Projects per year
Personal profile
Expertise related to UN SDGs
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Nicholas M Levinson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects and Grants
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Time-resolved FRET-based allostery sensors for any protein kinase drug target
Levinson, N. M., Drake, J. M., Georg, G. & Thomas, D. D.
NIH NATIONAL CANCER INSTITUTE (NCI)
3/1/20 → 2/28/23
Project: Research project
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Decoding the dynamic mechanism of allosteric activation
NIH NIGMS NATL INST OF GENERAL
1/1/18 → 12/31/22
Project: Research project
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A novel time-resolved fluorescence-based high-throughput
Levinson, N. M. & Muretta, J. M.
NIH NATIONAL CANCER INSTITUTE (NCI)
8/1/17 → 7/31/20
Project: Research project
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Kinome-Wide Spectroscopic Study of Drug Binding Site Ele
NIH NIGMS NATL INST OF GENERAL
12/11/14 → 11/30/17
Project: Research project
Research output
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Allostery governs Cdk2 activation and differential recognition of CDK inhibitors
Majumdar, A., Burban, D., Muretta, J. M., Thompson, A. R., Engel, T. A., Rasmussen, D. M., Subrahmanian, M. V., Veglia, G., Thomas, D. D. & Levinson, N. M., 2021, (Accepted/In press) In: Nature Chemical Biology.Research output: Contribution to journal › Article › peer-review
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Cooperativity between Orthosteric Inhibitors and Allosteric Inhibitor 8-Anilino-1-Naphthalene Sulfonic Acid (ANS) in Cyclin-Dependent Kinase 2
Faber, E. B., Tian, D., Burban, D., Levinson, N. M., Hawkinson, J. E. & Georg, G. I., Jul 17 2020, In: ACS Chemical Biology. 15, 7, p. 1759-1764 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate
Edmund, A. B., Walseth, T. F., Levinson, N. M. & Potter, L. R., Jan 29 2019, In: Science signaling. 12, 566, aau5378.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
A dynamic mechanism for allosteric activation of aurora kinase a by activation loop phosphorylation
Ruff, E. F., Muretta, J. M., Thompson, A. R., Lake, E. W., Cyphers, S., Albanese, S. K., Hanson, S. M., Behr, J. M., Thomas, D. D., Chodera, J. D. & Levinson, N. M., Feb 21 2018, In: eLife. 7, e32766.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
An Open Library of Human Kinase Domain Constructs for Automated Bacterial Expression
Albanese, S. K., Parton, D. L., Işlk, M., Rodríguez-Laureano, L., Hanson, S. M., Behr, J. M., Gradia, S., Jeans, C., Levinson, N. M., Seeliger, M. A. & Chodera, J. D., Aug 7 2018, In: Biochemistry. 57, 31, p. 4675-4689 15 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations