Scott M Dehm

2024

Evolving copy number gains promote tumor expansion and bolster mutational diversification

Wang, Z., Xia, Y., Mills, L. J., Nikolakopoulos, A., Maeser, N., Dehm, S. M., Sheltzer, J. M. & Sun, R., Dec 2024, In: Nature communications. 15, 1, 2025.

Research output: Contribution to journal › Article › peer-review

Open Access

Stat5 induces androgen receptor (AR) gene transcription in prostate cancer and offers a druggable pathway to target AR signaling

Maranto, C., Sabharwal, L., Udhane, V., Pitzen, S. P., McCluskey, B., Qi, S., O’Connor, C., Devi, S., Johnson, S., Jacobsohn, K., Banerjee, A., Iczkowski, K. A., Wang, L., Dehm, S. M. & Nevalainen, M. T., Mar 2024, In: Science Advances. 10, 9, eadi2742.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

ALAN is a computational approach that interprets genomic findings in the context of tumor ecosystems

Bergom, H. E., Shabaneh, A., Day, A., Ali, A., Boytim, E., Tape, S., Lozada, J. R., Shi, X., Perez, C. J., McSweeney, S., Pitzen, S. P., Ludwig, M., Antonarakis, E. S., Drake, J. M., Dehm, S. M., Ryan, C., Wang, J. & Hwang, J., Dec 2023, In: Communications biology. 6, 1, 417.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Basal epithelial cells in prostate development, tumorigenesis, and cancer progression

Pitzen, S. P. & Dehm, S. M., 2023, In: Cell Cycle. 22, 11, p. 1303-1318 16 p.

Research output: Contribution to journal › Review article › peer-review

Co-evolution of AR gene copy number and structural complexity in endocrine therapy resistant prostate cancer

Zivanovic, A., Miller, J. T., Munro, S. A., Knutson, T. P., Li, Y., Passow, C. N., Simonaitis, P., Lynch, M., Oseth, L. A., Zhao, S. G., Feng, F. Y., Wikström, P., Corey, E., Morrissey, C., Henzler, C., Raphael, B. J. & Dehm, S. M., Sep 1 2023, In: NAR Cancer. 5, 3, zcad045.

Research output: Contribution to journal › Article › peer-review

Open Access

Computational drug discovery for castration-resistant prostate cancers through in vitro drug response modeling

Zhang, W., Lee, A. M., Jena, S., Huang, Y., Ho, Y., Tietz, K. T., Miller, C. R., Su, M. C., Mentzer, J., Ling, A. L., Li, Y., Dehm, S. M. & Huang, R. S., Apr 25 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 17, e2218522120.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Expression and Therapeutic Targeting of TROP-2 in Treatment-Resistant Prostate Cancer

Sperger, J. M., Helzer, K. T., Stahlfeld, C. N., Jiang, D., Singh, A., Kaufmann, K. R., Niles, D. J., Heninger, E., Rydzewski, N. R., Wang, L., Wang, L., Yang, R., Ren, Y., Engle, J. W., Huang, P., Kyriakopoulos, C. E., Slovin, S. F., Soule, H. R., Zhao, S. G., Kohli, M., & 4 othersTagawa, S. T., Cai, W., Dehm, S. M. & Lang, J. M., Jun 13 2023, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 29, 12, p. 2324-2335 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Fragmentomic analysis of circulating tumor DNA-targeted cancer panels

Helzer, K. T., Sharifi, M. N., Sperger, J. M., Shi, Y., Annala, M., Bootsma, M. L., Reese, S. R., Taylor, A., Kaufmann, K. R., Krause, H. K., Schehr, J. L., Sethakorn, N., Kosoff, D., Kyriakopoulos, C., Burkard, M. E., Rydzewski, N. R., Yu, M., Harari, P. M., Bassetti, M., Blitzer, G., & 14 othersFloberg, J., Sjöström, M., Quigley, D. A., Dehm, S. M., Armstrong, A. J., Beltran, H., McKay, R. R., Feng, F. Y., O'Regan, R., Wisinski, K. B., Emamekhoo, H., Wyatt, A. W., Lang, J. M. & Zhao, S. G., Sep 2023, In: Annals of Oncology. 34, 9, p. 813-825 13 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Prostate Cancer Progression Relies on the Mitotic Kinase Citron Kinase

