A novel and efficient algorithm for de novo discovery of mutated driver pathways in cancer

Mathematics

• Driver 100%
• Pathway 91%
• Cancer 78%
• Mutation 76%
• Efficient Algorithms 65%
• Tumor 40%
• Gradient Descent Method 28%
• Nonconvex Programming 27%
• Atlas 25%
• Gene Expression Data 25%
• Indicator function 24%
• Discontinuous Functions 23%
• Sequencing 22%
• Combinatorial Optimization 21%
• Genome 21%
• Optimization Algorithm 20%
• Overlap 19%
• Coverage 18%
• Newton Methods 18%
• Enumeration 17%
• Higher Dimensions 17%
• Regularization 16%
• Objective function 15%
• Tend 14%
• Formulation 12%
• Demonstrate 11%
• Performance 11%
• Concepts 9%

Business & Economics

• Cancer 90%
• Pathway 74%
• Mutation 71%
• Tumor 43%
• Gene Expression 21%
• Regularization 19%
• Combinatorial Optimization 19%
• Exclusivity 19%
• Sequencing 16%
• Gradient 16%
• Programming 14%
• Objective Function 14%
• Performance 5%

Engineering & Materials Science

• Tumors 52%
• Steepest descent method 32%
• Newton-Raphson method 28%
• Gene expression 27%
• Combinatorial optimization 27%
• Genomics 26%