A quantitative structure-activity relationship study of N-alkylnorketobemidones and triazinones using structural information content

S. K. Ray, S. C. Basak, C. Raychaudhury, A. B. Roy, J. J. Ghosh

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

A newly formulated information-theoretic topological index, structural information content (SIC), was applied to quantitative structure-activity relationship (QSAR) studies with N-alkylnorketobemidones and triazinones. Results show that SIC encodes sufficient molecular structural information to correlate significantly with the physical as well as biological properties of both the groups of congeners.

Original languageEnglish (US)
Pages (from-to)322-325
Number of pages4
JournalArzneimittel-Forschung/Drug Research
Volume32
Issue number4
StatePublished - Jun 11 1982

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