Rawat, C., Ben-Salem, S., Singh, N., Chauhan, G., Rabljenovic, A., Vaghela, V., Venkadakrishnan, V. B., Macdonald, J. D., Dahiya, U. R., Ghanem, Y., Bachour, S., Su, Y., DePriest, A. D., Lee, S., Muldong, M., Kim, H. T., Kumari, S., Valenzuela, M. M., Zhang, D., Hu, Q., & 12 othersGomez, E. C., Dehm, S. M., Zoubeidi, A., Jamieson, C. A. M., Nicolas, M., McKenney, J., Willard, B., Klein, E. A., Magi-Galluzzi, C., Stauffer, S. R., Liu, S. & Heemers, H. V., Dec 15 2023, In: Cancer Research. 183, 24, p. 4142-4160 19 p.

Research output: Contribution to journal › Article › peer-review

Targeting the Androgen Signaling Axis in Prostate Cancer

Dai, C., Dehm, S. M. & Sharifi, N., Sep 10 2023, In: Journal of Clinical Oncology. 41, 26, p. 4267-4278 12 p.

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

2022

Molecular Profile Changes in Patients with Castrate-Resistant Prostate Cancer Pre- and Post-Abiraterone/Prednisone Treatment

Sicotte, H., Kalari, K. R., Qin, S., Dehm, S. M., Bhargava, V., Gormley, M., Tan, W., Sinnwell, J. P., Hillman, D. W., Li, Y., Vedell, P. T., Carlson, R. E., Bryce, A. H., Jimenez, R. E., Weinshilboum, R. M., Kohli, M. & Wang, L., Dec 2 2022, In: Molecular cancer research : MCR. 20, 12, p. 1739-1750 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2021

A pan-cancer transcriptome analysis of exitron splicing identifies novel cancer driver genes and neoepitopes

Wang, T., Liu, Q., Ren, Y., Alam, S. K., Wang, L., Zhu, Z., Hoeppner, L. H., Dehm, S. M., Cao, Q. & Yang, R., May 20 2021, In: Molecular Cell. 81, 10, p. 2246-2260.e12

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

AR gene rearrangement analysis in liquid biopsies reveals heterogeneity in lethal prostate cancer

Daniel, M., Knutson, T. P., Sperger, J. M., Li, Y., Singh, A., Stahlfeld, C. N., Passow, C., Auch, B., Lang, J. M. & Dehm, S. M., Aug 11 2021, In: Endocrine-related cancer. 28, 9, p. 645-655 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Increased transcription and high translation efficiency lead to accumulation of androgen receptor splice variant after androgen deprivation therapy

Ma, T., Bai, S., Qi, Y., Zhan, Y., Ungerleider, N., Zhang, D. Y., Neklesa, T., Corey, E., Dehm, S. M., Zhang, K., Flemington, E. K. & Dong, Y., Apr 28 2021, In: Cancer Letters. 504, p. 37-48 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

iRGD-Liposomes Enhance Tumor Delivery and Therapeutic Efficacy of Antisense Oligonucleotide Drugs against Primary Prostate Cancer and Bone Metastasis

Guan, J., Guo, H., Tang, T., Wang, Y., Wei, Y., Seth, P., Li, Y., Dehm, S. M., Ruoslahti, E. & Pang, H. B., Jun 9 2021, In: Advanced Functional Materials. 31, 24, 2100478.

