TY - JOUR
T1 - Air pollution and cardiovascular disease
T2 - A statement for healthcare professionals from the expert panel on population and prevention science of the American Heart Association
AU - Brook, Robert D.
AU - Franklin, Barry
AU - Cascio, Wayne
AU - Hong, Yuling
AU - Howard, George
AU - Lipsett, Michael
AU - Luepker, Russell
AU - Mittleman, Murray
AU - Samet, Jonathan
AU - Smith, Sidney C.
AU - Tager, Ira
PY - 2004/6/1
Y1 - 2004/6/1
N2 - Air pollution is a heterogeneous, complex mixture of gases, liquids, and particulate matter. Epidemiological studies have demonstrated a consistent increased risk for cardiovascular events in relation to both short- and long-term exposure to present-day concentrations of ambient particulate matter. Several plausible mechanistic pathways have been described, including enhanced coagulation/thrombosis, a propensity for arrhythmias, acute arterial vasoconstriction, systemic inflammatory responses, and the chronic promotion of atherosclerosis. The purpose of this statement is to provide healthcare professionals and regulatory agencies with a comprehensive review of the literature on air pollution and cardiovascular disease. In addition, the implications of these findings in relation to public health and regulatory policies are addressed. Practical recommendations for healthcare providers and their patients are outlined. In the final section, suggestions for future research are made to address a number of remaining scientific questions.
AB - Air pollution is a heterogeneous, complex mixture of gases, liquids, and particulate matter. Epidemiological studies have demonstrated a consistent increased risk for cardiovascular events in relation to both short- and long-term exposure to present-day concentrations of ambient particulate matter. Several plausible mechanistic pathways have been described, including enhanced coagulation/thrombosis, a propensity for arrhythmias, acute arterial vasoconstriction, systemic inflammatory responses, and the chronic promotion of atherosclerosis. The purpose of this statement is to provide healthcare professionals and regulatory agencies with a comprehensive review of the literature on air pollution and cardiovascular disease. In addition, the implications of these findings in relation to public health and regulatory policies are addressed. Practical recommendations for healthcare providers and their patients are outlined. In the final section, suggestions for future research are made to address a number of remaining scientific questions.
KW - AHA Scientific Statements
KW - Air pollution
KW - Cardiovascular diseases
KW - Respiration
UR - http://www.scopus.com/inward/record.url?scp=2642540057&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=2642540057&partnerID=8YFLogxK
U2 - 10.1161/01.CIR.0000128587.30041.C8
DO - 10.1161/01.CIR.0000128587.30041.C8
M3 - Review article
C2 - 15173049
AN - SCOPUS:2642540057
SN - 0009-7322
VL - 109
SP - 2655
EP - 2671
JO - Circulation
JF - Circulation
IS - 21
ER -