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Reuben Harris

1994 …2024

Research activity per year

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Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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Collaborations and top research areas from the last five years

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  • Mesoscale DNA features impact APOBEC3A and APOBEC3B deaminase activity and shape tumor mutational landscapes

    Sanchez, A., Ortega, P., Sakhtemani, R., Manjunath, L., Oh, S., Bournique, E., Becker, A., Kim, K., Durfee, C., Temiz, N. A., Chen, X. S., Harris, R., Lawrence, M. S. & Buisson, R., Dec 2024, In: Nature communications. 15, 1, 2370.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance

    Caswell, D. R., Gui, P., Mayekar, M. K., Law, E. K., Pich, O., Bailey, C., Boumelha, J., Kerr, D. L., Blakely, C. M., Manabe, T., Martinez-Ruiz, C., Bakker, B., De Dios Palomino Villcas, J., I. Vokes, N., Dietzen, M., Angelova, M., Gini, B., Tamaki, W., Allegakoen, P., Wu, W., & 65 othersHumpton, T. J., Hill, W., Tomaschko, M., Lu, W. T., Haderk, F., Al Bakir, M., Nagano, A., Gimeno-Valiente, F., de Carné Trécesson, S., Vendramin, R., Barbè, V., Mugabo, M., Weeden, C. E., Rowan, A., McCoach, C. E., Almeida, B., Green, M., Gomez, C., Nanjo, S., Barbosa, D., Moore, C., Przewrocka, J., Black, J. R. M., Grönroos, E., Suarez-Bonnet, A., Priestnall, S. L., Zverev, C., Lighterness, S., Cormack, J., Olivas, V., Cech, L., Andrews, T., Rule, B., Jiao, Y., Zhang, X., Ashford, P., Durfee, C., Venkatesan, S., Temiz, N. A., Tan, L., Larson, L. K., Argyris, P. P., Brown, W. L., Yu, E. A., Rotow, J. K., Guha, U., Roper, N., Yu, J., Vogel, R. I., Thomas, N. J., Marra, A., Selenica, P., Yu, H., Bakhoum, S. F., Chew, S. K., Reis-Filho, J. S., Jamal-Hanjani, M., Vousden, K. H., McGranahan, N., Van Allen, E. M., Kanu, N., Harris, R. S., Downward, J., Bivona, T. G. & Swanton, C., Jan 2024, In: Nature Genetics. 56, 1, p. 60-73 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    4 Scopus citations

  • Acute expression of human APOBEC3B in mice results in RNA editing and lethality

    Alonso de la Vega, A., Temiz, N. A., Tasakis, R., Somogyi, K., Salgueiro, L., Zimmer, E., Ramos, M., Diaz-Jimenez, A., Chocarro, S., Fernández-Vaquero, M., Stefanovska, B., Reuveni, E., Ben-David, U., Stenzinger, A., Poth, T., Heikenwälder, M., Papavasiliou, N., Harris, R. S. & Sotillo, R., Dec 2023, In: Genome biology. 24, 1, 267.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Scopus citations

  • APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer

    McCann, J. L., Cristini, A., Law, E. K., Lee, S. Y., Tellier, M., Carpenter, M. A., Beghè, C., Kim, J. J., Sanchez, A., Jarvis, M. C., Stefanovska, B., Temiz, N. A., Bergstrom, E. N., Salamango, D. J., Brown, M. R., Murphy, S., Alexandrov, L. B., Miller, K. M., Gromak, N. & Harris, R. S., Oct 2023, In: Nature Genetics. 55, 10, p. 1721-1734 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    5 Scopus citations

  • APOBEC3 degradation is the primary function of HIV-1 Vif determining virion infectivity in the myeloid cell line THP-1

    Ikeda, T., Shimizu, R., Nasser, H., Carpenter, M. A., Cheng, A. Z., Brown, W. L., Sauter, D. & Harris, R. S., Aug 31 2023, In: mBio. 14, 4, p. e0078223

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Scopus citations
View all 222 Research outputs