Abstract
An efficient methodology for the preparation of α-hydroxyamides via boric acid-mediated addition of isonitriles onto aldehydes has been developed. The reaction of isonitriles with α-boronobenzaldehyde takes place under intramolecular catalysis conditions to provide functionalized benzoxaboroles.
Original language | English (US) |
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Pages (from-to) | 779-782 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 51 |
Issue number | 5 |
DOIs | |
State | Published - Feb 3 2010 |
Keywords
- Benzoxaboroles
- Boric acid
- Isonitriles
- Multicomponent reactions