ANKH Polymorphisms and Clicking of the Temporomandibular Joint in Dental Residents

Boyen Huang; Katsu Takahashi; Tomoko Goto; Honoka Kiso; Manabu Sugai; Akira Shimizu; Shinji Kosugi; Kazuhisa Bessho

doi:10.1007/s12663-014-0622-z

ANKH Polymorphisms and Clicking of the Temporomandibular Joint in Dental Residents

Boyen Huang, Katsu Takahashi, Tomoko Goto, Honoka Kiso, Manabu Sugai, Akira Shimizu, Shinji Kosugi, Kazuhisa Bessho

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Aim: This study aimed to carry out a case-control research study to assess occurrence of clicking of the temporomandibular joint (TMJ) in order to establish the relationship between TMJ clicking and the genotype of “ANKH inorganic pyrophosphate transport regulator” (ANKH) polymorphisms. Materials and Method: A sample of 41 first-year dental residents was selected. Each was examined using standard clinical procedures and genotyping techniques. Results: The participation rate was 91.8 %. The prevalence of TMJ clicking was 51.2 % (95 % CI: 35.7–66.7 %). Occurrence of TMJ clicking was not related to age, gender and genotypes of ANKH-OR as well as ANKH-TR polymorphisms (p ≥ 0.165). Conclusion: A similar distribution of ANKH genotypes in TMJ clicking and asymptomatic individuals has been demonstrated by this study. A high percentage of TMJ clicking has been confirmed. Future investigations are indicated.

Original language	English (US)
Pages (from-to)	247-251
Number of pages	5
Journal	Journal of Maxillofacial and Oral Surgery
Volume	14
Issue number	2
DOIs	https://doi.org/10.1007/s12663-014-0622-z
State	Published - Jun 1 2015
Externally published	Yes

Bibliographical note

Funding Information:
This study was supported by a Grant-in-Aid for Scientific Research (B) from Japanese Society for the Promotion of Science. The authors would like to show appreciation to those staff and students who helped in this project.

Funding Information:
This study was supported by a Grant-in-Aid for Scientific Research (B) from Japanese Society for the Promotion of Science. The authors would like to show appreciation to those staff and students who helped in this project.

Publisher Copyright:
© 2014, Association of Oral and Maxillofacial Surgeons of India.

Keywords

ANKH
Clicking
Oral surgeon
Polymorphism
Temporomandibular disorders

Access

10.1007/s12663-014-0622-z

OpenUrl availability

Full text

Cite this

@article{fa0e670dbdf545fcbd223bce56d38ede,

title = "ANKH Polymorphisms and Clicking of the Temporomandibular Joint in Dental Residents",

abstract = "Aim: This study aimed to carry out a case-control research study to assess occurrence of clicking of the temporomandibular joint (TMJ) in order to establish the relationship between TMJ clicking and the genotype of “ANKH inorganic pyrophosphate transport regulator” (ANKH) polymorphisms. Materials and Method: A sample of 41 first-year dental residents was selected. Each was examined using standard clinical procedures and genotyping techniques. Results: The participation rate was 91.8 %. The prevalence of TMJ clicking was 51.2 % (95 % CI: 35.7–66.7 %). Occurrence of TMJ clicking was not related to age, gender and genotypes of ANKH-OR as well as ANKH-TR polymorphisms (p ≥ 0.165). Conclusion: A similar distribution of ANKH genotypes in TMJ clicking and asymptomatic individuals has been demonstrated by this study. A high percentage of TMJ clicking has been confirmed. Future investigations are indicated.",

keywords = "ANKH, Clicking, Oral surgeon, Polymorphism, Temporomandibular disorders",

author = "Boyen Huang and Katsu Takahashi and Tomoko Goto and Honoka Kiso and Manabu Sugai and Akira Shimizu and Shinji Kosugi and Kazuhisa Bessho",

