Projects per year
Personal profile
Research interests
I have a broad background in bioinformatics researchers. The focus of my graduate thesis is the application of comparative genomics and data mining methods to understand the regulatory sequences in mammalian genomes. After graduation, I have worked at MSI with an emphasis on projects using next-generation sequencing technologies. I have analyzed RNA-Seq, DNA-Seq, and ChIP-Seq data to profile gene expression, identify genomic variants and discover non-coding regulatory elements.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research interests
- next-generation sequencing
- bioinformatics
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Molecular mechanisms and consequences of Purkinje cell vulnerability in SCA1
NATIONAL ATAXIA FOUNDATION, INC.
3/1/22 → 2/28/23
Project: Research project
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Angiotensin-converting enzyme gates brain circuit–specific plasticity via an endogenous opioid
Trieu, B. H., Remmers, B. C., Toddes, C., Brandner, D. D., Lefevre, E. M., Kocharian, A., Retzlaff, C. L., Dick, R. M., Mashal, M. A., Gauthier, E. A., Xie, W., Zhang, Y., More, S. S. & Rothwell, P. E., Mar 11 2022, In: Science. 375, 6585, p. 1177-1182 6 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in huntington’s disease
Yu, D., Zarate, N., White, A., Coates, D., Tsai, W., Nanclares, C., Cuccu, F., Yue, J. S., Brown, T. G., Mansky, R. H., Jiang, K., Kim, H., Nichols-Meade, T., Larson, S. N., Gundry, K., Zhang, Y., Tomas-Zapico, C., Lucas, J. J., Benneyworth, M., Öz, G., & 3 others, Dec 2022, In: Acta Neuropathologica Communications. 10, 1, 83.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Correction to: CK2 alpha prime and alpha-synuclein pathogenic functional interaction mediates synaptic dysregulation in Huntington’s disease (Acta Neuropathologica Communications, (2022), 10, 1, (83), 10.1186/s40478-022-01379-8)
Yu, D., Zarate, N., White, A., Coates, D., Tsai, W., Nanclares, C., Cuccu, F., Yue, J. S., Brown, T. G., Mansky, R. H., Jiang, K., Kim, H., Nichols‑Meade, T., Larson, S. N., Gundry, K., Zhang, Y., Tomas‑Zapico, C., Lucas, J. J., Benneyworth, M., Öz, G., & 3 others, Dec 2022, In: Acta Neuropathologica Communications. 10, 1, 89.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Single nuclei RNA sequencing investigation of the Purkinje cell and glial changes in the cerebellum of transgenic Spinocerebellar ataxia type 1 mice
Borgenheimer, E., Hamel, K., Sheeler, C., Moncada, F. L., Sbrocco, K., Zhang, Y. & Cvetanovic, M., Nov 15 2022, In: Frontiers in Cellular Neuroscience. 16, 998408.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
The genome of the zebra mussel, Dreissena polymorpha: a resource for comparative genomics, invasion genetics, and biocontrol
McCartney, M. A., Auch, B., Kono, T., Mallez, S., Zhang, Y., Obille, A., Becker, A., Abrahante, J. E., Garbe, J., Badalamenti, J. P., Herman, A., Mangelson, H., Liachko, I., Sullivan, S., Sone, E. D., Koren, S., Silverstein, K. A. T., Beckman, K. B. & Gohl, D. M., Feb 2022, In: G3: Genes, Genomes, Genetics. 12, 2, jkab423.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations