At discharge, a significantly larger percentage of unipolar patients treated with electroconvulsive therapy (ECT) respond with marked improvement as compared with those receiving antidepressants or other treatment. No treatment appears to be more efficacious in the bipolar group. In studying the covariables related to the length of time between hospitalizations, we found that the type of treatment is not important for the unipolar patient, whereas a combination of ECT and antidepressants lengthens the time to rehospitalization of the bipolar patient. Previous hospitalization is an important predictor variable for all patients.
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that significantly more ECT patients recovered completely than the AD groups. Two prospective studies of interest are those made by the Medical Research Council (1965) and Greenblatt et al. (1964). These investigators allocated patients at random to various ECT, AD treatment and placebo groups. After an 8-weekand4-weektreatmentperiod, respectively, Greenblatt et al. and the Medical Research Council both reported that ECT was significantly superior to various antidepressant drugs in terms of response rates of marked improvement.