Adaptation and divergence during experimental evolution of multicellular Saccharomyces cerevisiae

Maria Rebolleda-Gomez, William Ratcliff, Michael Travisano

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations

Abstract

The evolution of multicellularity was one of the key innovations in the history of life on Earth. Virtually all morphological and ecological diversity in macro-organisms builds upon the evolutionary potential associated with multicellularity. We examined the potential for ecological diversity to rapidly arise following transitions to multicellularity. Replicate microcosms containing the yeast Saccharomyces cerevisiae were maintained under serial transfer. Prior to transfer to fresh media each day, S. cerevisiae underwent settling selection via mild centrifugation. Those individuals reaching the bottom of the centrifuge tube were transferred to fresh media. After sixty days, all microcosms contained multicellular individuals that develop via mother-daughter adhesion. In nine of the ten microcosms, at least two distinctive morphological genotypes were evident at sixty days, and in eight of them, the variants were multicellular. We observed substantial morphological variation across replicates, with relatively little parallelism in the size of multicellular individuals or in the size variation within microcosms. These results suggest surprising amounts of contingency in the evolution of ecological diversity, and that "replaying life's tape" would lead to divergent outcomes.

Original languageEnglish (US)
Title of host publicationArtificial Life 13
Subtitle of host publicationProceedings of the 13th International Conference on the Simulation and Synthesis of Living Systems, ALIFE 2012
Pages99-104
Number of pages6
StatePublished - Dec 1 2012
Event13th International Conference on the Simulation and Synthesis of Living Systems: Artificial Life 13, ALIFE 2012 - East Lansing, MI, United States
Duration: Jul 19 2012Jul 22 2012

Publication series

NameArtificial Life 13: Proceedings of the 13th International Conference on the Simulation and Synthesis of Living Systems, ALIFE 2012

Other

Other13th International Conference on the Simulation and Synthesis of Living Systems: Artificial Life 13, ALIFE 2012
CountryUnited States
CityEast Lansing, MI
Period7/19/127/22/12

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