Antistreptokinase antibodies before and after streptokinase therapy in patients with acute myocardial infarction from areas endemic for streptococcal infection and influence on reperfusion rates

Garg Shaila; Y. S. Chandrashekhar; Nanda Kumar; Nirmal K. Ganguly; Inder S. Anand

doi:10.1016/0002-9149(94)90099-X

Antistreptokinase antibodies before and after streptokinase therapy in patients with acute myocardial infarction from areas endemic for streptococcal infection and influence on reperfusion rates

Garg Shaila, Y. S. Chandrashekhar, Nanda Kumar, Nirmal K. Ganguly, Inder S. Anand

Medicine - Veteran's Administration Medical Center

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Abstract

We conclude that patients with myocardial infarction from areas endemic for streptococcal infection have high levels of preexisting ASK antibodies. However, these antibodies do not appear to interfere with the efficacy of reperfusion with streptokinase. Similarly, high basal ASK antibody titers do not increase the risk of allergic reactions to streptokinase.

Original language	English (US)
Pages (from-to)	187-189
Number of pages	3
Journal	The American Journal of Cardiology
Volume	74
Issue number	2
DOIs	https://doi.org/10.1016/0002-9149(94)90099-X
State	Published - Jul 15 1994

Bibliographical note

Funding Information:
From the Department of Forensic Medicine, University of Uppsala, Uppsala, Sweden, and the Department of Medicine, University of Florida College of Medicine, Gainesville, Florida. This study was supported by grants from the Swedish Medical Research Council, Stockholm, Sweden, and the American Heart Association, Florida Affiliate, St. Petersburg, Florida. Manuscript received September 10, 1993; revised manuscript received and accepted January 3, 1994.

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Shaila, G., Chandrashekhar, Y. S., Kumar, N., Ganguly, N. K., & Anand, I. S. (1994). Antistreptokinase antibodies before and after streptokinase therapy in patients with acute myocardial infarction from areas endemic for streptococcal infection and influence on reperfusion rates. The American Journal of Cardiology, 74(2), 187-189. https://doi.org/10.1016/0002-9149(94)90099-X

Antistreptokinase antibodies before and after streptokinase therapy in patients with acute myocardial infarction from areas endemic for streptococcal infection and influence on reperfusion rates. / Shaila, Garg; Chandrashekhar, Y. S.; Kumar, Nanda et al.
In: The American Journal of Cardiology, Vol. 74, No. 2, 15.07.1994, p. 187-189.

Research output: Contribution to journal › Article › peer-review

Shaila, G, Chandrashekhar, YS, Kumar, N, Ganguly, NK & Anand, IS 1994, 'Antistreptokinase antibodies before and after streptokinase therapy in patients with acute myocardial infarction from areas endemic for streptococcal infection and influence on reperfusion rates', The American Journal of Cardiology, vol. 74, no. 2, pp. 187-189. https://doi.org/10.1016/0002-9149(94)90099-X

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Antistreptokinase antibodies before and after streptokinase therapy in patients with acute myocardial infarction from areas endemic for streptococcal infection and influence on reperfusion rates

Abstract

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