A putative monooxygenase mimic which functions via well-disguised free radical chemistry

Philip A. MacFaul; K. U. Ingold; D. D M Wayner; Lawrence Que

doi:10.1021/ja963627j

A putative monooxygenase mimic which functions via well-disguised free radical chemistry

Philip A. MacFaul, K. U. Ingold, D. D M Wayner, Lawrence Que

Chemistry (Twin Cities)

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160 Scopus citations

Abstract

The hydroxylation of cycloalkanes at 25°C by the syringe pump addition of tert-alkyl hydroperoxides (10 and 1 equiv based on catalyst) to deoxygenated acetonitrile containing cycloalkanes (0.64 M) and 0.61 mM of the catalyst, [Fem(III)₂O(TPA)₂(H₂O)₂]⁴⁺, is demonstrated to be a reaction which involves freely diffusing cycloalkyl radicals, i.e., free alkyl radicals.

Original language	English (US)
Pages (from-to)	10594-10598
Number of pages	5
Journal	Journal of the American Chemical Society
Volume	119
Issue number	44
DOIs	https://doi.org/10.1021/ja963627j
State	Published - 1997

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title = "A putative monooxygenase mimic which functions via well-disguised free radical chemistry",

abstract = "The hydroxylation of cycloalkanes at 25°C by the syringe pump addition of tert-alkyl hydroperoxides (10 and 1 equiv based on catalyst) to deoxygenated acetonitrile containing cycloalkanes (0.64 M) and 0.61 mM of the catalyst, [Fem(III)2O(TPA)2(H2O)2]4+, is demonstrated to be a reaction which involves freely diffusing cycloalkyl radicals, i.e., free alkyl radicals.",

author = "MacFaul, {Philip A.} and Ingold, {K. U.} and Wayner, {D. D M} and Lawrence Que",

year = "1997",

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pages = "10594--10598",

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T1 - A putative monooxygenase mimic which functions via well-disguised free radical chemistry

AU - MacFaul, Philip A.

AU - Ingold, K. U.

AU - Wayner, D. D M

AU - Que, Lawrence

PY - 1997

Y1 - 1997

N2 - The hydroxylation of cycloalkanes at 25°C by the syringe pump addition of tert-alkyl hydroperoxides (10 and 1 equiv based on catalyst) to deoxygenated acetonitrile containing cycloalkanes (0.64 M) and 0.61 mM of the catalyst, [Fem(III)2O(TPA)2(H2O)2]4+, is demonstrated to be a reaction which involves freely diffusing cycloalkyl radicals, i.e., free alkyl radicals.

AB - The hydroxylation of cycloalkanes at 25°C by the syringe pump addition of tert-alkyl hydroperoxides (10 and 1 equiv based on catalyst) to deoxygenated acetonitrile containing cycloalkanes (0.64 M) and 0.61 mM of the catalyst, [Fem(III)2O(TPA)2(H2O)2]4+, is demonstrated to be a reaction which involves freely diffusing cycloalkyl radicals, i.e., free alkyl radicals.

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JF - Journal of the American Chemical Society

IS - 44

ER -

A putative monooxygenase mimic which functions via well-disguised free radical chemistry

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