TY - JOUR
T1 - A prospective, randomized, controlled, multicenter evaluation of extraction socket preservation comparing two bovine xenografts
T2 - Clinical and histologic outcomes
AU - Barone, Antonio
AU - Todisco, Marzio
AU - Ludovichetti, Maurizio
AU - Gualini, Federico
AU - Aggstaller, Hans
AU - Torrés-Lagares, Daniel
AU - Rohrer, Michael D.
AU - Prasad, Hari S.
AU - Kenealy, James N.
PY - 2013/1/1
Y1 - 2013/1/1
N2 - The aim of this prospective, randomized, controlled, multicenter study was to evaluate and compare the histologic and histomorphometric aspects of extraction sockets grafted with two commercially available bovine bone xenografts: Endobon (test group) and Bio-Oss (control group). The study was designed to ensure that baseline variables between groups were as similar as possible to allow for a direct comparison of graft healing characteristics. Thirty-eight patients contributed 62 augmented extraction sites to the study. All sites were grafted with one type of bovine bone mineral and covered with a resorbable collagen membrane for 6 months of healing prior to implant placement surgery. The histologic outcomes between the two treatment groups are similar, with de novo bone (mean ± SD) for the test group at 28.5% ± 20% and for the control group, 31.4% ± 18%. Histologic specimens also include membrane remnants. All but two implants integrated successfully after 1 year of follow-up. This investigation provides support for the efficacy of bovine bone xenograft for socket preservation when subsequent implant placement is planned.
AB - The aim of this prospective, randomized, controlled, multicenter study was to evaluate and compare the histologic and histomorphometric aspects of extraction sockets grafted with two commercially available bovine bone xenografts: Endobon (test group) and Bio-Oss (control group). The study was designed to ensure that baseline variables between groups were as similar as possible to allow for a direct comparison of graft healing characteristics. Thirty-eight patients contributed 62 augmented extraction sites to the study. All sites were grafted with one type of bovine bone mineral and covered with a resorbable collagen membrane for 6 months of healing prior to implant placement surgery. The histologic outcomes between the two treatment groups are similar, with de novo bone (mean ± SD) for the test group at 28.5% ± 20% and for the control group, 31.4% ± 18%. Histologic specimens also include membrane remnants. All but two implants integrated successfully after 1 year of follow-up. This investigation provides support for the efficacy of bovine bone xenograft for socket preservation when subsequent implant placement is planned.
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U2 - 10.11607/prd.1690
DO - 10.11607/prd.1690
M3 - Article
C2 - 24116363
AN - SCOPUS:84931096408
SN - 0198-7569
VL - 33
SP - 795
EP - 802
JO - International Journal of Periodontics and Restorative Dentistry
JF - International Journal of Periodontics and Restorative Dentistry
IS - 6
ER -