Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Postdoctoral Research in Immunology and Cell Signaling, UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
Sep 2007 → Jul 2014
PhD, Graduate Research in Molecular and Cell Biology, UNIVERSITY OF CALIFORNIA, BERKELEY
Aug 2001 → May 2007
BA, Undergraduate Degree in Biochemistry, Bowdoin College
Aug 1995 → May 1999
Research interests
- myeloid cells
- immunology
- autoimmune disease
- tumor micro
- biochemistry
- tyrosine kinase signaling
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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LynB kinase, TLR signaling, dendritic cells, and lupus
RHEUMATOLOGY RESEARCH FOUNDATION
7/1/22 → 6/30/24
Project: Research project
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Roles of the Src-family kinases LynA and LynB in macrophage inflammatory signaling
Freedman, T. & Binstadt, B. A.
NIH NIAMS NATL INST OF ARTHRIT
9/1/18 → 8/31/24
Project: Research project
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Roles of the Src-Family Kinases LynA and LynB in Macrophage Inflammatory Signaling
National Institute of Arthritis and Musculoskeletal and Skin Diseases
9/1/18 → 8/31/23
Project: Research project
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Generating LynA-/- and LynB-/- mice by CRISPR/Cas9 genom
NIH Nat'l Inst of Allergy & Infect Dis
1/15/17 → 12/31/18
Project: Research project
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Generating LynA-/- and LynB-/- mice by CRISPR/Cas9 genome editing
National Institute of Allergy and Infectious Diseases
1/15/17 → 12/31/18
Project: Research project
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Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells
Brian, B. F., Jolicoeur, A. S., Guerrero, C. R., Nunez, M. G., Sychev, Z. E., Hegre, S. A., Sætrom, P., Habib, N., Drake, J. M., Schwertfeger, K. L. & Freedman, T. S., Jul 2019, In: eLife. 8, e46043.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Primary infection with Zika virus provides one-way heterologous protection against Spondweni virus infection in rhesus macaques
Jaeger, A. S., Crooks, C. M., Weiler, A. M., Bliss, M. I., Rybarczyk, S., Richardson, A., Einwalter, M., Peterson, E., Capuano, S., Barkhymer, A., Becker, J. T., Greene, J. T., Freedman, T. S., Langlois, R. A., Friedrich, T. C. & Aliota, M. T., Jun 2023, In: Science Advances. 9, 26, eadg3444.Research output: Contribution to journal › Article › peer-review
Open Access -
ZBTB7A as a novel vulnerability in neuroendocrine prostate cancer
Bae, S. Y., Bergom, H. E., Day, A., Greene, J. T., Sychev, Z. E., Larson, G., Corey, E., Plymate, S. R., Freedman, T. S., Hwang, J. H. & Drake, J. M., 2023, In: Frontiers in Endocrinology. 14, 1093332.Research output: Contribution to journal › Article › peer-review
Open Access -
A dominant function of LynB kinase in preventing autoimmunity
Brian IV, B. F., Sauer, M. L., Greene, J. T., Senevirathne, S. E., Lindstedt, A. J., Funk, O. L., Ruis, B. L., Ramirez, L. A., Auger, J. L., Swanson, W. L., Nunez, M. G., Moriarity, B. S., Lowell, C. A., Binstadt, B. A. & Freedman, T. S., Apr 2022, In: Science Advances. 8, 16, abj5227.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
SH3-domain mutations selectively disrupt Csk homodimerization or PTPN22 binding
Brian, B. F., Sjaastad, F. V. & Freedman, T. S., Dec 2022, In: Scientific reports. 12, 1, 5875.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations