Ping-Yee Law

Professor, Pharmacology

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13 Finished

Studies on the mechanism of OPRM1 biased agonism and in
Law, P. & Thomas, M. J.
NIH NIDA NATL INST ON DRUG AB
9/1/16 → 12/31/17
Project: Research project
Structural and Functions Studies of Mu Opiate Receptors:
Loh, H. H., Law, P. & Wei, L.
NIH NIDA NATL INST ON DRUG AB
3/1/16 → 12/31/18
Project: Research project
Discovery of new allosteric modulators that convert anta
Loh, H. H. & Law, P.
NIH NIDA NATL INST ON DRUG AB
6/1/13 → 5/31/15
Project: Research project
Studies on the mechanism of OPRM1 biased agonism and in
Law, P. & Thomas, M. J.
NIH NIDA NATL INST ON DRUG AB
9/15/12 → 8/31/16
Project: Research project
Basic Research Center on Molecular and Cell Biology of D
Loh, H. H. & Law, P.
NIH NIDA NATL INST ON DRUG AB
9/30/08 → 6/30/14
Project: Research project

214 Article
14 Review article
5 Chapter
3 Letter
More
- 2 Comment/debate
- 1 Short survey

Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice
Chao, P. K., Chang, H. F., Ou, L. C., Chuang, J. Y., Lee, P. T., Chang, W. T., Chen, S. C., Ueng, S. H., Hsu, J. T. A., Tao, P. L., Law, P. Y., Loh, H. H. & Yeh, S. H., Dec 1 2019, In: Scientific reports. 9, 1, 2405.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Scopus citations
The in vivo antinociceptive and μ-opioid receptor activating effects of the combination of N-phenyl-2′,4′-dimethyl-4,5′-bi-1,3-thiazol-2-amines and naloxone
Lin, S. Y., Kuo, Y. H., Tien, Y. W., Ke, Y. Y., Chang, W. T., Chang, H. F., Ou, L. C., Law, P. Y., Xi, J. H., Tao, P. L., Loh, H. H., Chao, Y. S., Shih, C., Chen, C. T., Yeh, S. H. & Ueng, S. H., Apr 1 2019, In: European Journal of Medicinal Chemistry. 167, p. 312-323 12 p.
Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Morphine regulates adult neurogenesis and contextual memory extinction via the PKCε/Prox1 pathway
Fan, W., Wang, H., Zhang, Y., Loh, H. H., Law, P. Y. & Xu, C., Oct 2018, In: Neuropharmacology. 141, p. 126-138 13 p.
Research output: Contribution to journal › Article › peer-review

Open Access
6 Scopus citations
1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4 H -indazol-4-one: A Novel Opioid Receptor Agonist with Less Accompanying Gastrointestinal Dysfunction than Morphine
Chao, P. K., Ueng, S. H., Ou, L. C., Yeh, T. K., Chang, W. T., Chang, H. F., Chen, S. C., Tao, P. L., Law, P. Y., Loh, H. H., Cheng, M. F., Chuang, J. Y., Chen, C. T., Shih, C. & Yeh, S. H., May 1 2017, In: Anesthesiology. 126, 5, p. 952-966 15 p.
Research output: Contribution to journal › Article › peer-review
6 Scopus citations
Differential regulation of mouse and human Mu opioid receptor gene depends on the single stranded DNA structure of its promoter and α-complex protein 1
Lee, D., Law, P., Ln, W., Loh, H. H., Song, K. Y. & Choi, H. S., May 1 2017, In: Biomedical Reports. 6, 5, p. 532-538
Research output: Contribution to journal › Article › peer-review

Open Access