ho Choi, S. & Kyba, M., Jan 1 2021, In: Biology of reproduction. 104, 1, p. 83-93 11 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Editorial overview – Differentiation: the driver of development
Echeverri, K. & Kyba, M., Dec 2021, In: Current Opinion in Cell Biology. 73, p. iii-vResearch output: Contribution to journal › Editorial › peer-review
Open Access -
Enhanced differentiation of human induced pluripotent stem cells toward the midbrain dopaminergic neuron lineage through GLYPICAN-4 downregulation
Corti, S., Bonjean, R., Legier, T., Rattier, D., Melon, C., Salin, P., Toso, E. A., Kyba, M., Kerkerian-Le Goff, L., Maina, F. & Dono, R., May 2021, In: Stem Cells Translational Medicine. 10, 5, p. 725-742 18 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Fli1 Promotes Vascular Morphogenesis by Regulating Endothelial Potential of Multipotent Myogenic Progenitors
Ferdous, A., Singh, S., Luo, Y., Abedin, M. J., Jiang, N., Perry, C. E., Evers, B. M., Gillette, T. G., Kyba, M., Trojanowska, M. & Hill, J. A., Oct 29 2021, In: Circulation research. 129, 10, p. 949-964 16 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma
Bosnakovski, D., Ener, E. T., Cooper, M. S., Gearhart, M. D., Knights, K. A., Xu, N. C., Palumbo, C. A., Toso, E. A., Marsh, G. P., Maple, H. J. & Kyba, M., Oct 2021, In: Oncogenesis. 10, 10, 68.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
In vitro expanded skeletal myogenic progenitors from pluripotent stem cell-derived teratomas have high engraftment capacity
Xie, N., Chu, S. N., Azzag, K., Schultz, C. B., Peifer, L. N., Kyba, M., Perlingeiro, R. C. R. & Chan, S. S. K., Dec 14 2021, In: Stem Cell Reports. 16, 12, p. 2900-2912 13 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Preservation of satellite cell number and regenerative potential with age reveals locomotory muscle bias
Arpke, R. W., Shams, A. S., Collins, B. C., Larson, A. A., Lu, N., Lowe, D. A. & Kyba, M., Dec 2021, In: Skeletal muscle. 11, 1, 22.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Resting metabolic rate in adults with facioscapulohumeral muscular dystrophy
Vera, K., McConville, M., Kyba, M. & Keller-Ross, M., 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 9, p. 1058-1064 7 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2020
Correction to: Tet3 regulates cellular identity and DNA methylation in neural progenitor cells (Cellular and Molecular Life Sciences, (2020), 77, 14, (2871-2883), 10.1007/s00018-019-03335-7)
Santiago, M., Antunes, C., Guedes, M., Iacovino, M., Kyba, M., Reik, W., Sousa, N., Pinto, L., Branco, M. R. & Marques, C. J., Jul 1 2020, In: Cellular and Molecular Life Sciences. 77, 14, p. 2885 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD
Klingler, C., Ashley, J., Shi, K., Stiefvater, A., Kyba, M., Sinnreich, M., Aihara, H. & Kinter, J., Mar 1 2020, In: FASEB Journal. 34, 3, p. 4573-4590 18 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Meeting report: the 2020 FSHD International Research Congress
Kyba, M., Bloch, R. J., Dumonceaux, J., Harper, S. Q., van der Maarel, S. M., Sverdrup, F. M., Wagner, K. R., van Engelen, B. & Chen, Y. W., Dec 2020, In: Skeletal muscle. 10, 1, 36.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Oestradiol affects skeletal muscle mass, strength and satellite cells following repeated injuries
Larson, A. A., Baumann, C. W., Kyba, M. & Lowe, D. A., Oct 1 2020, In: Experimental Physiology. 105, 10, p. 1700-1707 8 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Prospective isolation of human fibroadipogenic progenitors with CD73
Goloviznina, N. A., Xie, N., Dandapat, A., Iaizzo, P. A. & Kyba, M., Jul 2020, In: Heliyon. 6, 7, e04503.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Replication of bone-marrow pathophysiology
Kyba, M., Apr 1 2020, In: Nature Biomedical Engineering. 4, 4, p. 364-365 2 p.Research output: Contribution to journal › Article › peer-review