note = "Funding Information: This study was supported by a Grant-in-Aid for Scientific Research (B) from Japanese Society for the Promotion of Science. The authors would like to show appreciation to those staff and students who helped in this project. Funding Information: This study was supported by a Grant-in-Aid for Scientific Research (B) from Japanese Society for the Promotion of Science. The authors would like to show appreciation to those staff and students who helped in this project. Publisher Copyright: {\textcopyright} 2014, Association of Oral and Maxillofacial Surgeons of India.",

year = "2015",

month = jun,

day = "1",

doi = "10.1007/s12663-014-0622-z",

language = "English (US)",

volume = "14",

pages = "247--251",

journal = "Journal of Maxillofacial and Oral Surgery",

issn = "0972-8279",

publisher = "Springer India",

number = "2",

}

TY - JOUR

T1 - ANKH Polymorphisms and Clicking of the Temporomandibular Joint in Dental Residents

AU - Huang, Boyen

AU - Takahashi, Katsu

AU - Goto, Tomoko

AU - Kiso, Honoka

AU - Sugai, Manabu

AU - Shimizu, Akira

AU - Kosugi, Shinji

AU - Bessho, Kazuhisa

N1 - Funding Information: This study was supported by a Grant-in-Aid for Scientific Research (B) from Japanese Society for the Promotion of Science. The authors would like to show appreciation to those staff and students who helped in this project. Funding Information: This study was supported by a Grant-in-Aid for Scientific Research (B) from Japanese Society for the Promotion of Science. The authors would like to show appreciation to those staff and students who helped in this project. Publisher Copyright: © 2014, Association of Oral and Maxillofacial Surgeons of India.

PY - 2015/6/1

Y1 - 2015/6/1

N2 - Aim: This study aimed to carry out a case-control research study to assess occurrence of clicking of the temporomandibular joint (TMJ) in order to establish the relationship between TMJ clicking and the genotype of “ANKH inorganic pyrophosphate transport regulator” (ANKH) polymorphisms. Materials and Method: A sample of 41 first-year dental residents was selected. Each was examined using standard clinical procedures and genotyping techniques. Results: The participation rate was 91.8 %. The prevalence of TMJ clicking was 51.2 % (95 % CI: 35.7–66.7 %). Occurrence of TMJ clicking was not related to age, gender and genotypes of ANKH-OR as well as ANKH-TR polymorphisms (p ≥ 0.165). Conclusion: A similar distribution of ANKH genotypes in TMJ clicking and asymptomatic individuals has been demonstrated by this study. A high percentage of TMJ clicking has been confirmed. Future investigations are indicated.

AB - Aim: This study aimed to carry out a case-control research study to assess occurrence of clicking of the temporomandibular joint (TMJ) in order to establish the relationship between TMJ clicking and the genotype of “ANKH inorganic pyrophosphate transport regulator” (ANKH) polymorphisms. Materials and Method: A sample of 41 first-year dental residents was selected. Each was examined using standard clinical procedures and genotyping techniques. Results: The participation rate was 91.8 %. The prevalence of TMJ clicking was 51.2 % (95 % CI: 35.7–66.7 %). Occurrence of TMJ clicking was not related to age, gender and genotypes of ANKH-OR as well as ANKH-TR polymorphisms (p ≥ 0.165). Conclusion: A similar distribution of ANKH genotypes in TMJ clicking and asymptomatic individuals has been demonstrated by this study. A high percentage of TMJ clicking has been confirmed. Future investigations are indicated.

KW - ANKH

KW - Clicking

KW - Oral surgeon

KW - Polymorphism

KW - Temporomandibular disorders

UR - http://www.scopus.com/inward/record.url?scp=85042037089&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85042037089&partnerID=8YFLogxK

U2 - 10.1007/s12663-014-0622-z

DO - 10.1007/s12663-014-0622-z

M3 - Article

AN - SCOPUS:85042037089

SN - 0972-8279

VL - 14

SP - 247

EP - 251

JO - Journal of Maxillofacial and Oral Surgery

JF - Journal of Maxillofacial and Oral Surgery

IS - 2

ER -

ANKH Polymorphisms and Clicking of the Temporomandibular Joint in Dental Residents

Abstract

Bibliographical note

Keywords

Access

OpenUrl availability

Other files and links

Fingerprint

Cite this