An organo-catalytic approach to the enantioselective synthesis of (R)-selegiline

Siva Kumar Talluri; Arumugam Sudalai

doi:10.1016/j.tet.2007.07.012

An organo-catalytic approach to the enantioselective synthesis of (R)-selegiline

Siva Kumar Talluri, Arumugam Sudalai

Chemistry (Twin Cities)

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

An efficient enantioselective synthesis of (R)-selegiline has been achieved by two routes, via proline-catalyzed α-aminooxylation as well as α-amination of phenylpropanaldehyde as the key step.

Original language	English (US)
Pages (from-to)	9758-9763
Number of pages	6
Journal	Tetrahedron
Volume	63
Issue number	39
DOIs	https://doi.org/10.1016/j.tet.2007.07.012
State	Published - Sep 24 2007

Bibliographical note

Funding Information:
S.K.T. thanks CSIR, New Delhi, for financial support. The authors thank Dr. B. D. Kulkarni, Head, CE-PD Division, for his constant encouragement and support.

Keywords

Asymmetric reactions
Organocatalysis
Proline
α-Amination
α-Aminooxylation

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abstract = "An efficient enantioselective synthesis of (R)-selegiline has been achieved by two routes, via proline-catalyzed α-aminooxylation as well as α-amination of phenylpropanaldehyde as the key step.",

keywords = "Asymmetric reactions, Organocatalysis, Proline, α-Amination, α-Aminooxylation",

author = "Talluri, {Siva Kumar} and Arumugam Sudalai",

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AU - Sudalai, Arumugam

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KW - Organocatalysis

KW - Proline

KW - α-Amination

KW - α-Aminooxylation

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An organo-catalytic approach to the enantioselective synthesis of (R)-selegiline

Abstract

Bibliographical note

Keywords

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