Abstract
2-Aza-1,3-dienes, prepared in excellent yields from aldehydes and readily available allylamine, were utilized to synthesize N-(1-propenyl)-β-lactams. Oxidative cleavage of the N-protecting group produced N-unsubstituted β-lactams. 4-Acetoxy-3-phenoxy-2-azetidinone was synthesized in three steps and 34% overall yield.
Original language | English (US) |
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Pages (from-to) | 2409-2412 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 29 |
Issue number | 20 |
DOIs | |
State | Published - 1988 |
Externally published | Yes |
Bibliographical note
Funding Information:ACkUX#leageoents: Financial assistance fran the National Institutes of The American Heart Association of Kansas (KS-87-G-17) and the Bianedical 5606) at the University of Kansas is acknowledged.