Anti-endotoxin agents. 2. Pilot high-throughput screening for novel lipopolysaccharide-recognizing motifs in small molecules

Engineering & Materials Science

• Molecules 74%
• Screening 71%
• Lead compounds 64%
• Bioassay 57%
• Titration 54%
• Throughput 53%
• Lipids 51%
• Calorimetry 50%
• Toxicity 45%
• Assays 44%
• Fluorescence 43%
• Phosphates 43%
• Bacteria 42%
• Enthalpy 39%
• Binders 35%
• Membranes 32%

Chemical Compounds

• Endotoxin 100%
• High Throughput Screening 82%
• Lipopolysaccharide 63%
• Molecule 26%
• Lipid A 25%
• Isothermal Titration Calorimetry 21%
• Bioassay 18%
• Fluorescent Probe 17%
• Binding Agent 16%
• Displacement 15%
• Enthalpy 15%
• Phosphate 12%
• Modification 10%

Medicine & Life Sciences

• Endotoxins 76%
• Lipopolysaccharides 65%
• High-Throughput Screening Assays 27%
• Calorimetry 26%
• Lipid A 25%
• Fluorescent Dyes 20%
• Biological Assay 20%
• Septic Shock 19%
• Gram-Negative Bacteria 19%
• Critical Illness 17%
• Phosphates 16%
• Fluorescence 15%
• Sepsis 15%
• Databases 11%
• Membranes 11%
• Mortality 9%
• In Vitro Techniques 8%
• Therapeutics 6%