Abstract
Late presentation and ineffective phototherapy account for excessive rates of avoidable exchange transfusions (ETs) in many low-and middle-income countries. Several system-based constraints sometimes limit the ability to provide timely ETs for all infants at risk of kernicterus, thus necessitating a treatment triage to optimize available resources. This article proposes a practical priority-setting model for term and near-term infants requiring ET after the first 48 h of life. The proposed model combines plasma/serum bilirubin estimation, clinical signs of acute bilirubin encephalopathy and neurotoxicity risk factors for predicting the risk of kernicterus based on available evidence in the literature.
Original language | English (US) |
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Pages (from-to) | 338-341 |
Number of pages | 4 |
Journal | Journal of Perinatology |
Volume | 36 |
Issue number | 5 |
DOIs | |
State | Published - May 1 2016 |
Bibliographical note
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