Amino acid sequence of a vitamin K dependent Ca2+ binding peptide from bovine prothrombin

J. B. Howard, M. D. Fausch, G. L. Nelsestuen

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Abstract

The amino acid sequence of a 31 residue peptide from bovine prothrombin has been determined. This peptide has been shown to contain the vitamin K dependent modification required for Ca2+ binding and the modified amino acid, γ carboxyglutamic acid. The peptide was shown to correspond to residues 12 to 42 of prothrombin.

Original languageEnglish (US)
Pages (from-to)6178-6180
Number of pages3
JournalJournal of Biological Chemistry
Volume250
Issue number15
StatePublished - 1975

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