Aging reduces somatosensory responsiveness of caudate neurons in the awake cat

M. S. Levine; J. S. Schneider; R. L. Lloyd; C. D. Hull; N. A. Buchwald

doi:10.1016/0006-8993(87)90312-X

Aging reduces somatosensory responsiveness of caudate neurons in the awake cat

M. S. Levine, J. S. Schneider, R. L. Lloyd, C. D. Hull, N. A. Buchwald

Psychology (Duluth)

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Neuronal activity was recorded in 7 awake cats (3 animals 11-15 years and 4 animals 1-3 years of age) to determine if the ability of caudate neurons to process facial somatosensory information was impaired in aged animals. Proportionately fewer neurons responded to somatosensory stimuli and facial receptive fields were larger in the aged cats. In addition, proportionately fewer caudate neurons responded to cortical activation, there were fewer excitatory responses and spontaneous firing decreased in aged cats. These results provide additional evidence that excitability of caudate neurons is reduced in aged cats.

Original language	English (US)
Pages (from-to)	389-394
Number of pages	6
Journal	Brain Research
Volume	405
Issue number	2
DOIs	https://doi.org/10.1016/0006-8993(87)90312-X
State	Published - Mar 10 1987

Bibliographical note

Funding Information:
Supported by USPHS Grants AG 01558 and HD 05958.

Keywords

Aged cat
Caudate nucleus
Chronic recording
Neurophysiology
Reduced excitability

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title = "Aging reduces somatosensory responsiveness of caudate neurons in the awake cat",

abstract = "Neuronal activity was recorded in 7 awake cats (3 animals 11-15 years and 4 animals 1-3 years of age) to determine if the ability of caudate neurons to process facial somatosensory information was impaired in aged animals. Proportionately fewer neurons responded to somatosensory stimuli and facial receptive fields were larger in the aged cats. In addition, proportionately fewer caudate neurons responded to cortical activation, there were fewer excitatory responses and spontaneous firing decreased in aged cats. These results provide additional evidence that excitability of caudate neurons is reduced in aged cats.",

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AU - Levine, M. S.

AU - Schneider, J. S.

AU - Lloyd, R. L.

AU - Hull, C. D.

AU - Buchwald, N. A.

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AB - Neuronal activity was recorded in 7 awake cats (3 animals 11-15 years and 4 animals 1-3 years of age) to determine if the ability of caudate neurons to process facial somatosensory information was impaired in aged animals. Proportionately fewer neurons responded to somatosensory stimuli and facial receptive fields were larger in the aged cats. In addition, proportionately fewer caudate neurons responded to cortical activation, there were fewer excitatory responses and spontaneous firing decreased in aged cats. These results provide additional evidence that excitability of caudate neurons is reduced in aged cats.

KW - Aged cat

KW - Caudate nucleus

KW - Chronic recording

KW - Neurophysiology

KW - Reduced excitability

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Aging reduces somatosensory responsiveness of caudate neurons in the awake cat

Abstract

Bibliographical note

Keywords

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