Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Molecular Biology
1988 → 1994
Research interests
- Transgenic Mice Core Facility
- Mouse In Vitro Fertilization
- CRISPR/Cas9 genome engineering
- Generating transgenic mice
- Mouse Genetics
- Mouse Colony Management
- Molecular Biology
- Mouse Embryonic Stem Cell
- Genome Editing
- Mouse Sperm Cryopreservation
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Collaborations and top research areas from the last five years
Projects and Grants
- 1 Finished
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FUNCTIONAL MAPPING OF THE MOUSE T COMPLEX
National Institute of Child Health and Human Development
9/28/96 → 1/31/98
Project: Research project
Research output
- 20 Article
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Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles
Handler, H. P., Duvick, L., Mitchell, J. S., Cvetanovic, M., Reighard, M., Soles, A., Mather, K. B., Rainwater, O., Serres, S., Nichols-Meade, T., Coffin, S. L., You, Y., Ruis, B. L., O'Callaghan, B., Henzler, C., Zoghbi, H. Y. & Orr, H. T., Feb 15 2023, In: Neuron. 111, 4, p. 493-507.e6Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Generation and characterization of an immunodeficient mouse model of mucopolysaccharidosis type II
Smith, M. C., Belur, L. R., Karlen, A. D., Podetz-Pedersen, K., Erlanson, O., Laoharawee, K., Furcich, J., Lund, T. C., You, Y., Seelig, D., Webber, B. R. & McIvor, R. S., Apr 2023, In: Molecular Genetics and Metabolism. 138, 4, 107539.Research output: Contribution to journal › Article › peer-review
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Germline T cell receptor exchange results in physiological T cell development and function
Rollins, M. R., Raynor, J. F., Miller, E. A., Butler, J. Z., Spartz, E. J., Lahr, W. S., You, Y., Burrack, A. L., Moriarity, B. S., Webber, B. R. & Stromnes, I. M., Dec 2023, In: Nature communications. 14, 1, 528.Research output: Contribution to journal › Article › peer-review
Open Access -
Generation of inner ear sensory neurons using blastocyst complementation in a Neurog1 +/−−deficient mouse
Steevens, A. R., Griesbach, M. W., You, Y., Dutton, J. R., Low, W. C. & Santi, P. A., Dec 2021, In: Stem Cell Research and Therapy. 12, 1, 122.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Liver development is restored by blastocyst complementation of HHEX knockout in mice and pigs
Ruiz-Estevez, M., Crane, A. T., Rodriguez-Villamil, P., Ongaratto, F. L., You, Y., Steevens, A. R., Hill, C., Goldsmith, T., Webster, D. A., Sherry, L., Lim, S., Denman, N., Low, W. C., Carlson, D. F., Dutton, J. R., Steer, C. J. & Gafni, O., Dec 2021, In: Stem Cell Research and Therapy. 12, 1, 292.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations