Adrenal Corticosteroids Cause Gastrin Cell Hyperplasia

John P. Delaney, Hector M. Michel, Margaret E. Bonsack, M. Michael Eisenberg, Daniel H. Dunn

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Chronic exogenous high dose adrenal cortical steroid administration to dogs resulted in a 137% increase in G-cell mass with an associated enhancement of peak serum gastrin levels. Adrenalectomy caused a halving of G-cell numbers without significant changes in serum gastrin levels. Adrenal cortical steroids appear to have an important trophic role for the G-cell.

Original languageEnglish (US)
Pages (from-to)913-916
Number of pages4
JournalGastroenterology
Volume76
Issue number5
DOIs
StatePublished - 1979

Fingerprint Dive into the research topics of 'Adrenal Corticosteroids Cause Gastrin Cell Hyperplasia'. Together they form a unique fingerprint.

Cite this