A cost analysis of bone morphogenetic protein versus autogenous iliac crest bone graft in single-level anterior lumbar fusion

David W. Polly, Stacey J. Ackerman, Christopher I. Shaffrey, James W. Ogilvie, Jeffrey C. Wang, Susan W. Stralka, Michael S. Mafilios, Stephen E. Heim, Harvinder S. Sandhu

Research output: Contribution to journalArticlepeer-review

69 Scopus citations

Abstract

An economic model was developed to compare costs of stand-alone anterior lumbar interbody fusion with recombinant human bone morphogenetic protein 2 on an absorbable collagen sponge versus autogenous iliac crest bone graft in a tapered cylindrical cage or a threaded cortical bone dowel. The economic model was developed from clinical trial data, peer-reviewed literature, and clinical expert opinion. The upfront price of bone morphogenetic protein ($3380) is likely to be offset to a significant extent by reductions in the use of other medical resources, particularly if costs incurred during the 2-year period following the index hospitalization are taken into account.

Original languageEnglish (US)
Pages (from-to)1027-1037
Number of pages11
JournalOrthopedics
Volume26
Issue number10
StatePublished - Oct 1 2003

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