@inproceedings{71ff208ca88f470cb09507b10532c6ac,
title = "A microfludic platform to probe the role of pericellular matrix in metastatic extravasation and invasion of breast cancer epithelial cells",
abstract = "A major barrier to studying the factors that influence the later stages of metastasis including extravasation and invasion of the metastatic site, is the lack of appropriate model systems that allow the quantification of metastatic progression in real time. To investigate the later stages of metastasis, we have developed a novel microfluidic platform that allows us to directly quantify the effect of individual factors on metastatic progression, specifically, the hyaluronan rich pericellular coat, known to promote tumor growth and metastasis. Using this model system, the influence of this coat on cancer cell adhesion, transmigration, and invasion was measured.",
keywords = "Extravasation, Hyaluronan, Metastasis, Pericellular coat",
author = "Brett, {Marie Elena} and Bomberger, {Heather E.} and Doak, {Geneva R.} and Price, {Matthew A.} and McCarthy, {James B.} and Wood, {David K.}",
year = "2020",
month = jan,
day = "1",
language = "English (US)",
series = "21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017",
publisher = "Chemical and Biological Microsystems Society",
pages = "1477--1478",
booktitle = "21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017",
note = "21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 ; Conference date: 22-10-2017 Through 26-10-2017",
}
