TY - JOUR
T1 - Active interfacial shear microrheology of aging protein films
AU - Dhar, Prajnaparamita
AU - Cao, Yanyan
AU - Fischer, Thomas M.
AU - Zasadzinski, J. A.
PY - 2010/1/4
Y1 - 2010/1/4
N2 - The magnetically driven rotation of 300 nm diameter rods shows the surface viscosity of albumin at an air-water interface increases from 10-9 to 10-5Ns/m over 2 h while the surface pressure saturates in minutes. The increase in surface viscosity is not accompanied by a corresponding increase in elasticity, suggesting that the protein film anneals with time, resulting in a more densely packed film leading to increased resistance to shear. The nanometer dimensions of the rods provide the same sensitivity as passive microrheology with an improved ability to measure more viscous films.
AB - The magnetically driven rotation of 300 nm diameter rods shows the surface viscosity of albumin at an air-water interface increases from 10-9 to 10-5Ns/m over 2 h while the surface pressure saturates in minutes. The increase in surface viscosity is not accompanied by a corresponding increase in elasticity, suggesting that the protein film anneals with time, resulting in a more densely packed film leading to increased resistance to shear. The nanometer dimensions of the rods provide the same sensitivity as passive microrheology with an improved ability to measure more viscous films.
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U2 - 10.1103/PhysRevLett.104.016001
DO - 10.1103/PhysRevLett.104.016001
M3 - Article
C2 - 20366371
AN - SCOPUS:73649086231
SN - 0031-9007
VL - 104
JO - Physical review letters
JF - Physical review letters
IS - 1
M1 - 016001
ER -