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer

Che, M., Chaturvedi, A., Munro, S. A., Pitzen, S. P., Ling, A., Zhang, W., Mentzer, J., Ku, S. Y., Puca, L., Zhu, Y., Bergman, A. M., Severson, T. M., Forster, C., Liu, Y., Hildebrand, J., Daniel, M., Wang, T. Y., Selth, L. A., Hickey, T., Zoubeidi, A., & 14 othersGleave, M., Bareja, R., Sboner, A., Tilley, W., Carroll, J. S., Tan, W., Kohli, M., Yang, R., Hsieh, A. C., Murugan, P., Zwart, W., Beltran, H., Huang, R. S. & Dehm, S. M., Dec 2021, In: Nature communications. 12, 1, 6377.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Prospective Evaluation of Clinical Outcomes Using a Multiplex Liquid Biopsy Targeting Diverse Resistance Mechanisms in Metastatic Prostate Cancer

Sperger, J. M., Emamekhoo, H., McKay, R. R., Stahlfeld, C. N., Singh, A., Chen, X. E., Kwak, L., Gilsdorf, C. S., Wolfe, S. K., Wei, X. X., Silver, R., Zhang, Z., Morris, M. J., Bubley, G., Feng, F. Y., Scher, H. I., Rathkopf, D., Dehm, S. M., Choueiri, T. K., Halabi, S., & 5 othersArmstrong, A. J., Wyatt, A. W., Taplin, M. E., Zhao, S. G. & Lang, J. M., Sep 10 2021, In: Journal of Clinical Oncology. 39, 26, p. 2926-2937 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

Prostate Cancer Foundation Hormone-Sensitive Prostate Cancer Biomarker Working Group Meeting Summary

Hofmann, M. R., Hussain, M., Dehm, S. M., Beltran, H., Wyatt, A. W., Halabi, S., Sweeney, C., Scher, H. I., Ryan, C. J., Feng, F. Y., Attard, G., Klein, E., Miyahira, A. K., Soule, H. R. & Sharifi, N., Sep 2021, In: Urology. 155, p. 165-171 7 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

6 Scopus citations

Second-generation jak2 inhibitors for advanced prostate cancer: Are we ready for clinical development?

Beinhoff, P., Sabharwal, L., Udhane, V., Maranto, C., Laviolette, P. S., Jacobsohn, K. M., Tsai, S., Iczkowski, K. A., Wang, L., Hall, W. A., Dehm, S. M., Kilari, D. & Nevalainen, M. T., Oct 1 2021, In: Cancers. 13, 20, 5204.

Research output: Contribution to journal › Review article › peer-review

Open Access

11 Scopus citations

2020

Androgen receptor: Functional roles and facets of regulation in urology

Dehm, S. M. & Huang, H., Jul 2020, In: Asian Journal of Urology. 7, 3, p. 189-190 2 p.

Research output: Contribution to journal › Editorial › peer-review

Open Access

1 Scopus citations

Androgen receptor variants: RNA-based mechanisms and therapeutic targets

Tietz, K. T. & Dehm, S. M., Sep 15 2020, In: Human molecular genetics. 29, p. R19-R26

Research output: Contribution to journal › Review article › peer-review

Open Access

12 Scopus citations

Diverse AR gene rearrangements mediate resistance to androgen receptor inhibitors in metastatic prostate cancer

Li, Y., Yang, R., Henzler, C. M., Ho, Y., Passow, C., Auch, B., Carreira, S., Rodrigues, D. N., Bertan, C., Hwang, T. H., Quigley, D. A., Dang, H. X., Morrissey, C., Fraser, M., Plymate, S. R., PlymateMaher, C. A., Feng, F. Y., De Bono, J. S. & Dehm, S. M., Apr 15 2020, In: Clinical Cancer Research. 26, 8, p. 1965-1976 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

50 Scopus citations

Exploitation of CD133 for the Targeted Imaging of Lethal Prostate Cancer

Glumac, P. M., Gallant, J. P., Shapovalova, M., Li, Y., Murugan, P., Gupta, S., Coleman, I. M., Nelson, P. S., Dehm, S. M. & Lebeau, A. M., Mar 1 2020, In: Clinical Cancer Research. 26, 5, p. 1054-1064

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

SV-HotSpot: detection and visualization of hotspots targeted by structural variants associated with gene expression

Eteleeb, A. M., Quigley, D. A., Zhao, S. G., Pham, D., Yang, R., Dehm, S. M., Luo, J., Feng, F. Y., Dang, H. X. & Maher, C. A., Dec 1 2020, In: Scientific reports. 10, 1, 15890.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

