A detection system based on giant magnetoresistive sensors and high-moment magnetic nanoparticles demonstrates zeptomole sensitivity: Potential for personalized medicine

Balasubramanian Srinivasan; Yuanpeng Li; Ying Jing; Yun Hao Xu; Xiaofeng Yao; Chengguo Xing; Jian Ping Wang

doi:10.1002/anie.200806266

A detection system based on giant magnetoresistive sensors and high-moment magnetic nanoparticles demonstrates zeptomole sensitivity: Potential for personalized medicine

Balasubramanian Srinivasan, Yuanpeng Li, Ying Jing, Yun Hao Xu, Xiaofeng Yao, Chengguo Xing, Jian Ping Wang

Research output: Contribution to journal › Article › peer-review

117 Scopus citations

Abstract

Zeptomole detector: A highly sensitive giantmagnetoresistive chip and FeCo nanoparticles can be used to linearly detect 600-4500 copies of streptavidin. Under unoptimized conditions, this system also detects human IL- 6 with a sensitivity 13-times higher than that of standard ELISA techniques.

Original language	English (US)
Pages (from-to)	2764-2767
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	48
Issue number	15
DOIs	https://doi.org/10.1002/anie.200806266
State	Published - Mar 30 2009

Keywords

Biosensors
Giant magnetoresistance
Nanoparticles
Proteins

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A detection system based on giant magnetoresistive sensors and high-moment magnetic nanoparticles demonstrates zeptomole sensitivity: Potential for personalized medicine. / Srinivasan, Balasubramanian; Li, Yuanpeng; Jing, Ying et al.
In: Angewandte Chemie - International Edition, Vol. 48, No. 15, 30.03.2009, p. 2764-2767.

Research output: Contribution to journal › Article › peer-review

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A detection system based on giant magnetoresistive sensors and high-moment magnetic nanoparticles demonstrates zeptomole sensitivity: Potential for personalized medicine

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