Abstract
Efficient reduction of mono- and disubstituted norbornyl α-diketones with zinc in [bmimBF4]:[H2O] to afford the corresponding acyloins in excellent yields and diastereoselectivities is described. In case of the monosubstituted norbornyl α-diketones, very high regioselectivities ranging from 90:10 to 100:0, in favor of diastereomer possessing endohydroxyl diagonal to endo-substituent were observed.
Original language | English (US) |
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Pages (from-to) | 222-228 |
Number of pages | 7 |
Journal | Arkivoc |
Volume | 2009 |
Issue number | 7 |
DOIs | |
State | Published - Apr 12 2009 |
Keywords
- Acyloins
- Ionic liquid
- Regioisomers
- Zinc
- α-Diketones