Antibody Response in the Rat II. Microclasmatosis, a Possible Mode of Antibody Release

Seong S. Han, Ihn H. Han, Arthur G. Johnson

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Electron microscopic observations were made of cells in spleens taken from Sprague-Dawley rats during the primary antibody response to bovine gamma globulin. Many of the resulting plasma cells were found to produce a series of vesicles by membrane invaginations which surrounded small pieces of the rough-surfaced endoplasmic reticulum (RER). By coalescence of these vesicles, chunks of cytoplasm containing the RER appeared to be liberated from the plasmacytic cells. The process, microclasmatosis, was postulated to represent one physiological way of release and transport of formed antibody globulins.

Original languageEnglish (US)
Pages (from-to)782-785
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume121
Issue number3
DOIs
StatePublished - Mar 1966

Fingerprint Dive into the research topics of 'Antibody Response in the Rat II. Microclasmatosis, a Possible Mode of Antibody Release'. Together they form a unique fingerprint.

Cite this