The DNA methylation landscape of advanced prostate cancer

Zhao, S. G., Chen, W. S., Li, H., Foye, A., Zhang, M., Sjöström, M., Aggarwal, R., Playdle, D., Liao, A., Alumkal, J. J., Das, R., Chou, J., Hua, J. T., Barnard, T. J., Bailey, A. M., Chow, E. D., Perry, M. D., Dang, H. X., Yang, R., Moussavi-Baygi, R., & 49 othersZhang, L., Alshalalfa, M., Laura Chang, S., Houlahan, K. E., Shiah, Y. J., Beer, T. M., Thomas, G., Chi, K. N., Gleave, M., Zoubeidi, A., Reiter, R. E., Rettig, M. B., Witte, O., Yvonne Kim, M., Fong, L., Spratt, D. E., Morgan, T. M., Bose, R., Huang, F. W., Li, H., Chesner, L., Shenoy, T., Goodarzi, H., Asangani, I. A., Sandhu, S., Lang, J. M., Mahajan, N. P., Lara, P. N., Evans, C. P., Febbo, P., Batzoglou, S., Knudsen, K. E., He, H. H., Huang, J., Zwart, W., Costello, J. F., Luo, J., Tomlins, S. A., Wyatt, A. W., Dehm, S. M., Ashworth, A., Gilbert, L. A., Boutros, P. C., Farh, K., Chinnaiyan, A. M., Maher, C. A., Small, E. J., Quigley, D. A. & Feng, F. Y., Aug 1 2020, In: Nature Genetics. 52, 8, p. 778-789 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

173 Scopus citations

2019

Androgen Receptor Dependence

Chaturvedi, A. P. & Dehm, S. M., 2019, Advances in Experimental Medicine and Biology. Springer, p. 333-350 18 p. (Advances in Experimental Medicine and Biology; vol. 1210).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

20 Scopus citations

A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities

Kounatidou, E., Nakjang, S., McCracken, S. R. C., Dehm, S. M., Robson, C. N., Jones, D. & Gaughan, L., Jun 20 2019, In: Nucleic acids research. 47, 11, p. 5634-5647 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Scopus citations

A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

Warren, A. Y., Massie, C. E., Watt, K., Luko, K., Orafidiya, F., Selth, L. A., Mohammed, H., Chohan, B. S., Menon, S., Baridi, A., Zhao, W., Escriu, C., Pungsrinont, T., D’Santos, C., Yang, X., Taylor, C., Qureshi, A., Zecchini, V. R., Shaw, G. L., Dehm, S. M., & 7 othersMills, I. G., Carroll, J. S., Tilley, W. D., McEwan, I. J., Baniahmad, A., Neal, D. E. & Asim, M., Feb 14 2019, In: Oncogene. 38, 7, p. 1136-1150 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Ar-variant–positive CTC: A surrogate for a surrogate for taxane therapy outcome?

Dehm, S. M., Montgomery, B. & Plymate, S. R., 2019, In: Clinical Cancer Research. 25, 6, p. 1696-1698 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

CK2 pro-survival role in prostate cancer is mediated via maintenance and promotion of androgen receptor and NFκB p65 expression

Trembley, J. H., Kren, B. T., Abedin, M. J., Shaughnessy, D. P., Li, Y., Dehm, S. M. & Ahmed, K., Jun 2019, In: Pharmaceuticals. 12, 2, 89.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Correction: Exploiting the transcriptional specificity of the alphamethylacyl-CoA racemase AMACR promoter for the molecular imaging of prostate cancer (Oncotarget (2018) 9 (36693-36704) DOI: 10.18632/oncotarget.26401)

Shapovalova, M., Davydova, J., Henzler, C., Daniel, M., Dehm, S. M., Warlick, C. A. & LeBeau, A. M., Aug 1 2019, In: Oncotarget. 10, 47, p. 4920 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer

