An etiologic basis for congestive heart failure on the molecular level

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

It is here proposed that disordered redox balance leads to congestive heart failure in a variety of diverse clinical situations. These conditions include those associated with an excess of reducing agents, such as catecholamines and thyroid hormone, or impaired oxidant defenses, such as in selenium deficiency. The clinical situations include hypertension, hyperthyroidism, progressive congestive heart failure, amphetamine overdose and hemochromatosis. The molecular damage to the cardiac muscle is postulated to be mediated via reaction oxygen radicals.

Original languageEnglish (US)
Pages (from-to)109-113
Number of pages5
JournalMedical Hypotheses
Volume13
Issue number1
DOIs
StatePublished - Jan 1984

Fingerprint

Dive into the research topics of 'An etiologic basis for congestive heart failure on the molecular level'. Together they form a unique fingerprint.

Cite this