TY - JOUR
T1 - Acute polyosteal osteomyelitis in a patient with congenital ichthyosis and acute lymphoblastic leukemia
AU - Tolar, Jakub
AU - Kravitz, Gary
AU - Walker, Kevin
AU - Moertel, Christopher L
PY - 2001
Y1 - 2001
N2 - Osteomyelitis can develop after bacteremia in children and is a rare complication of chemotherapy for acute lymphoblastic leukemia. A child with congenital ichthyosis, acute lymphoblastic leukemia and multifocal hematogenous osteomyelitis is described herein. A breached skin barrier secondary to ichthyosis during induction chemotherapy, coupled with impaired immunity, likely provided the opportunity for bacterial seeding, leading to an extensive multifocal osteomyelitis.
AB - Osteomyelitis can develop after bacteremia in children and is a rare complication of chemotherapy for acute lymphoblastic leukemia. A child with congenital ichthyosis, acute lymphoblastic leukemia and multifocal hematogenous osteomyelitis is described herein. A breached skin barrier secondary to ichthyosis during induction chemotherapy, coupled with impaired immunity, likely provided the opportunity for bacterial seeding, leading to an extensive multifocal osteomyelitis.
KW - Child
KW - Ichthyosiform
KW - Intraosseous tobramycin beads
KW - Nonbullous congenital ichthyosiform erythroderma
KW - Orthopedic
KW - Staphylococcus aureus
UR - http://www.scopus.com/inward/record.url?scp=0034892823&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034892823&partnerID=8YFLogxK
U2 - 10.1097/00006454-200108000-00022
DO - 10.1097/00006454-200108000-00022
M3 - Article
C2 - 11734751
AN - SCOPUS:0034892823
SN - 0891-3668
VL - 20
SP - 813
EP - 814
JO - Pediatric Infectious Disease Journal
JF - Pediatric Infectious Disease Journal
IS - 8
ER -