Zadra, G., Ribeiro, C. F., Chetta, P., Ho, Y., Cacciatore, S., Gao, X., Syamala, S., Bango, C., Photopoulos, C., Huang, Y., Tyekucheva, S., Bastos, D. C., Tchaicha, J., Lawney, B., Uo, T., D'Anello, L., Csibi, A., Kalekar, R., Larimer, B., Ellis, L., & 12 othersButler, L. M., Morrissey, C., McGovern, K., Palombella, V. J., Kutok, J. L., Mahmood, U., Bosari, S., Adams, J., Peluso, S., Dehm, S. M., Plymate, S. R. & Loda, M., Sep 2019, In: Journal of Urology. 202, 3, p. 460-461 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer

Zadra, G., Ribeiro, C. F., Chetta, P., Ho, Y., Cacciatore, S., Gao, X., Syamala, S., Bango, C., Photopoulos, C., Huang, Y., Tyekucheva, S., Bastos, D. C., Tchaicha, J., Lawney, B., Uo, T., D’Anello, L., Csibi, A., Kalekar, R., Larimer, B., Ellis, L., & 12 othersButler, L. M., Morrissey, C., McGovern, K., Palombella, V. J., Kutok, J. L., Mahmood, U., Bosari, S., Adams, J., Peluso, S., Dehm, S. M., Plymate, S. R. & Loda, M., Jan 8 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 2, p. 631-640 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

176 Scopus citations

PEG10 promoter-driven expression of reporter genes enables molecular imaging of lethal prostate cancer

Shapovalova, M., Lee, J. K., Li, Y., Griend, D. J. V., Coleman, I. M., Nelson, P. S., Dehm, S. M. & LeBeau, A. M., Nov 1 2019, In: Cancer Research. 79, 21, p. 5668-5680 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Preface

Dehm, S. M. & Tindall, D. J., Jan 1 2019, In: Advances in experimental medicine and biology. 1210, p. v-vi

Research output: Contribution to journal › Editorial › peer-review

Protein Kinase N1 control of androgen-responsive serum response factor action provides rationale for novel prostate cancer treatment strategy

Venkadakrishnan, V. B., DePriest, A. D., Kumari, S., Senapati, D., Ben-Salem, S., Su, Y., Mudduluru, G., Hu, Q., Cortes, E., Pop, E., Mohler, J. L., Azabdaftari, G., Attwood, K., Shah, R. B., Jamieson, C., Dehm, S. M., Magi-Galluzzi, C., Klein, E., Sharifi, N., Liu, S., & 1 othersHeemers, H. V., Jun 6 2019, In: Oncogene. 38, 23, p. 4496-4511 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

2018

A prospective genome-wide study of prostate cancer metastases reveals association of wnt pathway activation and increased cell cycle proliferation with primary resistance to abiraterone acetate-prednisone

Wang, L., Dehm, S. M., Hillman, D. W., Sicotte, H., Tan, W., Gormley, M., Bhargava, V., Jimenez, R., Xie, F., Yin, P., Qin, S., Quevedo, F., Costello, B. A., Pitot, H. C., Ho, T., Bryce, A. H., Ye, Z., Li, Y., Eiken, P., Vedell, P. T., & 16 othersBarman, P., McMenomy, B. P., Atwell, T. D., Carlson, R. E., Ellingson, M., Eckloff, B. W., Qin, R., Ou, F., Hart, S. N., Huang, H., Jen, J., Wieben, E. D., Kalari, K. R., Weinshilboum, R. M., Wang, L. & Kohli, M., Feb 1 2018, In: Annals of Oncology. 29, 2, p. 352-360 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

Erratum: Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer (Cell (2018) 174(3) (758–769.e9), (S0092867418308420) (10.1016/j.cell.2018.06.039))

