TY - JOUR
T1 - 21-Deoxycortisone (17a-hydroxy-4-pregnene-3,11,20-trione)
AU - Dey, Raja
AU - Langer, Vratislav
AU - Roychowdhury, P.
AU - Roychowdhury, S.
AU - Drew, M. G.B.
PY - 2005/4
Y1 - 2005/4
N2 - The title compound, C21H28O4, a synthetic glucocorticoid, crystallizes with a single molecule in the asymmetric unit. Ring A is almost in a half-chair conformation, rings B and C are almost in chair conformations, and ring D is between a twist and a 13β-envelope conformation. The A/B ring junction is quasi-trans, whereas the B/C and C/D ring junctions both approach trans characteristics. The molecule as a whole is slightly convex towards the β side, with an angle of 9.60 (2)° between the C10-C19 and C13-C18 vectors. Molecular-packing and hydrogen-bonding (both intra- and intermolecular) interactions play a major role in the structural association of the compound.
AB - The title compound, C21H28O4, a synthetic glucocorticoid, crystallizes with a single molecule in the asymmetric unit. Ring A is almost in a half-chair conformation, rings B and C are almost in chair conformations, and ring D is between a twist and a 13β-envelope conformation. The A/B ring junction is quasi-trans, whereas the B/C and C/D ring junctions both approach trans characteristics. The molecule as a whole is slightly convex towards the β side, with an angle of 9.60 (2)° between the C10-C19 and C13-C18 vectors. Molecular-packing and hydrogen-bonding (both intra- and intermolecular) interactions play a major role in the structural association of the compound.
UR - http://www.scopus.com/inward/record.url?scp=30744460129&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=30744460129&partnerID=8YFLogxK
U2 - 10.1107/S0108270105003756
DO - 10.1107/S0108270105003756
M3 - Article
C2 - 15805624
AN - SCOPUS:30744460129
SN - 0108-2701
VL - 61
SP - o201-o203
JO - Acta Crystallographica Section C: Crystal Structure Communications
JF - Acta Crystallographica Section C: Crystal Structure Communications
IS - 4
ER -