An interactive graphical user interface for comprehensive analysis of human and swine cardiac monophasic action potential

Maneesh Shrivastav; Paul A. Iaizzo

doi:10.1016/j.compbiomed.2009.09.005

An interactive graphical user interface for comprehensive analysis of human and swine cardiac monophasic action potential

Maneesh Shrivastav, Paul A. Iaizzo

Surgery

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4 Scopus citations

Abstract

This research describes a novel monophasic action potential (MAP) annotation algorithm coupled with an interactive graphical user interface (GUI). This algorithm incorporates a number of features to reduce error. Additionally, the GUI has several convenient features to view and manipulate the annotation visually. We analyzed data from swine and human hearts in normal sinus rhythm, during myocardial ischemia, and while eliciting high rates. Validation results indicate correlation >90% between human and computer measurements. This analysis system has several clinical applications in electrophysiological interventions, pharmacodynamic therapies, ischemia detection, and/or in assessment of the time course of electrical activation.

Original language	English (US)
Pages (from-to)	1105-1116
Number of pages	12
Journal	Computers in Biology and Medicine
Volume	39
Issue number	12
DOIs	https://doi.org/10.1016/j.compbiomed.2009.09.005
State	Published - Dec 2009

Keywords

Cardiac arrhythmia
Computer analysis
Graphical user interface
MAP
Monophasic action potential
Signal processing

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AB - This research describes a novel monophasic action potential (MAP) annotation algorithm coupled with an interactive graphical user interface (GUI). This algorithm incorporates a number of features to reduce error. Additionally, the GUI has several convenient features to view and manipulate the annotation visually. We analyzed data from swine and human hearts in normal sinus rhythm, during myocardial ischemia, and while eliciting high rates. Validation results indicate correlation >90% between human and computer measurements. This analysis system has several clinical applications in electrophysiological interventions, pharmacodynamic therapies, ischemia detection, and/or in assessment of the time course of electrical activation.

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KW - Signal processing

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An interactive graphical user interface for comprehensive analysis of human and swine cardiac monophasic action potential

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