Quigley, D. A., Dang, H. X., Zhao, S. G., Lloyd, P., Aggarwal, R., Alumkal, J. J., Foye, A., Kothari, V., Perry, M. D., Bailey, A. M., Playdle, D., Barnard, T. J., Zhang, L., Zhang, J., Youngren, J. F., Cieslik, M. P., Parolia, A., Beer, T. M., Thomas, G., Chi, K. N., & 43 othersGleave, M., Lack, N. A., Zoubeidi, A., Reiter, R. E., Rettig, M. B., Witte, O., Ryan, C. J., Fong, L., Kim, W., Friedlander, T., Chou, J., Li, H., Das, R., Li, H., Moussavi-Baygi, R., Goodarzi, H., Gilbert, L. A., Lara, P. N., Evans, C. P., Goldstein, T. C., Stuart, J. M., Tomlins, S. A., Spratt, D. E., Cheetham, R. K., Cheng, D. T., Farh, K., Gehring, J. S., Hakenberg, J., Liao, A., Febbo, P. G., Shon, J., Sickler, B., Batzoglou, S., Knudsen, K. E., He, H. H., Huang, J., Wyatt, A. W., Dehm, S. M., Ashworth, A., Chinnaiyan, A. M., Maher, C. A., Small, E. J. & Feng, F. Y., Oct 18 2018, In: Cell. 175, 3, p. 889 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

58 Scopus citations

Exploiting the transcriptional specificity of the alpha-methylacyl-CoA racemase AMACR promoter for the molecular imaging of prostate cancer

Shapovalova, M., Davydova, J., Henzler, C., Daniel, M., Dehm, S. M., Warlick, C. A. & LeBeau, A. M., Nov 30 2018, In: Oncotarget. 9, 94, p. 36693-36704 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer

Quigley, D. A., Dang, H. X., Zhao, S. G., Lloyd, P., Aggarwal, R., Alumkal, J. J., Foye, A., Kothari, V., Perry, M. D., Bailey, A. M., Playdle, D., Barnard, T. J., Zhang, L., Zhang, J., Youngren, J. F., Cieslik, M. P., Parolia, A., Beer, T. M., Thomas, G., Chi, K. N., & 43 othersGleave, M., Lack, N. A., Zoubeidi, A., Reiter, R. E., Rettig, M. B., Witte, O., Ryan, C. J., Fong, L., Kim, W., Friedlander, T., Chou, J., Li, H., Das, R., Li, H., Moussavi-Baygi, R., Goodarzi, H., Gilbert, L. A., Lara, P. N., Evans, C. P., Goldstein, T. C., Stuart, J. M., Tomlins, S. A., Spratt, D. E., Cheetham, R. K., Cheng, D. T., Farh, K., Gehring, J. S., Hakenberg, J., Liao, A., Febbo, P. G., Shon, J., Sickler, B., Batzoglou, S., Knudsen, K. E., He, H. H., Huang, J., Wyatt, A. W., Dehm, S. M., Ashworth, A., Chinnaiyan, A. M., Maher, C. A., Small, E. J. & Feng, F. Y., Jul 26 2018, In: Cell. 174, 3, p. 758-769.e9

Research output: Contribution to journal › Article › peer-review

Open Access

373 Scopus citations

Indel detection from DNA and RNA sequencing data with transIndel

Yang, R., Van Etten, J. L. & Dehm, S. M., Apr 19 2018, In: BMC Genomics. 19, 1, 270.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Inhibition of androgen receptor transactivation function by adenovirus type 12 E1A undermines prostate cancer cell survival

Li, D., Tian, G., Wang, J., Zhao, L. Y., Co, O., Underill, Z. C., Mymryk, J. S., Claessens, F., Dehm, S. M., Daaka, Y. & Liao, D., Nov 1 2018, In: Prostate. 78, 15, p. 1140-1156 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy

Lawrence, M. G., Obinata, D., Sandhu, S., Selth, L. A., Wong, S. Q., Porter, L. H., Lister, N., Pook, D., Pezaro, C. J., Goode, D. L., Rebello, R. J., Clark, A. K., Papargiris, M., Van Gramberg, J., Hanson, A. R., Banks, P., Wang, H., Niranjan, B., Keerthikumar, S., Hedwards, S., & 32 othersHuglo, A., Yang, R., Henzler, C., Li, Y., Lopez-Campos, F., Castro, E., Toivanen, R., Azad, A., Bolton, D., Goad, J., Grummet, J., Harewood, L., Kourambas, J., Lawrentschuk, N., Moon, D., Murphy, D. G., Sengupta, S., Snow, R., Thorne, H., Mitchell, C., Pedersen, J., Clouston, D., Norden, S., Ryan, A., Dehm, S. M., Tilley, W. D., Pearson, R. B., Hannan, R. D., Frydenberg, M., Furic, L., Taylor, R. A. & Risbridger, G. P., Nov 2018, In: European Urology. 74, 5, p. 562-572 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