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Sarcopenic Obesity in Facioscapulohumeral Muscular Dystrophy
Vera, K. A., McConville, M., Kyba, M. & Keller-Ross, M. L., Aug 12 2020, In: Frontiers in Physiology. 11, 1008.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Tet3 regulates cellular identity and DNA methylation in neural progenitor cells
Santiago, M., Antunes, C., Guedes, M., Iacovino, M., Kyba, M., Reik, W., Sousa, N., Pinto, L., Branco, M. R. & Marques, C. J., Jul 1 2020, In: Cellular and Molecular Life Sciences. 77, 14, p. 2871-2883 13 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
Transcriptional and cytopathological hallmarks of FSHD in chronic DUX4-expressing mice
Bosnakovski, D., Shams, A. S., Yuan, C., da Silva, M. T., Ener, E. T., Baumann, C. W., Lindsay, A. J., Verma, M., Asakura, A., Lowe, D. A. & Kyba, M., May 1 2020, In: Journal of Clinical Investigation. 130, 5, p. 2465-2477 13 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
2019
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death
Bosnakovski, D., da Silva, M. T., Sunny, S. T., Ener, E. T., Toso, E. A., Yuan, C., Cui, Z., Walters, M. A., Jadhav, A. & Kyba, M., Sep 11 2019, In: Science Advances. 5, 9, eaaw7781.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Estrogen Regulates the Satellite Cell Compartment in Females
Collins, B. C., Arpke, R. W., Larson, A. A., Baumann, C. W., Xie, N., Cabelka, C. A., Nash, N. L., Juppi, H. K., Laakkonen, E. K., Sipilä, S., Kovanen, V., Spangenburg, E. E., Kyba, M. & Lowe, D. A., Jul 9 2019, In: Cell reports. 28, 2, p. 368-381.e6Research output: Contribution to journal › Article › peer-review
Open Access70 Scopus citations -
Pluripotent Stem Cell-Based Therapeutics for Muscular Dystrophies
Selvaraj, S., Kyba, M. & Perlingeiro, R. C. R., Sep 2019, In: Trends in Molecular Medicine. 25, 9, p. 803-816 14 p.Research output: Contribution to journal › Review article › peer-review
9 Scopus citations -
Pluripotent stem cell-derived myogenic progenitors remodel their molecular signature upon in vivo engraftment
Incitti, T., Magli, A., Darabi, R., Yuan, C., Lin, K., Arpke, R. W., Azzag, K., Yamamoto, A., Stewart, R., Thomson, J. A., Kyba, M. & Perlingeiro, R. C. R., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 10, p. 4346-4351 6 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
2018
A moderate oestradiol level enhances neutrophil number and activity in muscle after traumatic injury but strength recovery is accelerated
Le, G., Novotny, S. A., Mader, T. L., Greising, S. M., Chan, S. S. K., Kyba, M., Lowe, D. A. & Warren, G. L., Oct 1 2018, In: Journal of Physiology. 596, 19, p. 4665-4680 16 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
A moderate oestradiol level enhances neutrophil number and activity in muscle after traumatic injury but strength recovery is accelerated
Le, G. C., Novotny, S. A., Mader, T. L., Greising, S., Chan, S., Kyba, M., Lowe, D. A. & Warren, G. L., Oct 1 2018, In: Journal of Physiology. 596, 19, p. 4665-4680 16 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
A novel inducible mouse model of MLL-ENL -driven mixed-lineage acute leukemia
Stavropoulou, V., Almosailleakh, M., Royo, H., Spetz, J. F., Juge, S., Brault, L., Kopp, P., Iacovino, M., Kyba, M., Tzankov, A., Stadler, M. B., Cazzaniga, G., Peters, A. H. F. M. & Schwaller, J., Aug 1 2018, In: HemaSphere. 2, 4, e51.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Comment on structural basis of DUX4/IGH-driven transactivation
Aihara, H., Shi, K., Lee, J. K., Bosnakovski, D. & Kyba, M., Sep 1 2018, In: Leukemia. 32, 9, p. 2090-2092 3 p.Research output: Contribution to journal › Letter › peer-review
Open Access1 Scopus citations -
Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA
Lee, J. K., Bosnakovski, D., Toso, E. A., Dinh, T., Banerjee, S., Bohl, T. E., Shi, K., Orellana, K., Kyba, M. & Aihara, H., Dec 11 2018, In: Cell reports. 25, 11, p. 2955-2962.e3Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations