@inproceedings{0806e853948c439da680fcddd09318ed,
title = "A method to measure taste qualities, taste intensity, and temporal profile of compounds aimed at human consumption by taste nerve recordings in monkeys",
abstract = "A method is described to measure taste qualities and intensity of compounds aimed at human consumption by recording from taste nerve fibers of monkeys. Here we demonstrate its usefulness by presenting results of a comparison of sweetness of brazzein derivatives and bitterness of denatonium benzoate analogs as assessed by a human taste panel and recorded from monkey single taste fibers. The correlation between the responses in sweet sensitive fibers in monkeys and the estimates of sweetness by a human taste panel was 0.78 for 25 analogs of the sweet protein brazzein, and 0.9 between the responses of bitter sensitive fibers and human bitterness estimates for 6 analogs of the bitter compound denatonium benzoate.",
author = "Hellekant, {Goran B} and Yiwen Wang",
year = "2008",
month = mar,
day = "4",
doi = "10.1021/bk-2008-0979.ch013",
language = "English (US)",
isbn = "9780841274327",
series = "ACS Symposium Series",
publisher = "American Chemical Society",
pages = "185--201",
booktitle = "Sweetness and Sweeteners",
address = "United States",
}