74 Scopus citations

Prognostic association of plasma cell-free DNA-based androgen receptor amplification and circulating tumor cells in pre-chemotherapy metastatic castration-resistant prostate cancer patients

Kohli, M., Li, J., Du, M., Hillman, D. W., Dehm, S. M., Tan, W., Carlson, R., Campion, M. B., Wang, L., Wang, L., Zhang, H., Zhang, P., Kilari, D., Huang, C. C. & Wang, L., Sep 1 2018, In: Prostate Cancer and Prostatic Diseases. 21, 3, p. 411-418 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting

Luo, J., Attard, G., Balk, S. P., Bevan, C., Burnstein, K., Cato, L., Cherkasov, A., De Bono, J. S., Dong, Y., Gao, A. C., Gleave, M., Heemers, H., Kanayama, M., Kittler, R., Lang, J. M., Lee, R. J., Logothetis, C. J., Matusik, R., Plymate, S., Sawyers, C. L., & 7 othersSelth, L. A., Soule, H., Tilley, W., Weigel, N. L., Zoubeidi, A., Dehm, S. M. & Raj, G. V., May 2018, In: European Urology. 73, 5, p. 715-723 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

100 Scopus citations

Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing

PCF/SU2C International Prostate Cancer Dream Team, Jul 12 2018, In: Cell. 174, 2, p. 433-447.e19

Research output: Contribution to journal › Article › peer-review

Open Access

225 Scopus citations

2017

Androgen receptor rearrangement and splicing variants in resistance to endocrine therapies in prostate cancer

Ho, Y. & Dehm, S. M., Jun 1 2017, In: Endocrinology. 158, 6, p. 1533-1542 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

53 Scopus citations

Androgen receptor variant AR-V9 is coexpressed with AR-V7 in prostate cancer metastases and predicts abiraterone resistance

Kohli, M., Ho, Y., Hillman, D. W., Van Etten, J. L., Henzler, C., Yang, R., Sperger, J. M., Li, Y., Tseng, E., Hon, T., Clark, T., Tan, W., Carlson, R. E., Wang, L., Sicotte, H., Thai, H., Jimenez, R., Huang, H., Vedell, P. T., Eckloff, B. W., & 9 othersQuevedo, J. F., Pitot, H. C., Costello, B. A., Jen, J., Wieben, E. D., Silverstein, K. A. T., Lang, J. M., Wang, L. & Dehm, S. M., Aug 15 2017, In: Clinical Cancer Research. 23, 16, p. 4704-4715 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

106 Scopus citations

Androgen receptor variants mediate DNA repair after prostate cancer irradiation

Yin, Y., Li, R., Xu, K., Ding, S., Li, J., Baek, G. H., Ramanand, S. G., Ding, S., Liu, Z., Gao, Y., Kanchwala, M. S., Li, X., Hutchinson, R., Liu, X., Woldu, S. L., Xing, C., Desai, N. B., Feng, F. Y., Burma, S., De Bono, J. S., & 4 othersDehm, S. M., Mani, R. S., Chen, B. P. C. & Raj, G. V., Sep 15 2017, In: Cancer Research. 77, 18, p. 4745-4754 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

Androgen receptor variants mediate DNA repair after prostate cancer irradiation

Yin, Y., Li, R., Xu, K., Ding, S., Li, J., Baek, G. H., Ramanand, S. G., Ding, S., Liu, Z., Gao, Y., Kanchwala, M. S., Li, X., Hutchinson, R., Liu, X., Woldu, S. L., Xing, C., Desai, N. B., Feng, F. Y., Burma, S., De Bono, J. S., & 4 othersDehm, S. M., Mani, R. S., Chen, B. P. C. & Raj, G. V., Sep 15 2017, In: Cancer Research. 77, 18, p. 4745-4754 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

51 Scopus citations

Scott M Dehm

Research output

Search results